Assuntos
Ética Clínica , Ética Profissional , Assistência ao Paciente , Recursos Humanos em Hospital , Aborto Induzido , Catolicismo , Consciência , Ética Clínica/educação , Pessoal de Saúde , Hospitais Religiosos , Humanos , Relações Interprofissionais , Relações Profissional-Paciente , Esterilização Reprodutiva , EstudantesRESUMO
Between 1971 and 1980, 385 patients with colposcopic biopsy-proved cervical intraepithelial neoplasia were treated by either the colposcopist or the referring physician by means of cryosurgery, electrocautery, or biopsy excision. All were observed for a minimum of 1 year, 220 between 1 and 2 years, 50 between 3 and 4 years, and 23 for 4 or more years. Therapy failed in 29 in the first year ("failures" proved by tissue examination). The failure rate among the 35 patients with carcinoma in situ was 20%, a rate significantly higher than that seen in 108 patients with severe dysplasia (7 or 6.5%) or in mild and moderate dysplasia (4.4% and 8.5%, respectively). There were 10 "recurrences" seen among those observed for more than 1 year after treatment. In eight instances the histologic severity of the recurrence was more severe than that of the original lesion. The comparative efficacy of cryosurgery and electrocautery and the success and failure rates for the colposcopists and other therapists who had not viewed the lesions prior to therapy are examined.
Assuntos
Procedimentos Cirúrgicos Ambulatórios , Carcinoma in Situ/cirurgia , Neoplasias do Colo do Útero/cirurgia , Adolescente , Adulto , Criança , Criocirurgia , Eletrocoagulação , Feminino , Seguimentos , Humanos , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/epidemiologia , Estudos Prospectivos , Estudos Retrospectivos , Displasia do Colo do Útero/cirurgiaAssuntos
Adenocarcinoma/etiologia , Congêneres do Estradiol/efeitos adversos , Neoplasias Uterinas/etiologia , Adenocarcinoma/epidemiologia , Idoso , Complicações do Diabetes , Feminino , Humanos , Hipertensão/complicações , Pessoa de Meia-Idade , Obesidade/complicações , Gravidez , Estudos Retrospectivos , Risco , Neoplasias Uterinas/epidemiologia , WisconsinRESUMO
Multiple drugs, a single drug, and irradiation were compared in patients with Stage III ovarian carcinoma. The results were categorized as "favorable" [pelvic mass less than 8 cm and/or upper abdominal tumor nodule(s) less than 2 cm] or "unfavorable" (more massive disease). A total of 62 patients are reviewed of whom 25 had irradiation and 37 had chemotherapy. It was found that patients with slight residual disease after celiotomy did equally well with either irradiation or chemotherapy, but survival was improved using a combination of both. Use of 5 drugs did not significantly improve survival beyond that obtained with a single drug.
