Spiral patterns in the packing of flexible structures.

Spiral patterns are found to be a generic feature in close-packed elastic structures. We describe model experiments of compaction of quasi-1D sheets into quasi-2D containers that allow simultaneous quantitative measurements of mechanical forces and observation of folded configurations. Our theoretical approach shows how the interplay between elasticity and geometry leads to a succession of bifurcations responsible for the emergence of such patterns. Both experimental forces and shapes are also reproduced without any adjustable parameters.

Immune function and renal transplantation in Fabry's disease.

A deficient leucocyte immunological function could cause the reported high rate of lethal infections following renal transplantation in patients affected by Fabry's disease. We have studied humoral immunity, peripheral lymphocyte subsets, mitogenic lymphocyte response in vitro and granulocyte function in three patients with Fabry's disease. The immunological state appears to be quite similar to that of the uraemic population in general, not showing any specific impairment.