[Variations in health-related quality of life in critical patients]. / Variaciones en la calidad de vida relacionada con la salud en los pacientes críticos.

OBJECTIVE: To determine the changes in the health-related quality of life (hRQOL) six months after discharge from the ICU and the conditions associated to them. DESIGN: A prospective cohort study. SETTING: 14 beds medical-surgical intensive care unit (ICU). PATIENTS: A total of 247 patients admitted to our ICU for more than 24 hours with a follow-up of 6 months were study. Those admitted with acute coronary syndrome or for monitoring purposes were excluded. INTERVENTION: A quality of life survey was conducted using the score developed by the PAEEC group (project of the epidemiological analysis of critical illness) to assess hRQOL before ICU admission and 6 months after discharge. RESULTS: The hRQOL deteriorated, going from a median value of 3 to 6 (p < 0.001). The multivariate analysis showed less deterioration of hRQOL in patients with chronic health conditions registered on the APAChE-II score (regression coefficient [RC] = -1.4; 95% CI, -2.5 to -0.2; p < 0.02) and in those with a hRQOL > or = 10 points (RC = -4,4; 95% CI, -5.9 to -2.8; p < 0.001). There was more deterioration in polytraumatized patients (RC = 1.9; 95% CI, 0.6-3.3; p = 0.01) or with renal failure (RC = 3.9; 95% CI, 1.9-5.9; p < 0.001) or in those with a stay duration longer than 10 days (RC = 1.9; 95% CI, 0.6-3.2; p < 0.001). CONCLUSIONS: Most patients experience deterioration of hRQOL. Patients with chronic diseases or with worst previous hRQOL who survive 6 months experience less deterioration of hRQOL than those who are polytraumatized or have renal failure or a longer ICU stay.

Variaciones en la calidad de vida relacionada con la salud en los pacientes críticos / Variations in health-related quality of life in critical patients

Objetivo. Analizar las variaciones de la calidad de vida relacionada con la salud (CVRS) a los 6 meses del alta de la unidad de medicina intensiva (UMI)y los factores que se asocian a estas variaciones. Diseño. Estudio prospectivo de cohortes. Ámbito. UMI médico-quirúrgica de 14 camas. Pacientes. Fueron 247 pacientes ingresados en UMI más de 24 h, con un seguimiento de 6 meses. Se excluyó a los pacientes con síndrome coronario agudo y los que ingresaban solamente para seguimiento. Intervención. Se realizó una encuesta de CVRS desarrollada por el grupo Proyecto para el Análisis Epidemiológico del Enfermo Crítico sobre su estado previo y a los 6 meses del alta de la UMI. Resultados. La CVRS se deteriora pasando de una mediana de 3 puntos a 6 (p < 0,001). El análisis multivariable muestra menor deterioro en la CVRS en pacientes con antecedentes registrados por el APAChE II (coeficiente de regresión [CR] = -1,4; intervalo de confianza [IC] del 95%, -2,5 a -0,2; p = 0,02) o una CVRS ≥ 10 puntos (CR = -4,4; IC del 95%, -5,9 a -2,8; p < 0,001) y mayor deterioro en pacientes politraumatizados (CR = 1,9; IC del 95%, 0,6-3,3; p < 0,01), con insuficiencia renal (CR = 3,9; IC del 95%, 1,9-5,9; p < 0,001) o estancia en UMI > 10 días (CR = 1,9; IC del 95%, 0,6-3,2; p = 0,004). Conclusiones. La mayoría de los pacientes muestran un deterioro de la CVRS. Los pacientes con enfermedades crónicas o con peor CVRS previa que han sobrevivido a los 6 meses muestran menor deterioro que los politraumatizados o con insuficiencia renal o estancias prolongadas en UMI (AU)

Objective. To determine the changes in the health-related quality of life (hRQOL) six months after discharge from the ICU and the conditions associated to them. Design. A prospective cohort study. Setting. 14 beds medical-surgical intensive care unit (ICU). Patients. A total of 247 patients admitted to our ICU for more than 24 hours with a follow-up of 6 months were study. Those admitted with acute coronary syndrome or for monitoring purposes were excluded. Intervention. A quality of life survey was conducted using the score developed by the PAEEC group (project of the epidemiological analysis of critical illness) to assess hRQOL before ICU admission and 6 months after discharge. Results. The hRQOL deteriorated, going from a median value of 3 to 6 (p < 0.001). The multivariate analysis showed less deterioration of hRQOL in patients with chronic health conditions registered on the APAChE-II score (regression coefficient [RC] = -1.4; 95% CI, -2.5 to -0.2; p < 0.02) and in those with a hRQOL ≥ 10 points (RC = -4,4; 95% CI, -5.9 to -2.8; p < 0.001). There was more deterioration in polytraumatized patients (RC = 1.9; 95% CI, 0.6-3.3; p = 0.01) or with renal failure (RC = 3.9; 95% CI, 1.9-5.9; p < 0.001) or in those with a stay duration longer than 10 days (RC = 1.9; 95% CI, 0.6-3.2; p < 0.001). Conclusions. Most patients experience deterioration of hRQOL. Patients with chronic diseases or with worst previous hRQOL who survive 6 months experience less deterioration of hRQOL than those who are polytraumatized or have renal failure or a longer ICU stay (AU)