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1.
East Mediterr Health J ; 26(11): 894-902, 2023 Nov 30.
Artigo em Inglês | MEDLINE | ID: mdl-38279885

RESUMO

Background: Cervical cancer places a significant burden on low- and middle-income countries (LMICs). The EuroMed Cancer Network (EuMedCN) brings together cancer experts and stakeholders from the Mediterranean countries to promote sustainable cancer screening and support implementation of the WHO Global Strategy to Accelerate the Elimination of Cervical Cancer as a Public Health Problem. Aim: To highlight the constructive role of EuMedCN in mitigating inequalities in access to cervical cancer prevention and screening across the Mediterranean LMICs. Methods: Through its workshops and meetings, EuMedCN members discussed new developments in cancer prevention and control, and how best to translate the WHO Global Strategy to Accelerate the Elimination of Cervical Cancer as a Public Health Problem into public health policies in the Mediterranean LMICs. This led to targeted actions in the selected countries. Results: Seven priority actions were implemented to improve cervical cancer screening in the Mediterranean LMICs. EuMedCN supported organized screening, new pilot technologies and enhancement of evaluation systems. Integrating cervical cancer screening into other disease programmes and fostering multidisciplinary networks were promoted as key to achieving targets of the WHO global strategy. Conclusion: International networks, such as EuMedCN, have the potential to bring together experts and stakeholders to share experiences and catalyse resource mobilization. They can support affordable and synergistic solutions for cervical cancer prevention.


Assuntos
Neoplasias do Colo do Útero , Feminino , Humanos , Neoplasias do Colo do Útero/diagnóstico , Neoplasias do Colo do Útero/prevenção & controle , Detecção Precoce de Câncer , Países em Desenvolvimento , Saúde Pública
3.
Br J Cancer ; 123(5): 714-721, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32546834

RESUMO

BACKGROUND: Improving the quality of information and communication is a priority in organised breast cancer screening and an ethical duty. Programmes must offer the information each woman is looking for, promoting informed decision-making. This study aimed to develop and evaluate a web-based dynamic decision aid (DA). METHODS: A pragmatic randomised trial carried out in six regional organised screening programmes recruited women at the first invitation receiving DA or a web-based standard brochure (SB). The primary outcome was informed choice measured on knowledge, attitudes, and intentions. Follow-up period: 7-10 days. Secondary outcomes included participation rate, satisfaction, decisional conflict, and acceptability of DA. RESULTS: Two thousand one hundred and nineteen women were randomised and 1001 completed the study. Respectively, 43.9% and 36.9% in the DA and SB reached the informed choice. The DA gave a 13-point higher proportion of women aware about overdiagnosis compared to SB (38.3% versus 25.2%, p < 0.0001). The percentage of women attending screening was the same: 84% versus 83%. Decisional conflict was significantly lower in the DA group (14.4%) than in the SB group (19.3%). CONCLUSION: DA increases informed choice. Complete information including the pros, cons, controversies, and overdiagnosis-overtreatment issues boost a woman's knowledge without reducing the rate of actual screening participation. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov number NCT03097653.


Assuntos
Neoplasias da Mama/diagnóstico , Técnicas de Apoio para a Decisão , Internet , Neoplasias da Mama/diagnóstico por imagem , Detecção Precoce de Câncer/métodos , Feminino , Humanos , Itália , Mamografia/métodos , Pessoa de Meia-Idade , Avaliação de Programas e Projetos de Saúde , Fatores Socioeconômicos
4.
Epidemiol Prev ; 44(5-6 Suppl 1): 115-123, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33415954

RESUMO

OBJECTIVES: to compare cervical cancer screening diagnostic indicators in women accessing screening through volunteer non-governmental organisations (NGOs) and in those who access via the National Health Service (NHS) programme. DESIGN: cohort study on archive data. SETTING AND PARTICIPANTS: the study cohort consists of 93,086 women aged 30-64 years who underwent an HPV test via NHS screening programme or through premises implemented within volunteers NGOs in Turin between 2015 and 2019. The screening history and Census data recorded into the Piedmont screening archive were used. MAIN OUTCOME MEASURES: positive baseline HPV test, positive triage cytology (low-grade lesions, ASC-US, L-SIL and high-grade lesions, H-SIL, ASC-H, AGC, Cancer), attendance at one-year HPV test repeat, referral and attendance to colposcopy at first and test repeat, and detection rate at first and test repeat, for cervical intraepithelial neoplasia grade >=2 (CIN2+) and >=3 (CIN3+), overall detection rates. RESULTS: women performing cervical screening through volunteer NGOs (WASVO) are disadvantaged in terms of diagnostic indicators compared to women accessing via the NHS. WASVO are 60% more likely to be positive at the first HPV-test (adjusted prevalence ratio 1.6; 95%CI 1.2-2.0); their likelihood of being referred to colposcopy is double (adj PR 2.1; 95%CI 1.3-3.4); attendance rate to one year HPV test repeat is lower (adj PR 0.2; 95%CI 0.1-0.5); detection rates at first HPV screening test both for CIN2+ (adj PR 2.1; 95%CI 0.9-4.6) and CIN3+ (adj PR 2.1; 95%CI 0.9-5.1) is higher, even if statistical significance is borderline for the latter results. CONCLUSIONS: those responsible for screening programmes should establish and maintain collaborative relationships with local volunteer NGOs and migrant organisations for promoting strategies to raise awareness on cancer prevention among subgroups that are not captured in the main screening programs.


Assuntos
Infecções por Papillomavirus , Displasia do Colo do Útero , Neoplasias do Colo do Útero , Adulto , Estudos de Coortes , Colposcopia , Detecção Precoce de Câncer , Feminino , Humanos , Itália/epidemiologia , Programas de Rastreamento , Pessoa de Meia-Idade , Papillomaviridae , Infecções por Papillomavirus/diagnóstico , Infecções por Papillomavirus/epidemiologia , Gravidez , Medicina Estatal , Neoplasias do Colo do Útero/diagnóstico , Neoplasias do Colo do Útero/epidemiologia , Esfregaço Vaginal , Voluntários , Displasia do Colo do Útero/diagnóstico , Displasia do Colo do Útero/epidemiologia
5.
Health Policy ; 121(10): 1072-1078, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28843514

RESUMO

Cervical cancer screening underutilisation is documented among immigrants from poor countries and it is associated to an augmented risk for severe lesions. In a cohort of 1,410,364 Italian women and 200,491 immigrants from poor countries differences in screening participation and results were investigated. Participation rate was lower for immigrants than for Italians: 43.98% versus 48.59% (chi(1): p<0.001). This gap increased with age (ptrend<0.0001). Some socio-demographic factors negatively influenced immigrants' participation. Illiteracy (OR=0.75) versus secondary school, being single (OR=0.71) versus attached, first screens (OR=0.67) versus subsequent ones. Although the interaction between educational and professional levels showed that graduated immigrant women conducting an intellectual job have a higher inclination towards screening than their Italian peers (OR=1.43 vs OR=1.04). The Standardised Detection Ratio (SDR) suggested a frequency of severe lesions nearly double among immigrants in first screens (SDR=1.94; 95% CI: 1.82-2.08) and even higher (SDR=2.53; 95% CI: 2.35-2.73) for Central/Eastern Europeans. Multi-component interventions involving both patients and providers offer the greatest potential to increase cervical cancer screening uptake within foreign-born populations. So immigrant-specific interventions are needed for some immigrant groups, like Central/Eastern Europeans who are at higher risk of cervical lesions and, together with Asians and Africans, showed a poor attitude towards cancer prevention.


Assuntos
Detecção Precoce de Câncer/estatística & dados numéricos , Emigrantes e Imigrantes/estatística & dados numéricos , Fatores Socioeconômicos , Neoplasias do Colo do Útero/diagnóstico , Adulto , Fatores Etários , Escolaridade , Feminino , Humanos , Itália/epidemiologia , Estado Civil , Pessoa de Meia-Idade , Teste de Papanicolaou , Neoplasias do Colo do Útero/epidemiologia
6.
Eur J Public Health ; 26(1): 83-9, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26072520

RESUMO

BACKGROUND: The EUROMED CANCER Network project aims to support non-EU Mediterranean countries in the development of cancer early detection and screening policies. METHODS: Through a structured questionnaire information from 15 countries (Albania, Algeria, Bosnia and Herzegovina (BiH), Croatia, Egypt, Jordan, UN Interim Administration Mission in Kosovo, Lebanon, Montenegro, Morocco, Palestinian National Authority, Serbia, Syria, Tunisia and Turkey) were collected on cancer epidemiology and control. RESULTS: Large differences between countries are evident. Breast cancer (BC) is the commonest cancer among women, though the incidence rate is much lower in non-EU than in EU Mediterranean countries. Conversely, cervical cancer (CC) is much more common in the former than in the latter countries. Colorectal cancer (CRC) is more frequent in Northern than in Eastern and Southern Mediterranean shores. Population-based cancer registries are available in few countries but most of them lack information on disease staging. Opportunistic screening for CC and BC is unevenly spread across and within countries; organised screening programmes are rare and do not meet international recommendations. BC and CC early detection is extensively considered a priority, while a few countries included CRC into their agenda. CONCLUSIONS: Collected data witnesses inadequacy of health information system and, in general, of the strategies for cancer control in the involved countries. A uniform approach for strengthening cancer control is not realistic neither feasible. Tailored preventive actions for cancer early detection have to be started concurrently with the development of a reliable health information system and, specifically, with cancer registration.


Assuntos
Detecção Precoce de Câncer/estatística & dados numéricos , Conhecimentos, Atitudes e Prática em Saúde , Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , África do Norte/epidemiologia , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/mortalidade , Neoplasias Colorretais/diagnóstico , Neoplasias Colorretais/mortalidade , Europa Oriental/epidemiologia , Feminino , Humanos , Oriente Médio/epidemiologia , Apoio Social , Neoplasias do Colo do Útero/diagnóstico , Neoplasias do Colo do Útero/mortalidade
7.
Epidemiol Prev ; 39(3 Suppl 1): 30-9, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26405774

RESUMO

Together with the National centre for screening monitoring (ONS), GISMa supports annual collection of data on national breast screening activities. Aggregated data on implementation and performance are gathered through a standardized form to calculate process and impact indicators. Analyzed data belong to 153 local programmes in the period 2006-2011 (2006-2012 for participation rate only). During the whole period, Italian crude participation rate exceeded GISMa's acceptable standard (50%), even though a higher participation in northern and central Italy compared to southern Italy and Islands was observed. Time trend analysis of diagnostic indicators confirmed in 2011 an adequate quality of breast screening performance, especially at subsequent screening. Recall rate at initial screening did not reach the acceptable standard (<7%) and rose slightly over the period. On the contrary, a good performance was achieved at subsequent screening. The same trend was followed by the overall detection rate and positive predictive value. They both showed a progressive reduction (from 6.2‰ in 2006 to 4.5‰ in 2011 for DR and from 8.0% in 2006 to 5.2% in 2011 for PPV, respectively) at initial screening and a good, stable trend at subsequent screening. Activity volume analysis shows that in programmes with greater activity (test/year ≥10,000) RR at both initial and subsequent screening has a better performance. This is also true for DR and PPV where programmes with high volumes of activity do better, especially when compared with those that interpret fewer than 5,000 mammograms per year. In spite of a few limits, these results are reassuring, and they reward the efforts made by screening professionals. It is therefore important to continue to monitor screening indicators and suggest, test, and evaluate new strategies for continuous improvement.


Assuntos
Neoplasias da Mama/diagnóstico , Neoplasias da Mama/epidemiologia , Carcinoma in Situ/diagnóstico , Carcinoma in Situ/epidemiologia , Mamografia/estatística & dados numéricos , Adulto , Detecção Precoce de Câncer/tendências , Feminino , Humanos , Itália/epidemiologia , Mamografia/tendências , Programas de Rastreamento/tendências , Padrões de Referência , Estudos Retrospectivos , Fatores de Tempo
8.
Epidemiol Prev ; 39(3 Suppl 1): 48-51, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26405776

RESUMO

Debate on efficacy, benefits, and risks of breast cancer screening continues to rage, and scientific controversy surrounding overdiagnosis, false positives/false negatives, raises questions about communication to women attending screening programmes. The study compares information provided by invitation letters and leaflets of Italian breast screening programmes in 2001 (N=47) and 2014 (N=80). At both times, nearly all programmes provided adequate practical information and details about screening objectives and test procedures. Information regarding epidemiology/figures was scarce or absent in 2001, while in 2014 a number of programmes began to inform women about screening risks (false negative and positive results and overdiagnosis, 65%, 16%, and 21% respectively) although actual figures were rarely supplied. Despite this small improvement, Italian programmes are still far from giving balanced information. Further efforts should be addressed to providing accurate and transparent information, enabling women to make an informed choice.


Assuntos
Neoplasias da Mama/diagnóstico , Mamografia , Neoplasias da Mama/epidemiologia , Detecção Precoce de Câncer , Feminino , Humanos , Incidência , Itália , Mamografia/estatística & dados numéricos , Programas de Rastreamento , Sociedades Médicas
9.
Epidemiol Prev ; 36(6 Suppl 1): 28-38, 2012.
Artigo em Italiano | MEDLINE | ID: mdl-23293269

RESUMO

Since its establishment in 1990, one of the main tasks of the Italian group for breast cancer screening (GISMa) is the systematic data collection on the activity of the organised breast cancer screening programmes implemented in Italy. Data are collected in an aggregated way and gathered through a standardised form to calculate process and impact parameters. Data analysis from 2000-2010 shows that crude attendance rate reached the acceptable 50% standard, presenting a higher level of participation in Northern and Central Italy compared to Southern Italy/Islands, where attendance rates are still inadequate and do not reach the acceptable standard. In areas where a more complete regional extension (referring frequently to a more centralised management) exists, the participation rate was higher compared to those with partial regional extension and no centralised management. The differences range from 5% in 2005 to 22% in 2010. The time trends of the other analysed parameters showed, in 2010, a good overall quality of the performance. For example, benign/malignant surgical biopsy ratio (B/M ratio) reached 0.19 at first screening and 0.11 at subsequent screening; detection rate for in situ and small cancers (≤10 mm) showed a good trend, reaching 0.9‰ and 1.2‰, respectively, at first screening, and 0.6‰, and 1.5‰ for subsequent screening, respectively. On the contrary, excess referral rate at first screening persisted (9.2%) in the year 2010, while RR is improved at subsequent screening (from 4.2% in 2009 to 3.9% in 2010). The overall detection rate is improved both at first and subsequent screening (5.2‰ in 2010 vs. 5.7‰ in 2009 and 4.7‰ in 2010 vs. 5.7‰ in 2009, respectively). Although further analyses are needed to better interpret these trends, results continue to be consistent with those achieved by other European programmes, and they are reassuring for all Italian breast cancer screening professionals.


Assuntos
Neoplasias da Mama/diagnóstico , Carcinoma in Situ/diagnóstico , Mamografia , Programas de Rastreamento/tendências , Avaliação de Processos em Cuidados de Saúde/tendências , Indicadores de Qualidade em Assistência à Saúde/tendências , Idoso , Biópsia/estatística & dados numéricos , Neoplasias da Mama/epidemiologia , Neoplasias da Mama/patologia , Neoplasias da Mama/prevenção & controle , Carcinoma in Situ/epidemiologia , Carcinoma in Situ/patologia , Carcinoma in Situ/prevenção & controle , Detecção Precoce de Câncer/tendências , Feminino , Inquéritos Epidemiológicos , Humanos , Incidência , Itália/epidemiologia , Mamografia/normas , Mamografia/estatística & dados numéricos , Mamografia/tendências , Programas de Rastreamento/normas , Pessoa de Meia-Idade , Participação do Paciente/estatística & dados numéricos , Participação do Paciente/tendências , Encaminhamento e Consulta/tendências , Fatores de Tempo
10.
Eur J Public Health ; 22(3): 413-8, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21746751

RESUMO

BACKGROUND: Several factors can influence access to population breast cancer screening. The aim of the study was to evaluate the impact of different information approaches, women's socio-demographic characteristics and organizational factors on mammography screening uptake. METHODS: We selected 5744 women aged 40-45 years who were randomly assigned to be given letters with: (i) a pre-fixed appointment plus standard leaflet (Group 1); (ii) a pre-fixed appointment plus a more comprehensive booklet (Group 2); (iii) point (ii) plus the offer of a counselling session (Group 3); and (iv) an invitation to contact the centre to get information and arrange participation (Group 4). RESULTS: Ninety-five women were excluded before the invitation and 5649 were randomized. After excluding undelivered letters (n = 41) and women reporting an exclusion criterion following our invitation (n = 248), the final eligible population was 5360 women. Participation rates following the first contact were 36.5, 39.9, 35.8 and 16.5% for Groups 1-4, respectively. The rates increased to 40.9, 43.6, 40.1 and 35.1% after the reminder letters. Women receiving more complete information had a higher uptake (Group 2), although not statistically significant. Differences among the four groups were maintained by controlling the effect of socio-demographic and attendance determinants. Regardless of intervention, participation was higher among married, higher educated, white-collared women, those born in northern Italy, living closer to the screening unit and with a female-collaborative doctor. CONCLUSION: Invitation letters with a fixed appointment correlate with a higher attendance rate. Providing women with more information on procedures, risks and benefits of mammography screening does not modify their participation.


Assuntos
Neoplasias da Mama/diagnóstico , Comunicação , Detecção Precoce de Câncer/estatística & dados numéricos , Mamografia/estatística & dados numéricos , Educação de Pacientes como Assunto/estatística & dados numéricos , Adulto , Agendamento de Consultas , Neoplasias da Mama/diagnóstico por imagem , Neoplasias da Mama/prevenção & controle , Detecção Precoce de Câncer/métodos , Feminino , Humanos , Mamografia/métodos , Pessoa de Meia-Idade , Educação de Pacientes como Assunto/métodos , Fatores Socioeconômicos , Meios de Transporte
11.
Epidemiol Prev ; 35(5-6 Suppl 5): 28-38, 2011.
Artigo em Inglês, Italiano | MEDLINE | ID: mdl-22166348

RESUMO

Since its establishment in 1990, one of the main tasks of the Italian group for mammography screening (GISMa) is the systematic data collection on the activity of the organised mammography screening programmes implemented in Italy. Data are collected in an aggregated way and gathered through a standardised form to calculate process and impact parameters. Data analysis from 1999-2009 shows that crude attendance rate reached the acceptable 50% standard, presenting a higher level of participation in northern and central Italy compared to southern Italy/Islands, where attendance rates are still inadequate and do not reach the acceptable standard. In areas where centralised management is more established or complete, the participation rate was higher compared to areas without such characteristics, with differences from 5% in 2005 (reaching 22% in 2008) to 10% in 2009. The time trends of the other parameters included in the analysis showed, in 2009, a good average performance. For example, benign/malignant surgical biopsy ratio (B/M ratio) reached 0.21 at first screening and 0.08 at subsequent screening; detection rate for in situ and small cancers (≤10 mm) showed a good trend, reaching 0.9‰, and 1.5‰, respectively, for first screening, and 0.9‰, and 1.4‰ for subsequent screening. On the contrary, excess referral rate at first screening persisted, and the overall detection rate presented a negative trend in the last period (8.9% and 5.7‰, respectively). Although further analyses are needed to better interpret these trends, results continue to be consistent with those achieved by other European programmes, and are reassuring for all Italian mammography screening professionals.


Assuntos
Biópsia , Neoplasias da Mama/diagnóstico , Carcinoma in Situ/diagnóstico , Mamografia/estatística & dados numéricos , Programas de Rastreamento/tendências , Algoritmos , Biópsia/estatística & dados numéricos , Neoplasias da Mama/epidemiologia , Carcinoma in Situ/epidemiologia , Feminino , Humanos , Incidência , Itália/epidemiologia , Mamografia/tendências , Encaminhamento e Consulta , Fatores de Tempo
12.
Epidemiol Prev ; 34(5-6 Suppl 4): 27-34, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-21220835

RESUMO

Since its establishment in 1990, one of the main tasks of the Italian Group for Mammography Screening (GISMa) is the systematic data collection on the activity of the organised mammography screening programmes implemented in Italy. Data are collected in an aggregated way and gathered through a standardised form to calculate process and impact parameters. Data analysis referring to the period 1998-2008 shows that crude attendance rate reached the acceptable 50% standard, presenting a higher level of participation in Northern and Central Italy compared to Southern Italy/Islands, where attendance rates are still inadequate and do not reach the acceptable standard. In areas where the centralised management is more established or complete, the participation rate was higher compared with areas without such characteristics, with differences from 5% to 22% (in 2008). The time trends of the other parameters included in the analysis showed, in 2008, a good average performance. For example, benign/malignant surgical biopsy ratio (B/M ratio) reached 0.21 at first screening and 0.11 at subsequent screening; overall detection rate, detection rate for in situ and small cancers (≤10 mm) showed a good trend, reaching 5.7‰, 1.1‰, and 1.4‰, respectively, for first screening, and 5.0‰, 0.7‰, and 1.4‰ for subsequent screening. On the contrary, excess referral rate at first screening persists over time. These results continue to be consistent with those achieved by other European programmes and reassuring for all Italian mammography screening professionals.


Assuntos
Neoplasias da Mama/diagnóstico por imagem , Mamografia/estatística & dados numéricos , Programas de Rastreamento/estatística & dados numéricos , Feminino , Humanos , Itália , Cooperação do Paciente/estatística & dados numéricos , Encaminhamento e Consulta/estatística & dados numéricos , Fatores de Tempo
13.
Epidemiol Prev ; 33(3 Suppl 2): 29-39, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19776485

RESUMO

Since its establishment in 1990, one of the main tasks of the Italian Group for Mammography Screening (GISMa) has been that of collecting, as systematically and thoroughly as possible, data on the activity of the Italian mammography screening programmes. Data are collected in an aggregated way and gathered through a standardised form to calculate process and impact parameters. Analysis of data referring to the period 1998-2007 shows that crude attendance rate reached the acceptable 50% standard, presenting a higher level of participation in Northern and Central Italy compared to Southern Italy/Islands, where attendance rates are still inadequate and do not reach the acceptable standard. In areas where the centralised management is more established or complete, the participation rate was higher compared with areas without such characteristics, with differences of about 4-9%. The time trends of the other parameters included in the analysis showed a good average performance. For example, benign/malignant surgical biopsy ratio (B/M ratio) continued to progressively decrease, reaching 0.20 at first screening and 0.10 at subsequent screening in 2007; overall detection rate, detection rate for in situ and small cancers (< or =10 mm) showed a good trend, reaching 5.4 per thousand, 0.9 per thousand, and 1.6 per thousand, respectively, for fi rst screening, and 4.8 o/oo, 0.8 o/oo, and 1.2 o/oo for subsequent screening in 2007. On the contrary, excess referral rate at first screening persists over time. Data comparing activity volume and programme duration were also considered. In programmes with greater activity volume (average test number: 24,596) the referral rate for first screening was higher if compared with programmes with lower activity volume, but still within acceptable standards. Nevertheless, this performance is compensated by better specificity and sensitivity. An improvement in quality with the increase of programmes experience continues to be evident: compared with new programmes, programmes with more than 6 years of activity showed lower recall rates, higher positive predictive values and higher overall detection rates in the first screening round. Outcomes related to subsequent screening rounds present analogous performances. These results continue to be consistent with those achieved by other European programmes and reassuring for all Italian mammography screening professionals.


Assuntos
Neoplasias da Mama/diagnóstico , Carcinoma in Situ/diagnóstico , Mamografia/tendências , Programas de Rastreamento/tendências , Biópsia , Mama/patologia , Neoplasias da Mama/patologia , Neoplasias da Mama/prevenção & controle , Carcinoma in Situ/patologia , Feminino , Humanos , Itália , Prognóstico , Encaminhamento e Consulta , Fatores de Tempo
14.
Epidemiol Prev ; 30(1 Suppl 3): 17-26, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16937843

RESUMO

Since 1992, the Italian Group for Mammography Screening (GISMa) has been performing a yearly systematic survey of ongoing activities. The screening extension increased from 1996, reaching an overall 68.7% coverage in 2004. This progression has been more evident in Central-Northern Italy while in Southern Italy a real, but still limited (30%), increase has been recorded only recently. Despite this geographical extension, the actual coverage reached only 5 1.1% of the target population, due to a reduced flow of invitations over time as a consequence of a chronic lack of invested resources and of well planned political actions. The time trends for the key performance indicators show a good average performance: crude attendance rate exceeds over the years the acceptable 50% standard; BIM ratio is progressively decreasing, reaching a ratio of 0.7:1 (both for first/subsequent screening) in 2003; overall detection rate, detection rate for in situ and small cancers (< or =10 mm) show a good trend, reaching 6.6% per hundred, 1.5% per hundred and 0.7% per hundred respectively for the first screening in 2003. An exception is the referral rate at first screening which exceeds the reference standards (> 7% in the last 2 years). Data have been analysed also according to activity volume and programme duration. In programmes with greater activity (average test number: 24,702) the referral rate for the first screening is higher, but still within acceptable standards: 5.8%; RR: 1.05 (1.02-1.10). This performance is compensated by better specificity and sensitivity: PPV = 13.3: RR: 1.14 (1.03-1.27); overall detection rate = 6.7% per hundred; RR: 1.22 (1.09-1.36). An improvement of quality with the increase of experience is evident: programmes with more than 6 years of activity, compared with newer programmes, show a recall rate in first screening of 6.0%; RR:0.86 (0.86-0.92), a PPV of 13.4; RR: 1.65 (1.40-1.69) and an overall detection rate of 8.1% per hundred; RR: 1.44 (1.25-1.53). These results are consistent with those observed in other European programmes, and encourage new analysis strategies. The web site of the National Centre for Monitoring Screening is http://wwuw.osservatoriotumori.it.


Assuntos
Neoplasias da Mama/diagnóstico , Carcinoma in Situ/diagnóstico , Mamografia/tendências , Programas de Rastreamento/tendências , Idoso , Neoplasias da Mama/epidemiologia , Carcinoma in Situ/epidemiologia , Feminino , Inquéritos Epidemiológicos , Humanos , Incidência , Itália/epidemiologia , Pessoa de Meia-Idade , Encaminhamento e Consulta/tendências
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