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2.
Actas dermo-sifiliogr. (Ed. impr.) ; 107(7): e52-e56, sept. 2016. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-155540

RESUMO

Las metástasis cutáneas de cáncer de próstata son extremadamente infrecuentes. Presentamos 2 casos de metástasis cutáneas a distancia de adenocarcinoma de próstata, con localización atípica y destacando 2 tinciones inmunohistoquímicas que pueden ayudar al diagnóstico (fosfatasa ácida prostática y el antígeno prostático específico de membrana prostática), fundamentalmente en aquellos casos en los que el antígeno prostático específico es negativo


Cutaneous metastases of prostate cancer are extremely rare. We present 2 cases of distant cutaneous metastases at atypical locations of prostate adenocarcinoma, and highlight the value of 2 immunohistochemical stains-prostatic acid phosphatase and prostate-specific membrane antigen-that can aid diagnosis, particularly in cases with negative staining for prostate-specific antigen


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Idoso de 80 Anos ou mais , Neoplasias da Próstata/complicações , Neoplasias da Próstata/diagnóstico , Neoplasias da Próstata/tratamento farmacológico , Antígeno Prostático Específico/análise , Adenocarcinoma/complicações , Adenocarcinoma/tratamento farmacológico , Adenocarcinoma/patologia , Imuno-Histoquímica/métodos , Metástase Neoplásica/diagnóstico , Metástase Neoplásica/tratamento farmacológico , Prostatectomia/métodos , Prostatectomia , Prognóstico , Neoplasias Cutâneas/complicações , Neoplasias Cutâneas/patologia
4.
Actas Dermosifiliogr ; 107(7): e52-6, 2016 Sep.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-27085465

RESUMO

Cutaneous metastases of prostate cancer are extremely rare. We present 2 cases of distant cutaneous metastases at atypical locations of prostate adenocarcinoma, and highlight the value of 2 immunohistochemical stains-prostatic acid phosphatase and prostate-specific membrane antigen-that can aid diagnosis, particularly in cases with negative staining for prostate-specific antigen.


Assuntos
Adenocarcinoma/secundário , Neoplasias da Próstata/patologia , Neoplasias Cutâneas/secundário , Adenocarcinoma/patologia , Idoso , Idoso de 80 Anos ou mais , Humanos , Masculino , Neoplasias Cutâneas/patologia
5.
Clin Exp Dermatol ; 34(8): e716-8, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19663855

RESUMO

Treatment of eruptive vellus hair cysts (EVHC) is often unsatisfactory. Laser treatment has been described as an adequate treatment in a few reports. Pulsed carbon dioxide (CO(2)) laser has been used effectively for facial EVHC and erbium:yttrium-aluminium-garnet laser has been used to treat truncal EVHC with variable outcomes. We report our experience with CO(2) laser and lateral manual pressure to extract the cysts as an effective treatment in two cases of EVHC. Good cosmetic results were obtained in both cases. No lesion recurrence was observed after a follow-up of 10 years in the first case and 3 years in the second one. CO(2) laser vaporization and further extraction of cysts by manual lateral pressure might be an effective method to treat EVHC, achieving good cosmetic results and no recurrence.


Assuntos
Cisto Epidérmico/cirurgia , Doenças do Cabelo/cirurgia , Folículo Piloso/cirurgia , Lasers de Gás/uso terapêutico , Adulto , Cisto Epidérmico/patologia , Doenças do Cabelo/patologia , Folículo Piloso/patologia , Humanos , Masculino , Pressão
8.
Lupus ; 16(9): 741-5, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17728369

RESUMO

The term "Acute Syndrome of Apoptotic Pan-Epidermolysis" (ASAP) designs clinical entities characterized by massive cleavage of the epidermis resulting from hyperacute epidermal basal cell apoptotic injury. It can be seen typically in classic toxic epidermal necrolysis (TEN), but occasionally occurs in non-drug-induced entities called "TEN-like" diseases (e.g., lupus erythematosus (LE), acute graft versus host disease and pseudoporphyria). We would like to highlight the difficulties of establishing differential diagnoses between "TEN-like" LE and drug reactions, especially when LE has not been previously diagnosed. We report a patient with fulminate pattern of epidermal cell injury resulting in a clinical presentation having combined features of drug-induced TEN and acute cutaneous LE with laboratory findings of systemic LE (SLE) and without systemic symptoms or high-risk drug ingestion. Although most cases of ASAP in the setting of LE are drug-induced TEN, there are reported cases of "TEN-like" LE with subacute progression, absence of systemic involvement and lack of drug ingestion. Such cases usually have a previous history of SLE and positive serologic markers. Although some authors observed that these lesions could be related to systemic severity of SLE, this is the first patient reported who progresses to discoid LE and we think it could be a marker of good prognosis.


Assuntos
Lúpus Eritematoso Discoide/diagnóstico , Síndrome de Stevens-Johnson/diagnóstico , Doença Aguda , Idoso , Diagnóstico Diferencial , Células Epidérmicas , Epiderme/patologia , Feminino , Humanos , Lúpus Eritematoso Discoide/fisiopatologia , Prognóstico , Síndrome de Stevens-Johnson/fisiopatologia
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