FaST-LMM for Two-Way Epistasis Tests on High-Performance Clusters.

We introduce a version of the epistasis test in FaST-LMM for clusters of multithreaded processors. This new software maintains the sensitivity of the original FaST-LMM while delivering acceleration that is close to linear on 12-16 nodes of two recent platforms, with respect to improved implementation of FaST-LMM presented in an earlier work. This efficiency is attained through several enhancements on the original single-node version of FaST-LMM, together with the development of a message passing interface (MPI)-based version that ensures a balanced distribution of the workload as well as a multigraphics processing unit (GPU) module that can exploit the presence of multiple GPUs per node.

Concurrent and Accurate Short Read Mapping on Multicore Processors.

We introduce a parallel aligner with a work-flow organization for fast and accurate mapping of RNA sequences on servers equipped with multicore processors. Our software, HPG Aligner SA (HPG Aligner SA is an open-source application. The software is available at http://www.opencb.org, exploits a suffix array to rapidly map a large fraction of the RNA fragments (reads), as well as leverages the accuracy of the Smith-Waterman algorithm to deal with conflictive reads. The aligner is enhanced with a careful strategy to detect splice junctions based on an adaptive division of RNA reads into small segments (or seeds), which are then mapped onto a number of candidate alignment locations, providing crucial information for the successful alignment of the complete reads. The experimental results on a platform with Intel multicore technology report the parallel performance of HPG Aligner SA, on RNA reads of 100-400 nucleotides, which excels in execution time/sensitivity to state-of-the-art aligners such as TopHat 2+Bowtie 2, MapSplice, and STAR.

Íleo biliar, una causa infrecuente de oclusión intestinal. Presentación de un caso clínico y revisión de la literatura / Gallstone ileus, a rare cause of intestinal obstruction: report of a case and review of the literature

Resumen: El íleo biliar, es una causa poco frecuente de oclusión intestinal. Representa del 1-4% de los casos de oclusión intestinal mecánica. Debe tenerse en mente en pacientes de edad avanzada con signos y síntomas de oclusión intestinal, antecedentes de litiasis vesicular y cuadros repetitivos de cólico biliar. La sospecha de esta patología y el diagnóstico temprano permiten brindar un tratamiento quirúrgico oportuno. En el siguiente artículo documentamos el abordaje diagnóstico y terapéutico de un caso de íleo biliar.

Abstract: Gallstone ileus is an uncommon cause of intestinal obstruction. It represents the 1-4% cases of mechanical intestinal obstruction. It should be considered in elderly patients with symptoms of intestinal obstruction, a history of gallstones and biliary colic repetitive episodes. The suspicion of this disease and early diagnosis, allow to provide a timely surgical treatment. In the following article we document the diagnosis and treatment of a case of gallstone ileus.

Los hijos e hijas y la percepción de pobreza en hogares caleños / Os filhos e filhas e a percepção de pobreza em famílias de Cali / The children and the perception of poverty in Cali’s household

Al estudiar la pobreza, se ha identificado que los hogares tienen una percepción propia sobre su bienestar, por lo que su medición también se realiza desde lo subjetivo. En el presente trabajo determinamos, con base en la Encuesta de Percepción Ciudadana para Cali del año 2008, que hogares con hijos e hijas menores de 5 años tienen una mayor posibilidad de considerarse pobres, y en los hogares con hijos e hijas entre los 5 y los 17 años de edad, esta probabilidad es menor. Como los hogares que decidieron dejar a sus hijos e hijas menores de 5 años al cuidado de una persona adulta lo hicieron motivados por generar mayores ingresos, recomendamos el fortalecimiento de políticas que permitan mejorarlos, sin restar el tiempo que deben dedicarle a sus hijos e hijas.

Ao estudar a pobreza, se tem identificado que as familias têm uma percepção própria sobre o seu bem-estar. No presente trabalho determinamos, com base na Pesquisa de Percepção Cidadã para Cali (Colombia), no ano de 2008, que familias com filhos e filhas de até 5 anos têm maior possibilidade de se considerarem pobres e, nas familias com filhos e filhas entre 5 e 17 anos de idade, esta probabilidade é menor. Assim como as familias que decidiram deixar seus filhos e filhas menores de 5 anos aos cuidados de uma pessoa adulta, fizeram isso motivados em gerar maior renda. Baseados então nessa pesquisa, o presente trabalho recomenda o fortalecimento de políticas que permitam melhorar a vida dessas famílias, sem, contudo, diminuir a sua renda, nem o tempo que devem dedicar a seus filhos e filhas.

By studying poverty, has been identified that households have their own perception on their welfare so that their measurement is also performed from the subjective. This study determined, based on la Encuesta de Percepción Ciudadana for Cali in the year 2008, households with children under 5 years have seen a greater chance of poor households with children between 5 and 17 years this probability is less. Since households that decided to leave their children under 5 years in the care of an adult were motivated by higher incomes, it is recommended the strengthening of policies to improve them, without diminishing the time that they devote to their children.