[Effect of cyclophosphane on the function and structure of the kidneys]. / Vliianie tsiklofosfana na funktsiiu i strukturu pochek.

In experiments on dogs and rats it has been shown that single administration of cyclophosphane in low doses produces no changes in the renal function or in water-electrolyte metabolism. Material changes in the canalicular apparatus of the kidneys, water-salt equilibrium and organ ultrastructure have been recorded in prolonged administration of the drug.