Improved serodiagnosis of Trypanosoma vivax infections in cattle reveals high infection rates in the livestock regions of Argentina.

Bovine trypanosomosis, caused by Trypanosoma vivax, currently affects cattle and has a significant economic impact in sub-Saharan Africa and South America. The development of new diagnostic antigens is essential to improve and refine existing methods. Our study evaluated the efficacy of two recombinant antigens in detecting specific antibodies in cattle. These antigens are derivatives of an invariant surface glycoprotein (ISG) from T. vivax. A fraction of a previously described antigen (TvY486_0045500), designated TvISGAf, from an African strain was evaluated, and a new ISG antigen from an American isolate, TvISGAm, was identified. The two antigens were expressed as fusion proteins in Escherichia coli: TvISGAf was fused to the MBP-His-tag, and TvISGAm was obtained as a His-tag fused protein. An ELISA evaluation was conducted using these antigens on 149 positive and 63 negative bovine samples. The diagnostic performance was enhanced by the use of a combination of both antigens (referred to as TvISG-based ELISA), achieving a sensitivity of 89.6% and specificity of 93.8%. Following the validation of the TvISG-based ELISA, the seroprevalence of T. vivax infection in 892 field samples from cattle in the central region of Argentina was determined. The mean seroprevalence of T. vivax was 53%, with variation ranging from 21% to 69% among the six departments studied. These results support the use of the TvISG ELISA as a valuable serological tool for the detection and monitoring of T. vivax infection in cattle. Furthermore, we report for the first time the seroprevalence of T. vivax in Argentina, which highlights the widespread endemic nature of the disease in the region. In order to effectively manage the increasing spread of T. vivax in the vast livestock production areas of South America, it is essential to implement consistent surveillance programs and to adopt preventive strategies.

Asociación de los grados de movilidad de la articulación atlanto-occipital con la clasificación de Cormack- Lehane como predictores de una vía aérea pediátrica difícil en pacientes de 0 a 12 años de edad en el Hospital Municipal Boliviano Holandés, 2017 / Association of the degrees of mobility of the atlanto-occipital joint with the Cormack-Lehane classification as predictors of a difficult pediatric airway in patients aged 0 to 12 years at the" Municipal Boliviano Holandés" Hospital, 2017

OBJETIVO. Determinar la asociación que existe entre las valoraciones de la articulación atlantooccipital durante la valoración preanestésica y la valoración del Cormack Lehane durante la intubación para predecir una vía aérea difícil en el paciente pediátrico de 0 a 12 años de edad que ingresaron a quirófano del Hospital Municipal Boliviano Holandés en los meses de agosto a octubre de la Gestión 2017. MATERIAL Y METODOS. Es un diseño observacional descriptivo de corte transversal, en 70 pacientes de 0 a 12 años de edad que siguiendo criterios estrictos de inclusión se evaluó la clasificación de vía aérea difícil pediátrica analizando la concordancia entre la asociación de la valoración de la articulación atlantooccipital con la escala de Cormack-Lehane. RESULTADOS. Se evaluaron pacientes entre 0 a 12 años, la Escala de Bellhouse Dore encontrada fue Grado I 39%, Grado III 29%, Grado II 24% y Grado IV 8% y el Cormack Lehane encontrado es grado I 39%, grado III 29%, grado II 24% y el grado IV 8%. La asociación de ambas escalas determinó como predictor de vía aérea normal al 63%, potencialmente difícil 29% y vía aérea difícil 8%. CONCLUSIÓN. Existe asociación entre las valoraciones de la articulación atlantooccipital durante la valoración preanestesica y la valoración del Cormack Lehane durante la intubación como predictor de una vía aérea difícil en el paciente pediátrico de 0 a 12 años de edad.

OBJECTIVE. To determine the association that exists between the assessments of the atlanto-occipital joint during the preanesthetic assessment and the assessment of the Cormack Lehane during intubation to predict a difficult airway in pediatric patients aged 0 to 12 who were admitted to the Municipal Boliviano Holandés Hospital in the months of August to October of the Management 2017. MATERIAL AND METHODS. It is an observational descriptive crosssectional design, in 70 patients from 0 to 12 years of age who, following strict inclusion criteria, evaluated the classification of pediatric difficult airway, analyzing the concordance between the association of the atlanto-occipital joint assessment with the Cormack-Lehane scale. RESULTS. Patients between 0 to 12 years old were evaluated, the Bellhouse Dore Scale found was Grade I 39%, Grade III 29%, Grade II 24% and Grade IV 8% and the Cormack Lehane found is grade I 39%, grade III 29 %, grade II 24% and grade IV 8%. The association of both scales determined a 63% normal airway as a predictor, 29% potentially difficult and 8% difficult airway. CONCLUSION. There is an association between the assessments of the atlanto-occipital joint during the pre-anesthetic assessment and the assessment of the Cormack Lehane during intubation as a predictor of a difficult airway in pediatric patients 0 to 12 years of age.

Infecciones por bacilos Gram-negativos multirresistentes en neonatología / Multidrug resistant Gram-negative infections in neonatology

Introducción. Las infecciones por bacilos Gram-negativos multirresistentes (BGN-MR) constituyen un problema creciente en las unidades de cuidado intensivo neonatal. El objetivo del estudio fue conocer las características epidemiológicas, clínicas, microbiológicas, evolutivas y los factores de riesgo de infección por BGN-MR resistentes a carbapenemes en el Servicio de Neonatología de un hospital de alta complejidad. Población y método. Se realizó un estudio de cohorte retrospectivo en dicho Servicio, donde se incluyeron los pacientes con infección documentada por BGN-MR del 24/4/2013 al 29/4/2015. Resultados. Se incluyeron 21 pacientes. La mediana de edad gestacional y peso de nacimiento fue 35 semanas y 2070 gramos, respectivamente. Dieciocho pacientes (86 %) tuvieron hemocultivos positivos y el aislamiento microbiológico más frecuente fue Acinetobacter baumannii (17 pacientes, 81 %), seguido por Klebsiella pneumoniae productora de carbapenemasa (3 pacientes, 14 %) y Enterobacter cloacae (1 paciente, 5 %). La mediana de edad al momento del diagnóstico fue de 28 días y todos tenían factores de riesgo para la infección, como cirugía, asistencia respiratoria mecánica, nutrición parenteral, catéter central y antibióticos. El tratamiento antibiótico definitivo fue colistina en todos los casos, combinado en el 84 %. Cinco pacientes (24 %) fallecieron por la infección. La prematurez y el peso < 2000 g fueron factores de riesgo estadísticamente significativos asociados a la mortalidad (p = 0,03 y 0,01, respectivamente). Conclusión. Las infecciones por BGN-MR se presentaron en pacientes con factores predisponentes. Acinetobacter baumannii fue el primer agente etiológico. La mortalidad fue elevada y relacionada con prematurez y bajo peso al nacer.

Introduction. Multidrug resistant Gramnegative (MDRGN) infections are an increasing problem in neonatal intensive care units. The objective of this study was to establish the epidemiological, clinical, microbiological, and evolutionary characteristics of carbapenem-resistant MDRGN infections and the risk factors for them at the Division of Neonatology of a tertiary care hospital. Population and method. A retrospective cohort study was done in this Division in patients with a documented MDRGN infection between 4/24/2013 and 4/29/2015. Results. Twenty-one patients were included. Their median gestational age and birth weight were 35 weeks and 2070 g, respectively. Eighteen patients (86 %) had a positive blood culture; the most commonly isolated microorganism was Acinetobacter baumannii (17 patients, 81 %), followed by carbapenemase-producing Klebsiella pneumoniae (3 patients, 14 %) and Enterobacter cloacae (1 patient, 5 %). The median age at diagnosis was 28 days and all patients had risk factors for infection, including surgery, assisted mechanical ventilation, parenteral nutrition, central venous line, and antibiotics. The definite antibiotic therapy included colistin in all cases; in combination, in 84 %. Five patients (24 %) died due to the infection. Prematurity and a birth weight < 2000 g were statistically significant risk factors associated with mortality (p = 0.03 and 0.01, respectively). Conclusion. MDRGN infections were observed in patients with predisposing factors. Acinetobacter baumannii was the main etiologic agent. Mortality was high and related to prematurity and a low birth weight.

Multidrug resistant Gram-negative infections in neonatology. / Infecciones por bacilos Gram-negativos multirresistentes en neonatología.

INTRODUCTION: Multidrug resistant Gramnegative (MDRGN) infections are an increasing problem in neonatal intensive care units. The objective of this study was to establish the epidemiological, clinical, microbiological, and evolutionary characteristics of carbapenem-resistant MDRGN infections and the risk factors for them at the Division of Neonatology of a tertiary care hospital. POPULATION AND METHOD: A retrospective cohort study was done in this Division in patients with a documented MDRGN infection between 4/24/2013 and 4/29/2015. RESULTS: Twenty-one patients were included. Their median gestational age and birth weight were 35 weeks and 2070 g, respectively. Eighteen patients (86 %) had a positive blood culture; the most commonly isolated microorganism was Acinetobacter baumannii (17 patients, 81 %), followed by carbapenemase-producing Klebsiella pneumoniae (3 patients, 14 %) and Enterobacter cloacae (1 patient, 5 %).The median age at diagnosis was 28 days and all patients had risk factors for infection, including surgery, assisted mechanical ventilation, parenteral nutrition, central venous line, and antibiotics. The definite antibiotic therapy included colistin in all cases; in combination, in 84 %. Five patients (24 %) died due to the infection. Prematurity and a birth weight < 2000 g were statistically significant risk factors associated with mortality (p = 0.03 and 0.01, respectively). CONCLUSION: MDRGN infections were observed in patients with predisposing factors. Acinetobacter baumannii was the main etiologic agent. Mortality was high and related to prematurity and a low birth weight.

Introducción. Las infecciones por bacilos Gram-negativos multirresistentes (BGN-MR) constituyen un problema creciente en las unidades de cuidado intensivo neonatal. El objetivo del estudio fue conocer las características epidemiológicas, clínicas, microbiológicas, evolutivas y los factores de riesgo de infección por BGN-MR resistentes a carbapenemes en el Servicio de Neonatología de un hospital de alta complejidad. Población y método. Se realizó un estudio de cohorte retrospectivo en dicho Servicio, donde se incluyeron los pacientes con infección documentada por BGN-MR del 24/4/2013 al 29/4/2015. Resultados. Se incluyeron 21 pacientes. La mediana de edad gestacional y peso de nacimiento fue 35 semanas y 2070 gramos, respectivamente. Dieciocho pacientes (86 %) tuvieron hemocultivos positivos y el aislamiento microbiológico más frecuente fue Acinetobacter baumannii (17 pacientes, 81 %), seguido por Klebsiella pneumoniae productora de carbapenemasa (3 pacientes, 14 %) y Enterobacter cloacae (1 paciente, 5 %). La mediana de edad al momento del diagnóstico fue de 28 días y todos tenían factores de riesgo para la infección, como cirugía, asistencia respiratoria mecánica, nutrición parenteral, catéter central y antibióticos. El tratamiento antibiótico definitivo fue colistina en todos los casos, combinado en el 84 %. Cinco pacientes (24 %) fallecieron por la infección. La prematurez y el peso < 2000 g fueron factores de riesgo estadísticamente significativos asociados a la mortalidad (p = 0,03 y 0,01, respectivamente). Conclusión. Las infecciones por BGN-MR se presentaron en pacientes con factores predisponentes. Acinetobacter baumannii fue el primer agente etiológico. La mortalidad fue elevada y relacionada con prematurez y bajo peso al nacer.

Capacidad resolutiva del primer nivel de atención: experiencia de la Unidad Docente-Asistencial de Medicina Familiar y Comunitaria de Paysandú (2014) / Resolutivity in the first level of care. An experience in the Teaching Unit Healthcare Service of Family and Community Medicine in Paysandú (2014)

Introducción: la resolutividad del primer nivel de atención (PNA) es una cualidad fundamental de los sistemas de salud porque repercute en el funcionamiento de los otros niveles y en los servicios de urgencia. En nuestro país se ha insistido sobre la necesidad de contar con un PNA resolutivo, sustentado en la sobrecarga asistencial que soportan los servicios del segundo nivel de atención (SNA) y las puertas de emergencia de los hospitales o sanatorios, atribuida, entre otros aspectos, a la baja resolutividad del PNA. Objetivos: evaluar las consultas que requirieron traslado a los servicios de emergencia de la Administración de los Servicios de Salud del Estado (ASSE) o de la Corporación Médica de Paysandú (COMEPA), y las referencias realizadas a especialistas del SNA por la Unidad Docente - Asistencial (UDA) N°74 de Paysandú durante 2014. Método: estudio observacional, descriptivo y de corte realizado en cinco servicios del PNA de Paysandú, usando instrumentos de registro específicos. Resultados: de un total de 8.265 consultas realizadas,75 requirieron traslado al servicio de emergencia (0,9%), predominando en adultos jóvenes, en meses de junio y setiembre, debido principalmente a patologías respiratorias, y requiriendo ambulancia en el 49% de los casos. El 5% (n=415) del total de consultas realizadas fueron derivadas al SNA, predominando en adultos mayores de 45 años, y debido a patologías de ojos y anexos, aparato circulatorio y locomotor. Conclusiones: la resolutividad de la UDA de Medicina Familiar y Comunitaria de Paysandú es alta; se valora especialmente las competencias de dicha disciplina en ese sentido, y es posible mejorarla dotando de mayores recursos materiales al PNA (por ejemplo, oftalmoscopio).

Abstract Introduction: resolutivity in the first level of care is an essential quality of the health system since this has an impact on the other levels of care and on emergency services. In our country, an emphasis has been made on the need for a first level of care that is resolutive, based on the overload borne by the second level of care services and the doors at the emergency rooms in hospitals and private clinics which, among other aspects, results from the low resolutivity of the first level of care. Objectives: to evaluate consultations which required transport to the emergency services of the National Administration of Health Services or the Corporación Médica de Paysandú (COMEPA), and the references made to specialists in the second level of care by the Teaching Unit Healthcare Service N° 74, Paysandú in 2014. Method: observational, descriptive study of a cohort, conducted in five services of the first level of care in Paysandú, using specific recording instruments. Results: out of 8,265 consultations, 75 required transport to the emergency services (0.9%), the majority being young adults, between June and September, mainly due to respiratory conditions, an ambulance being required in 49% of cases. 5% (n=415) of all consultations were referred to the second level of care, most of which were adults over 45 years old, mainly due to eye conditions and associated pathologies, the circulatory and the musculoskeletal systems. Conclusions: resolutivity in the Teaching Unit Healthcare Service of Family and Community Medicine of Paysandú is high, competences in this discipline are highly valued and it can be further improved by allocating greater material resources (an ophtalmoscopy for instance).

Resumo Introdução: a capacidade de resolução do primeiro nível de atenção (PNA) é uma qualidade fundamental dos sistemas de saúde porque tem impacto no funcionamento dos outros níveis e nos serviços de urgência. No nosso país se insiste sobre a necessidade de contar com um PNA resolutivo, considerando a sobrecarga assistencial que suportam os serviços do segundo nível de atenção (SNA) e os pronto-socorro dos hospitais e sanatórios, atribuída, entre outros aspectos, a baixa capacidade de resolução do PNA. Objetivos: avaliar as consultas que demandaram transferência a serviços de emergência de ASSE (Administración de los Servicios de Salud del Estado) ou de COMEPA (Corporación Médica de Paysandu), e as referencias realizadas a especialistas do SNA pela Unidade Docente-Assistencial (UDA) N° 74, Paysandu, durante 2014. Método: estudo observacional, descritivo e de corte, realizado em cinco serviços do PNA de Paysandu, usando instrumentos de registro específicos. Resultados: das 8.265 consultas realizadas, 75 demandaram transferência ao serviço de emergência (0,9%), predominando adultos jovens, nos meses de junho e setembro, devido principalmente a patologias respiratórias, sendo necessário o uso de ambulância em 49%. 5% (n=415) das consultas realizadas foram derivadas ao SNA, predominando adultos com mais de 45 anos, devido a patologias dos olhos e anexos, aparelho circulatório e locomotor. Conclusões: a capacidade de resolução da UDA de Medicina Familiar e Comunitária (MFyC) de Paysandu é alta; destacam-se especialmente as capacidades desta disciplina sendo possível melhorá-la com a inclusão de mais recursos materiais no PNA como, por exemplo, oftalmoscópio.

Variation in the documentation of findings in pediatric voiding cystourethrogram.

BACKGROUND: Few standards exist for reporting results of voiding cystourethrogram (VCUG). OBJECTIVE: To assess the variation in reporting of VCUG findings from different facilities using a standardized assessment tool. MATERIALS AND METHODS: VCUG reports were evaluated for demographic, technical, anatomical and functional information. Reports were categorized by age, gender, indication and vesicouretal reflux (VUR) status. Institutions were classified as a free-standing pediatric hospital (n = 3), pediatric hospital within a hospital (n = 11), or non-pediatric facility (n = 24) and reports were classified as having been read by a pediatric radiologist or not. Each category of outside reports (n = 152) was randomly matched with a twice-larger group of Hospital A reports from the same category (n = 304). Multivariate linear regression was used to analyze the association between the primary outcome (percentage of items described in dictated VCUG report) and the type of radiologist and institution. RESULTS: Of the 456 studies, 66% were in girls, 56% were in those <12 months old, and the indication was urinary tract infection (UTI) in 81%. The mean percentage of items reported was 67 ± 14% (74 ± 7% at free-standing pediatric hospitals, 61 ± 10% at pediatric hospitals within a hospital, and 48 ± 11% at non-pediatric facilities). In multivariate analysis, VCUG reports generated at non-pediatric facilities had 17% fewer items included (95% CI: 14.5-19.7%, P < 0.0001), and pediatric hospitals within a hospital had 9% fewer items included (5.9-12.5%, P < 0.0001) when compared to free-standing pediatric hospitals. Reports read by a pediatric radiologist had 12% more items included (9.1-15.3%, P < 0.0001) compared to those read by a non-pediatric radiologist. CONCLUSION: More complete VCUG reports were observed when generated at free-standing pediatric hospitals and when interpreted by a pediatric radiologist.

[Ocular involvement in congenital Chagas disease]. / Compromiso ocular en la enfermedad de Chagas congénita: Cases report.

Ophthalmic compromise is infrequent in children with congenital Chagas disease. We present 3 patients under 2 months of age, with ocular involvement, all of them referred to the hospital for ophthalmic evaluation of the premature newborn. The ophthalmic finding was bilateral severe vitreitis (posterior uveitis) related to Chagas disease. They received antiparasitic therapy with a good outcome in all cases. Chagas disease must be considered as differential diagnosis of ocular pathology in those countries where the pathology is endemic, and fundoscopic evaluation must be done in those children with the diagnosis, especially those symptomatic and prematurely born.

Compromiso ocular en la enfermedad de Chagas congénita: Cases report / Ocular involvement in congenital Chagas disease

El compromiso ocular es una forma de presentación infrecuente en los niños con la enfermedad de Chagas congénita. Se presentan tres pacientes menores de dos meses de edad con compromiso ocular, todos ellos derivados al hospital para control oftalmológico por prematuridad. El diagnóstico oftalmológico fue de vitreítis bilateral intensa (uveítis posterior) asociada a enfermedad de Chagas. Se realizó tratamiento antiparasitario, con buena respuesta en los tres casos. Debe considerarse la enfermedad de Chagas como diagnóstico diferencial de una patología ocular en los lugares donde la enfermedad es endémica y solicitar una evaluación oftalmológica en los niños con diagnóstico de la enfermedad, en especial aquellos sintomáticos y con antecedente de prematuridad.(AU)

Ophthalmic compromise is infrequent in children with congenital Chagas disease. We present 3 patients under 2 months of age, with ocular involvement, all of them referred to the hospital for ophthalmic evaluation of the premature newborn. The ophthalmic finding was bilateral severe vitreitis (posterior uveitis) related to Chagas disease. They received antiparasitic therapy with a good outcome in all cases. Chagas disease must be considered as differential diagnosis of ocular pathology in those countries where the pathology is endemic, and fundoscopic evaluation must be done in those children with the diagnosis, especially those symptomatic and prematurely born.(AU)

Compromiso ocular en la enfermedad de Chagas congénita: Cases report / Ocular involvement in congenital Chagas disease

El compromiso ocular es una forma de presentación infrecuente en los niños con la enfermedad de Chagas congénita. Se presentan tres pacientes menores de dos meses de edad con compromiso ocular, todos ellos derivados al hospital para control oftalmológico por prematuridad. El diagnóstico oftalmológico fue de vitreítis bilateral intensa (uveítis posterior) asociada a enfermedad de Chagas. Se realizó tratamiento antiparasitario, con buena respuesta en los tres casos. Debe considerarse la enfermedad de Chagas como diagnóstico diferencial de una patología ocular en los lugares donde la enfermedad es endémica y solicitar una evaluación oftalmológica en los niños con diagnóstico de la enfermedad, en especial aquellos sintomáticos y con antecedente de prematuridad.

Ophthalmic compromise is infrequent in children with congenital Chagas disease. We present 3 patients under 2 months of age, with ocular involvement, all of them referred to the hospital for ophthalmic evaluation of the premature newborn. The ophthalmic finding was bilateral severe vitreitis (posterior uveitis) related to Chagas disease. They received antiparasitic therapy with a good outcome in all cases. Chagas disease must be considered as differential diagnosis of ocular pathology in those countries where the pathology is endemic, and fundoscopic evaluation must be done in those children with the diagnosis, especially those symptomatic and prematurely born.

[Staphylococcus aureus methicillin-resistant community acquired neonatal orbital cellulitis]. / Celulitis orbitaria neonatal por Staphylococcus aureus meticilinorresistente de la comunidad.

Orbital cellulitis typically occurs in older children, but it can occasionally affect infants and neonates. Staphylococcus aureus is the main pathogen isolated. Outcome depends on an adequate initial approach. We report three neonates with orbital cellulitis caused by community-associated MRSA.

Celulitis orbitaria neonatal por Staphylococcus aureus meticilinorresistente de la comunidad / Staphylococcus aureus methicillin-resistant community acquired neonatal orbital cellulitis

La celulitis orbitaria es una patología del niño mayor y raramente compromete al período neonatal. Staphylococcus aureus (SA) es el principal agente etiológico relacionado. El diagnóstico precoz y el tratamiento adecuado mejoran el pronóstico. Se presentan tres recién nacidos con celulitis orbitaria por SA meticilinorresistente de la comunidad (SAMR-CO).(AU)

Orbital cellulitis typically occurs in older children, but it can occasionally affect infants and neonates. Staphylococcus aureus is the main pathogen isolated. Outcome depends on an adequate initial approach. We report three neonates with orbital cellulitis caused by community- associated MRSA.(AU)

Celulitis orbitaria neonatal por Staphylococcus aureus meticilinorresistente de la comunidad / Staphylococcus aureus methicillin-resistant community acquired neonatal orbital cellulitis

La celulitis orbitaria es una patología del niño mayor y raramente compromete al período neonatal. Staphylococcus aureus (SA) es el principal agente etiológico relacionado. El diagnóstico precoz y el tratamiento adecuado mejoran el pronóstico. Se presentan tres recién nacidos con celulitis orbitaria por SA meticilinorresistente de la comunidad (SAMR-CO).

Orbital cellulitis typically occurs in older children, but it can occasionally affect infants and neonates. Staphylococcus aureus is the main pathogen isolated. Outcome depends on an adequate initial approach. We report three neonates with orbital cellulitis caused by community- associated MRSA.

Celulitis orbitaria neonatal por Staphylococcus aureus meticilinorresistente de la comunidad. / [Staphylococcus aureus methicillin-resistant community acquired neonatal orbital cellulitis].

Orbital cellulitis typically occurs in older children, but it can occasionally affect infants and neonates. Staphylococcus aureus is the main pathogen isolated. Outcome depends on an adequate initial approach. We report three neonates with orbital cellulitis caused by community-associated MRSA.

Compromiso ocular en la enfermedad de Chagas congénita: Cases report. / [Ocular involvement in congenital Chagas disease].

Ophthalmic compromise is infrequent in children with congenital Chagas disease. We present 3 patients under 2 months of age, with ocular involvement, all of them referred to the hospital for ophthalmic evaluation of the premature newborn. The ophthalmic finding was bilateral severe vitreitis (posterior uveitis) related to Chagas disease. They received antiparasitic therapy with a good outcome in all cases. Chagas disease must be considered as differential diagnosis of ocular pathology in those countries where the pathology is endemic, and fundoscopic evaluation must be done in those children with the diagnosis, especially those symptomatic and prematurely born.

[Staphylococcus aureus methicillin-resistant community acquired neonatal orbital cellulitis]. / Celulitis orbitaria neonatal por Staphylococcus aureus meticilinorresistente de la comunidad.

Orbital cellulitis typically occurs in older children, but it can occasionally affect infants and neonates. Staphylococcus aureus is the main pathogen isolated. Outcome depends on an adequate initial approach. We report three neonates with orbital cellulitis caused by community-associated MRSA.

Celulitis orbitaria neonatal por Staphylococcus aureusmeticilinorresistente de la comunidad / Staphylococcus aureus methicillin-resistant community acquired neonatal orbital cellulitis

La celulitis orbitaria es una patología del niño mayor y raramente compromete al período neonatal. Staphylococcus aureus(SA) es el principal agente etiológico relacionado. El diagnóstico precoz y el tratamiento adecuado mejoran el pronóstico.Se presentan tres recién nacidos con celulitis orbitaria por SAmeticilinorresistente de la comunidad (SAMR-CO) (AU)

Celulitis orbitaria neonatal por Staphylococcus aureusmeticilinorresistente de la comunidad / Staphylococcus aureus methicillin-resistant community acquired neonatal orbital cellulitis

La celulitis orbitaria es una patología del niño mayor y raramente compromete al período neonatal. Staphylococcus aureus(SA) es el principal agente etiológico relacionado. El diagnóstico precoz y el tratamiento adecuado mejoran el pronóstico.Se presentan tres recién nacidos con celulitis orbitaria por SAmeticilinorresistente de la comunidad (SAMR-CO) (AU)

Celulitis orbitaria neonatal por Staphylococcus aureusmeticilinorresistente de la comunidad / Staphylococcus aureus methicillin-resistant community acquired neonatal orbital cellulitis

La celulitis orbitaria es una patología del niño mayor y raramente compromete al período neonatal. Staphylococcus aureus(SA) es el principal agente etiológico relacionado. El diagnóstico precoz y el tratamiento adecuado mejoran el pronóstico.Se presentan tres recién nacidos con celulitis orbitaria por SAmeticilinorresistente de la comunidad (SAMR-CO)

Osteoarthritis in the neonate: risk factors and outcome.

OBJECTIVES: The aim of this study was to identify the clinical, radiological, and bacteriological features, risk factors, and outcome of neonates with bone and joint infections. STUDY DESIGN: Observational, retrospective, and analytical study of 77 patients less than 2 months of age, admitted to a tertiary neonatal intensive care unit (NICU) with the diagnosis of bone or joint infection, based on clinical, radiological, and microbiological criteria. RESULTS: Seventy-seven patients with 99 acute osteoarthritis foci in a 16 year period were included in the study. Risk factors for infection could be identified in 69% of the patients. The hip was the most frequent. Staphylococcus aureus was the main isolated microorganism. Twenty-nine infants (38%) had sequelae. Hip involvement, culture positive, and Staphylococcus aureus isolation were risk factors associated with sequelae. CONCLUSION: Osteoarticular infection is unusual in the neonate; however it is associated with an elevated incidence of sequelae. This mandates for a high degree of suspicion to diagnose this potentially disabling entity.

Osteoarthritis in the neonate: risk factors and outcome

OBJECTIVES: The aim of this study was to identify the clinical, radiological, and bacteriological features, risk factors, and outcome of neonates with bone and joint infections. STUDY DESIGN: Observational, retrospective, and analytical study of 77 patients less than 2 months of age, admitted to a tertiary neonatal intensive care unit (NICU) with the diagnosis of bone or joint infection, based on clinical, radiological, and microbiological criteria. RESULTS: Seventy-seven patients with 99 acute osteoarthritis foci in a 16 year period were included in the study. Risk factors for infection could be identified in 69 percent of the patients. The hip was the most frequent. Staphylococcus aureus was the main isolated microorganism. Twenty-nine infants (38 percent) had sequelae. Hip involvement, culture positive, and Staphylococcus aureus isolation were risk factors associated with sequelae. CONCLUSION: Osteoarticular infection is unusual in the neonate; however it is associated with an elevated incidence of sequelae. This mandates for a high degree of suspicion to diagnose this potentially disabling entity.