RESUMO
Six patients are reported in whom systemic lupus erythematosus (SLE) and thyrotoxicosis coexisted. All had four or more American Rheumatism Association criteria (1982) for the diagnosis of SLE and had clinical manifestations and function test results characteristic of hyperthyroidism (except for one who had been thyroidectomised previously). In three patients the diagnosis of hyperthyroidism preceded that of SLE, in two patients both diseases began simultaneously, and only in one was the diagnosis of thyrotoxicosis made after that of SLE. It is suggested that hyperthyroidism associated with SLE may be a form of presentation of thyroiditis. This association may pass unnoticed because of the similarity of some clinical manifestations.
Assuntos
Doença de Graves/complicações , Lúpus Eritematoso Sistêmico/complicações , Adulto , Feminino , Doença de Graves/diagnóstico , Humanos , Lúpus Eritematoso Sistêmico/diagnóstico , Fatores de TempoRESUMO
When she was five years old, this patient - aged 20 time of death - had had two diagnoses: Leri-Weill's disease and SLE. The latter led to uninterrupted use of systemic corticosteroids. Twelve months before death, multiple purulent bursitis were followed by cutaneous nodules. From the latter, but not from the former, Mycobacterium fortuitum was isolated. Our case is in agreement with what is generally accepted: this saprophyte organism becomes pathogenic in disseminated infections, only if the immune system deteriorates.
