RESUMO
Phytochemical analysis of the root bark of Bauhinia variegata Linn yielded a new flavanone, (2S)-5,7-dimethoxy-3',4'-methylenedioxyflavanone (1) and a new dihydrodibenzoxepin, 5,6-dihydro-1,7-dihydroxy-3,4-dimethoxy-2-methyldibenz [b,f]oxepin (2) together with three known flavonoids (3-5). The structures of the new compounds were determined on the basis of spectral studies.
Assuntos
Bauhinia/química , Dibenzoxepinas/química , Dibenzoxepinas/isolamento & purificação , Flavanonas/química , Flavanonas/isolamento & purificação , Espectroscopia de Ressonância Magnética , Estrutura Molecular , Casca de Planta/química , Raízes de Plantas/químicaRESUMO
A new naphthoquinone, 2,7-dihydroxy-8-formyl-5-isopropyl-3-methyl-1,4-naphthoquinone (1) together with a known naphthoquinone, 8-formyl-7-hydroxy-5-isopropyl-2-methoxy-3-methyl-1,4-naphthoquinone (2), has been isolated from the heartwood of Ceiba pentandra. The structures of 1 and 2 have been elucidated by extensive 1D and 2D NMR experiments.
Assuntos
Ceiba/química , Naftoquinonas/isolamento & purificação , Espectroscopia de Ressonância Magnética , Naftoquinonas/químicaRESUMO
Two new flavonoids, 2',4',6',2,3,4-hexamethoxychalcone (1) and 5-hydroxy-7,2',5'-trimethoxyflavone (2) together with a known flavone glycoside, echioidinin 5-O-beta-D-glucopyranoside (3) were isolated from the whole plant of Andrographis neesiana, and the structures were elucidated by electrospray ionization tandem mass spectrometry (ESI-MS/MS) and one- and two-dimensional (1D- and 2D)-NMR spectral studies including 1H-1H correlation spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond connectivity (HMBC) and nuclear Overhauser enhancement spectroscopy (NOESY) experiments.
Assuntos
Andrographis , Chalcona/química , Chalcona/isolamento & purificação , Flavonoides/química , Flavonoides/isolamento & purificação , Extratos Vegetais/química , Extratos Vegetais/isolamento & purificação , Estruturas VegetaisRESUMO
Three flavonoids, 5,7,2',3',4'-pentamethoxyflavone (1), 2'-hydroxy-2,4',6'-tri methoxychalcone (2) and dihydroskullcapflavone I (3), together with 17,19,20-trihydroxy-5beta, 8alpha H, 9beta H,10alpha-labd-13-en-16,15-olactone (4), a known diterpenoid and six known flavonoids, 5-hydroxy-7,8-dimethoxyflavanone (5), 5-hydroxy-7,8,2',3',4'-pentamethoxyflavone (6), 5,2'-dihydroxy-7-methoxyflavanone (7), 5,2'-dihydroxy-7,8-dimethoxyflavone (8), 5,2'-dihydroxy-7-methoxyflavone (9) and 5,2'-dihydroxy-7-methoxyflavone 2'-O-beta-D-glucopyranoside (10) were isolated from the whole plant of Andrographis lineata. The structures of these compounds were elucidated on the basis of spectral and chemical studies.
Assuntos
Andrographis/química , Flavonoides/isolamento & purificação , Diterpenos/química , Diterpenos/isolamento & purificação , Flavonoides/química , Análise Espectral/métodosRESUMO
A new sesquiterpene lactone, 5-isopropyl-3-methyl-2,4,7-trimethoxy-8,1-naphthalene carbolactone (1) together with a known naphthoquinone, 8-formyl-7-hydroxy-5-isopropyl-2-methoxy-3-methyl-1,4-naphthoquinone (2) were isolated from the root bark of Bombax malabaricum. The structures of these two compounds were established by extensive one- and two-dimensional (1D- and 2D)-NMR spectral studies.
Assuntos
Bombax , Lactonas/química , Lactonas/isolamento & purificação , Sesquiterpenos/química , Sesquiterpenos/isolamento & purificação , Casca de Planta , Extratos Vegetais/química , Extratos Vegetais/isolamento & purificaçãoRESUMO
Phytochemical investigation of the roots and aerial parts of Andrographis paniculata Nees yielded a new flavone, 5-hydroxy-7,2',6'-trimethoxyflavone and an unusual 23-carbon terpenoid, 14-deoxy-15-isopropylidene-11,12-didehydroandrographolide together with five known flavonoids and four known diterpenoids. The structures of these compounds were determined on the basis of spectral and chemical studies.
Assuntos
Andrographis/química , Flavonoides/química , Flavonoides/isolamento & purificação , Terpenos/química , Terpenos/isolamento & purificação , Alcenos/química , Cromatografia em Gel , Ressonância Magnética Nuclear Biomolecular , Estruturas Vegetais/química , Espectrometria de Massas por Ionização por Electrospray/métodosRESUMO
Three new 2'-oxygenated flavonoids, (2S)-5,7,2',3',4'-pentamethoxyflavanone (1), 5-hydroxy-7,8,2',5'-tetramethoxyflavone (2), and echioidinin 2'-O-beta-d-(6' '-O-acetyl) glucopyranoside (3), together with four known flavonoids, 7-O-methyldihydrowogonin, 7-O-methylwogonin, skullcapflavone I 2'-methyl ether, and skullcapflavone I, and two diterpenoids, andrograpanin and 14-deoxy-11,12-didehydroandrographolide, were isolated from the whole plant of Andrographis affinis. The structures were elucidated by spectral and chemical studies.
Assuntos
Andrographis/química , Flavanonas , Flavonoides/isolamento & purificação , Dicroísmo Circular , Diterpenos/química , Diterpenos/isolamento & purificação , Flavonoides/química , Glucosídeos/química , Glucosídeos/isolamento & purificação , Hidrólise , Índia , Estrutura Molecular , Ressonância Magnética Nuclear BiomolecularRESUMO
Two new flavonoids, 5, 7, 2', 5'-tetramethoxyflavanone (1) and 5-hydroxy-7, 2'-dimethoxyflavone (2), together with two known flavones, skullcapflavone I (3) and echioidin (4) were isolated from the whole plant of Andrographis rothii. The structures of the new compounds were established by extensive one- and two-dimensional (1D- and 2D-) NMR spectral studies.
Assuntos
Andrographis , Flavonoides/química , Flavonoides/isolamento & purificação , Extratos Vegetais/química , Extratos Vegetais/isolamento & purificação , Estruturas VegetaisRESUMO
A new coumestan, tephcalostan (1) has been isolated from the whole plant of Tephrosia calophylla BEDD. together with two known flavonoids, 7-O-methylglabranin (2) and kaempferol 3-O-beta-D-glucopyranoside (3). The structure of tephcalostan was elucidated as 5'-(R)-8, 9-methylenedioxy-5'-isopropenyl-4', 5'-dihydrofurano[2', 3':2, 3]coumestan by extensive one-and two-dimensional (1D- and 2D-)-NMR techniques including (1)H-(1)H correlation spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond connectivity (HMBC) and nuclear Overhauser enhancement spectroscopy (NOESY) experiments.
Assuntos
Cumarínicos/química , Cumarínicos/isolamento & purificação , Tephrosia , Flavonoides/química , Flavonoides/isolamento & purificação , Extratos Vegetais/química , Extratos Vegetais/isolamento & purificação , Estruturas VegetaisRESUMO
Two new 5-deoxyflavones, 7,8-dimethoxy-3',4'-methylenedioxyflavone (1) and 7,2',4'-trimethoxyflavone (2) together with a known flavone, 7,4'-dimethoxy-3'-hydroxyflavone (3) were isolated from the rootbark of Albizia odoratissima. The structures of these new compounds were elucidated by electrospray ionization mass spectrometry (ESI-MS) and 1D and 2D-NMR spectral studies including (1)H-(1)H correlation spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond connectivity (HMBC) and nuclear Overhauser enhancement spectroscopy (NOESY).