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Int J Mol Sci ; 18(5)2017 Apr 27.
Artigo em Inglês | MEDLINE | ID: mdl-28448467

RESUMO

Recent research shows variations in pollen chemical constituents and, consequently, in their therapeutic properties. Mono and multifloral bee pollen extracts were investigated for antioxidant and enzyme inhibitory activity properties, phenolic compounds and fatty acid composition. Generally, Eucalyptus spp. and multifloral extracts exhibited potent inhibitory activity against α-amylase, acetylcholinesterase, tyrosinase, lipoxygenase, lipase and hyaluronidase. On the other hand, Miconia spp. demonstrated higher antihemolytic activity. Cocos nucifera and Miconia spp. extracts exhibited important antioxidant properties in the different assays (ABTS, DPPH, ß-carotene/linoleic acid and reducing power). Moreover, these extracts had greater amounts of total phenols and flavonoids in comparison to others. The increase in antioxidant activity (decrease in EC50 values) was accompanied by an increase in the amount of total phenols in the extracts. The pollen extracts contained linoleic acid and α-linolenic acid as major fatty acids, followed by palmitic acid, and oleic acid. In this study, differences were observed in both chemical constituents and biological activities of the samples related to the geographical and botanical origin of bee pollen.


Assuntos
Extratos Vegetais/química , Pólen/química , Acetilcolinesterase/química , Acetilcolinesterase/metabolismo , Animais , Antioxidantes/química , Antioxidantes/metabolismo , Abelhas , Cromatografia Gasosa , Cocos/química , Cocos/metabolismo , Eucalyptus/química , Eucalyptus/metabolismo , Ácidos Graxos/análise , Ácidos Graxos/química , Flavonoides/análise , Flavonoides/química , Melastomataceae/química , Melastomataceae/metabolismo , Monofenol Mono-Oxigenase/antagonistas & inibidores , Monofenol Mono-Oxigenase/metabolismo , Fenóis/análise , Fenóis/química , Extratos Vegetais/metabolismo , Análise de Componente Principal , alfa-Amilases/antagonistas & inibidores , alfa-Amilases/metabolismo
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