1.
Am J Emerg Med
; 35(4): 655, 2017 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28041760
2.
Am J Emerg Med
; 35(1): 144-145, 2017 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27742523
RESUMO
Glucagon, a hormone secreted by pancreatic alpha cells, causes bronchial smooth muscle relaxation by activating the synthesis of cyclic adenosine monophosphate. It was studied in the 1980s and 1990s as a treatment option for the management of asthma but has since not been evaluated. Data to support its use are limited, but it may serve as a last-line agent for refractory asthma exacerbation. Here we describe 4 cases in which intravenous glucagon was used to manage severe, refractory asthma exacerbation in the emergency department.