RESUMO
BACKGROUND: As few population studies exist, the study of positive serological tests detected in laboratory services may be an acceptable approximation for the assessment of HIV and Hepatitis C infection and coinfection by both. METHODS: A study was made of the database of positive serologies of the Laboratory Service of León General Hospital. Data were treated in accordance with the origin of the samples. To calculate rates, the municipal census of persons over 14 was used. For the prison population, the number of inmates on the last day of each year was considered. The period analysed was 1993-2004. The Chi-square test and Chi-square test for tendencies were used. RESULTS: The number of positive serologies for HCV, HIV and coinfection were 467, 112 and 78 in 1993; 217, 24 and 15 in 2002, and 294, 42 and 21 in 2004. According to the samples from the hospital, blood bank and health centres, the average annual rate per 100,000 inhabitants for the three-year periods 1993-95 and 2001-04 in men varied from 153.3 to 69.5 for HCV, from 26.2 to 10,0 for HIV and from 21.7 to 3.8 for coinfection. The figures for women were 56.6-37.7 for HCV, 9.2-2.3 for HIV and 6.3-0.4 for coinfection. In all cases, there was a significant downward trend (p<0.05). The positive serologies from the prison for the period 1993-2004 varied between 34.5% and 7.2% for HCV, 11.7%-1.1% for HIV and 9.55 and 1.0% for coinfection. Of those infected by HCV, 11.5% were HIV positive, and of those infected by HIV, 65.5% were also positive for HCV. CONCLUSIONS: A drop was observed in the number and rates of positive serological tests over the period studied.
Assuntos
Infecções por HIV/complicações , Infecções por HIV/epidemiologia , Hepatite C/complicações , Hepatite C/epidemiologia , Feminino , Humanos , Incidência , Masculino , Espanha/epidemiologiaRESUMO
Fundamento: Ante la escasez de registros poblacionales, elestudio de las serologías positivas detectadas en los servicios delaboratorio puede ser una aceptable aproximación para conocerlas tendencias de determinadas infecciones. El objetivo de estetrabajo es conocer la evolución de las infecciones por los virus dela inmunodeficiencia humana (VIH) y de la hepatitis C (VHC) asícomo de la coinfección (COIN) durante el período 1993-2004.Métodos: Se utilizó la base de datos de serologías positivasdel Servicio de Laboratorio del Hospital de León. La informaciónse estudió en función de la fuente origen de las muestras. Para elcálculo de las tasas se utilizó el padrón municipal de personasmayores de 14 años. Para la población reclusa el número de internadosel último día de cada año. Se analizó el periodo comprendidoentre 1993 y 2004. Se utilizaron las pruebas de Chi-cuadradoy de Chi-cuadrado para tendencias.Resultados: El número de serologías positivas para VHC,VIH y COIN fueron respectivamente 467, 112 y 78 en 1993; 217,24 y 15 para 2002 y 294, 42 y 21 en 2004. De acuerdo con lasmuestras procedentes del hospital, banco de sangre y ambulatorios,la tasa promedio anual por 100.000 habitantes para los períodos1993-95 y 2001-04 en hombres variaron de 153,3 a 69,5 paraVHC; de 26,2 a 10,0 para VIH y de 21,7 a 3,8 para COIN. En elcaso de las mujeres de 56,6 a 37,7 para VHC, de 9,2 a 2,3 paraVIH y de 6,3 a 0,4 para COIN. En todos los casos las tendenciasfueron significativamente descendentes (p<0,05). La razón deserologías positivas de las muestras provenientes de prisión bajóentre 1993-2004 del 34,5% al 7,2% para VHC; del 11,7% al 1,1%para VIH y del 9,5% al 1,0% para COIN. De los sujetos infectadospor VHC lo estaban también por VIH el 11,5% y el 65,6% yde los infectados por VIH lo estaban por VHC.Conclusiones: Se ha observado un descenso en el número ytasas de serologías positivas a lo largo del periodo de estudio(AU)
Background: As few population studies exist, the study ofpositive serological tests detected in laboratory services may bean acceptable approximation for the assessment of HIV andHepatitis C infection and coinfection by both.Methods: A study was made of the database of positiveserologies of the Laboratory Service of León General Hospital.Data were treated in accordance with the origin of the samples. Tocalculate rates, the municipal census of persons over 14 was used.For the prison population, the number of inmates on the last dayof each year was considered. The period analysed was 1993-2004.The Chi-square test and Chi-square test for tendencies were used.Results: The number of positive serologies for HCV, HIVand coinfection were 467, 112 and 78 in 1993; 217, 24 and 15 in2002, and 294, 42 and 21 in 2004. According to the samples fromthe hospital, blood bank and health centres, the average annualrate per 100,000 inhabitants for the three-year periods 1993-95and 2001-04 in men varied from 153.3 to 69.5 for HCV, from 26.2to 10,0 for HIV and from 21.7 to 3.8 for coinfection. The figuresfor women were 56.6-37.7 for HCV, 9.2-2.3 for HIV and 6.3-0.4for coinfection. In all cases, there was a significant downwardtrend (P<0.05). The positive serologies from the prison for theperiod 1993-2004 varied between 34.5% and 7.2% for HCV,11.7%-1.1% for HIV and 9.55 and 1.0% for coinfection. Of thoseinfected by HCV, 11.5% were HIV positive, and of those infectedby HIV, 65.5% were also positive for HCV.Conclusions:A drop was observed in the number and rates ofpositive serological tests over the period studied(AU)
