RESUMO
BACKGROUND: The lysine salt of bendazac is a non-steroidal anti-inflammatory agent, and it is marketed exclusively for the treatment of cataracts. We report two cases of possible hepatotoxicity due to the use of bendazac lysine. METHODS: Laboratory tests, serologic tests, abdominal sonography and scan were performed to study liver disease. RESULTS: Reversible increases of the hepatic enzymes were found in both cases. Anemia was also found in one of the cases (case 1). CONCLUSIONS: Abnormal liver test results could be related to a possible liver injury attributed to the use of bendazac lysine.
Assuntos
Anti-Inflamatórios não Esteroides/efeitos adversos , Catarata/tratamento farmacológico , Indazóis/efeitos adversos , Idoso , Idoso de 80 Anos ou mais , Anti-Inflamatórios não Esteroides/uso terapêutico , Relação Dose-Resposta a Droga , Esquema de Medicação , Feminino , Humanos , Indazóis/uso terapêutico , Testes de Função HepáticaRESUMO
Radiation enteritis is a common complication in patients receiving radiotherapy as a part of the treatment of abdominal malignancies. We report the case of a 57 year male patient with a renal carcinoma, who received radiotherapy and developed a double stenosis of the jejunum and the colon ten years later. He had to be treated surgically with resection of the affected segments. We would like to stress the possibility of this complication in patients who are to be treated with radiotherapy.