RESUMO
Roentgenographs from hands and feet have been made from 97 out of 162 patients suffering from a gangliopulmonary sarcoidosis. In 34 patients bone alterations have been stated. In cases of an advanced gangliopulmonary sarcoidosis the bone alterations were more frequent. In 23 cases the findings showed osteolytic characteristics. In 4 of the cases they consisted in circumscribed foci of condensation. In 7 cases osteolyses and condensations appeared in combination with one another. Up to now there are no data in literature about bone condensations in case of a sarcoidosis. Their classification into the aspect of this disease is recommended with due reserve.
Assuntos
Doenças Ósseas/etiologia , Sarcoidose/complicações , Doenças Ósseas/diagnóstico , Dedos , Pé , Humanos , Teste de Kveim , Linfonodos , Osteólise/etiologia , Sarcoidose/diagnósticoRESUMO
In order to be well determined the diagnosis of sarcoidosis needs multiple evidence of clinical, radiological, immunobiological and humoral order, and a histopathological confirmation too. Our casuistry covered 173 observations: Stage I with 94 (54.33%) cases, stage II with 68 (39.3%) cases, and stage III with 11 (6.4%) cases. In 136 patients one or several biopsies were performed with a histopathological result for sarcoidosis in 107 cases (61.8%). According to their character, biopsies could be divided into three groups: Group I comprised 39 biopsies of some easily accessible lesions (skin lesion, peripheral adenopathy, tonsils a.s.o.). 25 of them were concludent for sarcoidosis (64.1%). Group II was made up of 118 biopsies of some hardly accessible lesions (hepatic biopsy puncture, bronchoscopy, pre-scalene node biopsy). Of these biopsies, 22 pleaded for sarcoidosis (18.6%). In group III entered 67 deep biopsies (mediastinoscopy, hiloscopy, thoracotomy with pulmonary biopsy). All of them confirmed sarcoidosis. If to the concludent histopathological result for sarcoidosis (61.8%) we add the one given by the Kveim test (15.1%) (in cases without biopsy or with a non-concludent biopsy) the percentage of biopsy confirmation rises to 76.9%).
Assuntos
Pneumopatias/patologia , Sarcoidose/patologia , Biópsia por Agulha , Humanos , Mediastinoscopia , Métodos , Sarcoidose/classificação , Sarcoidose/diagnósticoRESUMO
The data on the epidemiologic situation of sarcoidosis from 24 countries of Europe have been reviewed. The new facts seem to demonstrate that the differences between the frequency of this disease in the north and south are not real. The actual situation is dependent on the general knowledge of this disease and on the extent and intensity of the active detection of its asymptomatic stage. A new prospective cooperative study of the yearly incidence of all forms of sarcoidosis in the total population of at least some European countries would be desirable.
