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1.
Front Psychol ; 14: 1244568, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38078214

RESUMO

Introduction: The recent COVID-19 pandemic has compelled various governments to trace all contacts of a confirmed case, as well as to identify the locations visited by infected individuals. This task, that requires the activation of our autobiographical memories, can make a difference in the spread of the contagion and was based primarily on telephone interviews with infected people. In this study, we examined whether participants were able to provide contact tracing information and whether their memories were influenced by salient events occurring during the initial phases of the pandemic. Methods: Participants were asked to fill in an online standardized form in which they recounted every day of the 2 weeks before, reporting as much information as possible. The time period selected included, among other things, the day on which the Italian government issued the decree initiating the COVID-19 lockdown. The task was completed twice, the first time relying solely on their memory, and the second time using external aids (diaries, mobile phones etc.). Reports were then coded using a scheme that segmented accounts into informational details, divided into two broad categories, internal and external. Results: Our findings showed that (i) the use of external aids was effective only when participants had to recall the day furthest away or if to-be-recalled events have low distinctiveness, and (ii) memories of internal details were recalled better than memories of external details. Participants were overall accurate and reported a large amount of information about people and places. However, because of the connection with key pandemic-related events, the effect was somewhat stronger on specific days (e.g., the day in which the lockdown was announced). Discussion: The results of this work could provide a useful tool for improving the design of contact tracing procedures in the event of an unwanted future public health crisis caused by a highly infectious agent.

2.
Curr Psychol ; : 1-13, 2023 May 24.
Artigo em Inglês | MEDLINE | ID: mdl-37359627

RESUMO

Previous studies demonstrated the positive and negative effects of collaboration on memory (both veridical and false recall) and suggestibility in face-to-face contexts. However, it remains unclear whether the same results can be observed in a virtual context. To clarify this issue, the present study examined the performance of 10 nominal triads and 10 collaborative triads in a fully online setting. Participants interacted live, in videoconference and were tested with the Gudjonsson Suggestibility Scale (GSS) and the Deese/Roediger-McDermott (DRM) task. For the GSS, the results replicated the in-person pattern of results, with collaborative triads showing the standard inhibition effect in the immediate and delayed (after 24 h) recall tasks; in addition, collaborative triads were less suggestible than nominal triads. For the DRM, we likewise found that collaboration decreased the recall and recognition of both studied items (the standard inhibitory effect) and critical lures (the error-pruning effect). We therefore conclude that remembering in a virtual context exhibits the same general properties as its in-person counterpart, at least when using a videoconference setting.

3.
Acta Psychol (Amst) ; 237: 103945, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37210865

RESUMO

In previous studies, anti-vaccination attitudes have been attributed either to far-right voters or to both far-left and far-right voters. The present study investigated the associations of political orientation with vaccine hesitancy and intention to be vaccinated against COVID-19, and the potential mediating roles of trust in science and belief in misinformation. A total of 750 Italian respondents completed an online questionnaire in the period between the second and the third wave of COVID-19 (from 9th March to 9th May 2021). The results showed that political orientation had both direct and indirect associations with vaccine hesitancy and vaccine intention, mediated by trust in science and belief in misinformation. Specifically, right-wing adherents were less trustful of scientists and believed in COVID-19-related misinformation more than left-wing adherents, and these two factors accounted for their higher vaccine hesitancy and reduced willingness to receive an anti-COVID-19 vaccination. Our findings are in line with the predictions of the mindsponge theory and suggest that communicative campaigns aimed at improving the rates of vaccine acceptance in right-wing adherents should be specifically focused on enhancing trust in science and reducing belief in misinformation.


Assuntos
COVID-19 , Intenção , Humanos , Confiança , Hesitação Vacinal , COVID-19/prevenção & controle , Comunicação
4.
Front Neurosci ; 17: 1112805, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37034170

RESUMO

Introduction: Remembering where negative events occur has undeniable adaptive value, however, how these memories are formed remains elusive. We investigated the role of working memory subcomponents in binding emotional and visuo-spatial information using an emotional version of the object relocation task (EORT). Methods: After displaying black rectangles simultaneously, emotional pictures (from the International Affective Pictures System) appeared sequentially over each rectangle. Participants repositioned the rectangles as accurately as possible after all stimuli had disappeared. During the EORT encoding phase, a verbal trail task was administered concurrently to selectively interfere with the central executive (CE). The immediate post-encoding administration of an object feature-report task was used to interfere with the episodic buffer (EB). Results: Only the EB-interfering task prevented the emotion-enhancing effect of negative pictures. The latter effect was not observed with a concurrent executive task. Discussion: Overall, our findings suggest that pre-attentive automatic processes are primarily involved in binding emotional and visuo-spatial information in the EB.

5.
J Pers Med ; 12(1)2022 Jan 14.
Artigo em Inglês | MEDLINE | ID: mdl-35055426

RESUMO

COVID-19 vaccines are the most promising means of limiting the pandemic. The present study aims at determining the roles of several psychological variables in predicting vaccination intention in Italy. An online questionnaire was disseminated between 9 March and 9 May 2021. The sample included 971 participants. Results showed that most of the participants were willing to vaccinate. Acceptance rates were correlated with age, marital status, and area of residence. Intention to be vaccinated was positively correlated with perceived risk, pro-sociality, fear of COVID-19, use of preventive behaviors, and trust in government, in science, and in medical professionals. Intention to be vaccinated was negatively associated with belief in misinformation. The degree of acceptance is likely to be a result of the campaign tailored to address people's negative attitudes towards vaccines. Trust in government and trust in science were among the strongest psychological predictors of vaccination intention. Fear of COVID-19, but not perceived risk, was associated with increased vaccine uptake, suggesting that the affective component of risk perception was more important than the cognitive component in predicting participants' behaviors. Belief in misinformation was associated with reduced vaccination intention. Future studies will take into consideration these variables, to better understand the multifaceted process underlying vaccination intention.

6.
J Exp Psychol Learn Mem Cogn ; 48(8): 1083-1097, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-33818117

RESUMO

In the Attentional Boost Effect (ABE), words or images encoded with to-be-detected target squares are later recognized better than words or images encoded with to-be-ignored distractor squares. The present study sought to determine whether the ABE enhanced the encoding of the item-specific and relational properties of the studied words by using the multiple recall paradigm. Previous evidence indicates that manipulations fostering item-specific encoding increased the number of item gains, whereas manipulations fostering relational encoding decreased item losses. Across three experiments, participants were presented with lists of semantically related or unrelated words paired with target (red) or distractor (green) squares, under the instructions to remember all the words and press the spacebar when the square was red. Immediately after the study phase, they were involved in four consecutive recall attempts. In all cases, the classical ABE was replicated, in that participants recalled more target- than distractor-paired words. Most importantly, the analyses converged in showing that item gains were significantly greater for target- than for distractor-paired words when participants studied lists of related words (but not when they studied unrelated lists); in contrast, item losses did not differ between the two types of words, irrespective of the nature of the studied list. Taken together, these data suggest that the ABE enhanced the encoding of item-specific information but had no effect on the encoding of relational information. (PsycInfo Database Record (c) 2022 APA, all rights reserved).


Assuntos
Atenção , Rememoração Mental , Humanos
7.
J Pers Med ; 11(3)2021 Mar 06.
Artigo em Inglês | MEDLINE | ID: mdl-33800780

RESUMO

In the Attentional Boost Effect (ABE), stimuli encoded with to-be-responded targets are later recognized more accurately than stimuli encoded with to-be-ignored distractors. While this effect is robust in young adults, evidence regarding healthy older adults and clinical populations is sparse. The present study investigated whether a significant ABE is present in bipolar patients (BP), who, even in the euthymic phase, suffer from attentional deficits, and whether the effect is modulated by age. Young and adult euthymic BP and healthy controls (HC) presented with a sequence of pictures paired with target or distractor squares were asked to pay attention to the pictures and press the spacebar when a target square appeared. After a 15-min interval, their memory of the pictures was tested in a recognition task. The performance in the detection task was lower in BP than in HC, in both age groups. More importantly, neither young nor adult BP exhibited a significant ABE; for HC, a robust ABE was only found in young participants. The results suggest that the increase in the attentional demands of the detection task in BP and in adult HC draws resources away from the encoding of target-associated stimuli, resulting in elimination of the ABE. Clinical implications are discussed.

8.
J Pers Med ; 11(4)2021 Mar 26.
Artigo em Inglês | MEDLINE | ID: mdl-33810436

RESUMO

Intrusive memories are a common feature of many psychopathologies, and suppression-induced forgetting of unwanted memories appears as a critical ability to preserve mental health. In recent years, biological and cognitive studies converged in revealing that forgetting is due to active processes. Recent neurobiological studies provide evidence on the active role of main neurotransmitter systems in forgetting, suggesting that the brain actively works to suppress retrieval of unwanted memories. On the cognitive side, there is evidence that voluntary and involuntary processes (here termed "intentional" and "incidental" forgetting, respectively) contribute to active forgetting. In intentional forgetting, an inhibitory control mechanism suppresses awareness of unwanted memories at encoding or retrieval. In incidental forgetting, retrieval practice of some memories involuntarily suppresses the retrieval of other related memories. In this review we describe recent findings on deficits in active forgetting observed in psychopathologies, like post-traumatic stress disorder, depression, schizophrenia, and obsessive-compulsive disorder. Moreover, we report studies in which the role of neurotransmitter systems, known to be involved in the pathogenesis of mental disorders, has been investigated in active forgetting paradigms. The possibility that biological and cognitive mechanisms of active forgetting could be considered as hallmarks of the early onset of psychopathologies is also discussed.

9.
Cortex ; 134: 253-264, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33307270

RESUMO

Humans are prone to mentally organise the ascending series of integers according to reading habits so that in western cultures small numbers are positioned to the left of larger ones on a mental number line. Despite 140 years since seminal observations by Sir Francis Galton (Galton, 1880a, b), the functional mechanisms that give rise to directional Space-Number Associations (SNAs) remain elusive. Here, we contrasted three different experimental conditions, each including a different version of a Go/No-Go task with intermixed numerical and arrow-targets (Shaki and Fischer, 2018; Pinto et al., 2019a). We show that directional SNAs are not "all or none" phenomena. We demonstrate that SNAs get progressively less noisy and more stable the more contrasting small/large magnitude-codes and contrasting left/right spatial-codes are explicitly and fully combined in the task set. The analyses of the time-course of space-number congruency effects showed that both the absence and presence of the SNA were independent of the speed of reaction times. In agreement with our original proposal (Aiello et al., 2012), these findings show that conceptualising the ascending series of integers in spatial terms depends on the use of spatial codes in the numerical task at hand rather than on the presence of an inherent spatial dimension in the semantic representation of numbers. This evidence suggests that directional SNAs, like the SNARC effect, are secondary to the primary transfer of spatial response codes to number stimuli, rather than deriving from a primary congruency or incongruence between independent spatial-response and spatial-number codes.


Assuntos
Idioma , Percepção Espacial , Humanos , Matemática , Tempo de Reação , Semântica
10.
Memory ; 28(7): 926-937, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32723155

RESUMO

In the Attentional Boost Effect (ABE), images or words encoded with unrelated to-be-responded targets are later remembered better than images or words encoded with to-be-ignored distractors. In the realm of short-term memory, the ABE has been previously shown to enhance the short-term recognition of single-feature stimuli. The present study replicated this finding and extended it to a condition requiring the encoding and retention of colour-shape associations. Across four experiments, participants studied arrays of four coloured squares (the colour-only condition), four gray shapes (the shape-only condition) or four coloured shapes (the binding condition), paired with either a target letter (to which participants had to respond by pressing the spacebar) or a distractor letter (for which no response was required). After a short delay, they were presented with a probe array and asked to decide whether it matched or not the encoded array. Results showed that, in all conditions, the recognition of target-paired arrays was significantly better than the recognition of distractor-paired arrays. These findings suggest that the ABE can enhance feature binding.


Assuntos
Atenção , Memória de Curto Prazo , Reconhecimento Psicológico , Humanos , Rememoração Mental
11.
Exp Brain Res ; 238(9): 2031-2040, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32617884

RESUMO

Picking-up and exploiting spatial and temporal regularities in the occurrence of sensory events is important for goal-directed behaviour. According to the "Predictive Coding Hypothesis" (Friston Philosophical Trans R Soc B 360(1456):815-836, 2005), these regularities are used to generate top-down predictions that are constantly compared with actual sensory events. In a previous study with the Attentional Blink (AB) paradigm, we showed that the temporal and probabilistic uncertainty of T2s that are presented outside the Attentional Blink period, i.e. at least 400 ms after T1, improves the conscious report of T2 that are presented inside the AB. The study of ERP correlated showed that this improvement was associated with a prolonged storage of pre-conscious T2 traces in extra-striate areas (Lasaponara et al. Cortex 71:15-33, 2015). Here, we tested whether variations in the probabilistic cueing of the position of a primary T1 visual target in a 4 × 4 letter array, modulate the retention of memory traces evoked by secondary letter targets (T2) that were presented in other positions of the array. Most important, in each trial, the identity of T2 was specified to participants upon disappearance of the array. We show that high probabilistic cueing facilitates T1 detection and improves the corresponding sensitivity index (d'). In contrast, retention and conscious report of secondary targets (T2) improves when the probabilistic cueing of T1 position is poor. These results suggest that uncertainty in the upcoming position of primary targets boosts the strength of memory traces evoked by secondary targets and improves the possibility that traces of secondary targets gain full access to conscious processing.


Assuntos
Intermitência na Atenção Visual , Córtex Visual , Estado de Consciência , Sinais (Psicologia) , Humanos , Incerteza
12.
J Cogn Neurosci ; 32(6): 1046-1060, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-31967519

RESUMO

Orienting of attention produces a "sensory gain" in the processing of visual targets at attended locations and an increase in the amplitude of target-related P1 and N1 ERPs. P1 marks gain reduction at unattended locations; N1 marks gain enhancement at attended ones. Lateral targets that are preceded by valid cues also evoke a larger P1 over the hemisphere contralateral to the no-target side, which reflects inhibition of this side of space [Slagter, H. A., Prinssen, S., Reteig, L. C., & Mazaheri, A. Facilitation and inhibition in attention: Functional dissociation of pre-stimulus alpha activity, P1, and N1 components. Neuroimage, 125, 25-35, 2016]. To clarify the relationships among cue predictiveness, sensory gain, and the inhibitory P1 response, we compared cue- and target-related ERPs among valid, neutral, and invalid trials with predictive (80% valid/20% invalid) or nonpredictive (50% valid/50% invalid) directional cues. Preparatory facilitation over the visual cortex contralateral to the cued side of space (lateral directing attention positivity component) was reduced during nonpredictive cueing. With predictive cues, the target-related inhibitory P1 was larger over the hemisphere contralateral to the no-target side not only in response to valid but also in response to neutral and invalid targets: This result highlights a default inhibitory hemispheric asymmetry that is independent from cued orienting of attention. With nonpredictive cues, valid targets reduced the amplitude of the inhibitory P1 over the hemisphere contralateral to the no-target side whereas invalid targets enhanced the amplitude of the same inhibitory component. Enhanced inhibition was matched with speeded reorienting to invalid targets and drop in attentional costs. These findings show that reorienting of attention is modulated by the combination of cue-related facilitatory and target-related inhibitory activity.


Assuntos
Atenção/fisiologia , Sinais (Psicologia) , Potenciais Evocados/fisiologia , Lateralidade Funcional/fisiologia , Inibição Neural/fisiologia , Orientação/fisiologia , Desempenho Psicomotor/fisiologia , Percepção Espacial/fisiologia , Percepção Visual/fisiologia , Adulto , Eletroencefalografia , Feminino , Humanos , Masculino , Adulto Jovem
13.
Acta Psychol (Amst) ; 203: 102986, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31887634

RESUMO

Previous studies showed that collaborative remembering can reduce false memories through a process of mutual error checking, although conclusions were limited by the nature of the memory tasks (very few errors). The present experiments extend these findings to eyewitness memory by using a paradigm designed to increase the frequency of memory errors. Collaborative and nominal pairs viewed a video-clip illustrating a bank robbery, provided an immediate free recall, were forced to confabulate answers to false-event questions, and, after a short- (1 h: Experiment 1) or a long-term delay (1 week: Experiment 2), were administered a yes/no recognition task in which the misleading statements either matched the questions presented in the confabulation phase (answered questions) or not (control questions). Collaborative pairs recalled fewer correct details in the immediate free recall task, replicating the negative effects of collaborative inhibition. Most importantly, in the final recognition test, collaborative pairs were less likely to provide false assents to misleading statements, regardless of whether they had provided a response to the related false-event questions 1 h or 1 week earlier. Our results suggest that collaboration can increase the eyewitnesses' tendency to check the accuracy of others' responses and reject false memories through discussion.


Assuntos
Comunicação , Comportamento Cooperativo , Memória de Curto Prazo/fisiologia , Rememoração Mental/fisiologia , Adulto , Feminino , Humanos , Masculino , Distribuição Aleatória , Reconhecimento Psicológico/fisiologia , Comportamento Social , Fatores de Tempo , Adulto Jovem
14.
Psychol Res ; 84(7): 2065-2077, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31183548

RESUMO

Previous studies have shown that, under specific conditions, arrays that have been pointed at encoding are recognized better than passively viewed ones. According to one interpretation, the superior recognition of pointed-to arrays can be explained by the motor inhibition of passively viewed arrays. The present study sought to determine whether a similar motor inhibition can be induced also when the participants observed a co-actor perform the pointing movements. Participants were presented with two spatial arrays, one of which was encoded via observation only (the no-move array), while the other was encoded with pointing movements (the move array); movements were performed either by the participant or by the experimenter. Experiment 1 replicated the advantage of self-pointed arrays over passively viewed arrays. Experiment 2 showed that, when participants passively observed the pointing movements performed by the experimenter, move arrays were recognized no better than no-move arrays. Finally, Experiment 3 demonstrated that, in a joint-action condition in which participants alternated with the experimenter in making pointing movements, the advantage of experimenter-pointed arrays over passively viewed arrays was significant and similar in size to the advantage produced by self-performed movements. Importantly, a series of cross-experiment comparisons indicated that the higher recognition of both self- and experimenter-pointed arrays in Experiment 3 could be explained by the motor inhibition of no-move arrays. We propose that, in a joint condition, the pointing movements performed by the experimenter were represented in the same functional way as self-performed movements and that this produced the motor inhibition of passively viewed arrays.


Assuntos
Inibição Psicológica , Memória de Curto Prazo/fisiologia , Movimento/fisiologia , Desempenho Psicomotor/fisiologia , Memória Espacial/fisiologia , Adulto , Feminino , Humanos , Itália , Masculino , Estudantes , Universidades , Adulto Jovem
15.
Front Psychol ; 10: 2587, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31803120

RESUMO

Remembering places in which emotional events occur is essential for individual's survival. However, the mechanisms through which emotions modulate information processing in working memory, especially in the visuo-spatial domain, is little understood and controversial. The present research was aimed at investigating the effect of incidentally learned emotional stimuli on visuo-spatial working memory (VSWM) performance by using a modified version of the object-location task. Eight black rectangles appeared simultaneously on a computer screen; this was immediately followed by the sequential presentation of eight pictures (selected from IAPS) superimposed onto each rectangle. Pictures were selected considering the two main dimensions of emotions: valence and arousal. Immediately after presentation, participants had to relocate the rectangles in the original position as accurately as possible. In the first experiment arousal and valence were manipulated either as between-subject (Experiment 1A) or as within-subject factors (Experiment 1B and 1C). Results showed that negative pictures enhanced memory for object location only when they were presented with neutral ones within the same encoding trial. This enhancing effect of emotion on memory for object location was replicated also with positive pictures. In Experiment 2 the arousal level of negative pictures was manipulated between-subjects (high vs. low) while maintaining valence as a within-subject factor (negative vs. neutral). Objects associated with negative pictures were better relocated, independently of arousal. In Experiment 3 the role of emotional valence was further ascertained by manipulating valence as a within-subject factor (neutral vs. negative in Experiment 3A; neutral vs. positive in Experiment 3B) and maintaining similar levels of arousal among pictures. A significant effect of valence on memory for location was observed in both experiments. Finally, in Experiment 4, when positive and negative pictures were encoded in the same trial, no significant effect of valence on memory for object location was observed. Taken together results suggest that emotions enhance spatial memory performance when neutral and emotional stimuli compete with one another for access into the working memory system. In this competitive mechanism, an interplay between valence and arousal seems to be at work.

16.
Exp Brain Res ; 237(10): 2633-2643, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31384968

RESUMO

The Attentional-SNARC effect (Att-SNARC) originally described by Fischer et al. (Nat Neurosci 6(6):555, 2003), consists of faster RTs to visual targets in the left side of space when these are preceded by small-magnitude Arabic cues at central fixation and by faster RTs to targets in the right side of space when these are preceded by large-magnitude cues. Verifying the consistency and reliability of this effect is important, because the effect would suggest an inherent association between the representation of space and that of number magnitude, while a number of recent studies provided no positive evidence in favour of the Att-SNARC and the inherency of this association (van Dijck et al. in Q J Exp Psychol 67(8):1500-1513, 2014; Zanolie and Pecher in Front Psychol 5:987, 2014; Fattorini et al. in Cortex 73:298-316, 2015; Pinto et al. in Cortex, DOI:10.1016/j.cortex.2017.12.015, 2018). Here, we re-analysed Att-SNARC data that we have collected in 174 participants over different studies run in our laboratory. Most important, in a subsample of 79 participants, we also verified whether the strength and reliability of the Att-SNARC is eventually linked inter-individual variations in finger counting style, imagery vividness, and verbal/visual learning style. We found no evidence for the Att-SNARC effect or for the influence of finger counting style, imagery vividness, and learning style on its direction or consistency. These results confirm no inherent link between orienting of spatial attention and representation of number magnitudes. We propose that this link is rather determined by the joint use of spatial and number magnitude or parity codes in the performance of the numerical task at hand.


Assuntos
Atenção/fisiologia , Cognição/fisiologia , Desempenho Psicomotor/fisiologia , Percepção Espacial/fisiologia , Adulto , Feminino , Lateralidade Funcional/fisiologia , Humanos , Imagens, Psicoterapia/métodos , Masculino , Matemática , Reprodutibilidade dos Testes , Adulto Jovem
17.
Acta Psychol (Amst) ; 198: 102887, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31351325

RESUMO

The SNARC effect consists of faster reaction times to small numerical magnitudes when manual responses are delivered in the left-side of space and to large magnitudes when responses are delivered in the right-side. This spatial compatibility effect points at the interaction between the representations of space and that of numbers. Several studies have highlighted that an important determinant for the production of the SNARC is the use of contrasting left/right spatial codes in the selection of motor responses. In these studies, one spatial code for response selection, e.g. "left", is usually associated with one number feature, e.g. "lower than 5", while the contrasting spatial code, e.g. "right", is associated with the contrasting number feature, e.g. "higher than 5". Using a task with intermixed number and letter targets, here we show that significant and reliable SNARC effects are also produced when: a) one spatial response is associated with the intra-categorical discrimination of a number feature (i.e. magnitude or parity) and the contrasting response with the simple detection of letter targets; b) or when one spatial response is associated with the intra-categorical discrimination of the position of a letter in the alphabet (i.e. before or after "m") and the contrasting spatial response with the simple detection of numerical targets (Experiments 1 and 2). In contrast, no reliable SNARC is found when no intra-categorical number or letter discrimination is required and contrasting left/right spatial response codes are simply associated with the discrimination between numbers and letters, e.g. "push left if the target is a number/push right if it is a letter" (Experiment 3). In a final control test (Experiment 4), we found no SNARC when the magnitude or parity classification of Arabic digits presented at central fixation was made unimanually with a left side or a right side-key and no left/right contrast was present in response selection. These results show that the use of contrasting left/right spatial response codes elicits reliable SNARC effects independently of their assignment to contrasting number features and confirm the important role played by the use of spatial codes in the genesis of the number-space interaction.


Assuntos
Cognição/fisiologia , Conceitos Matemáticos , Tempo de Reação/fisiologia , Percepção Espacial/fisiologia , Adulto , Feminino , Humanos , Masculino , Adulto Jovem
18.
Artigo em Inglês | MEDLINE | ID: mdl-30953677

RESUMO

Disturbances in fear-evoked signal transduction in the hippocampus (HP), the nuclei of the amygdala (AMY), and the prefrontal cortex (PFC) underlie anxiety-related disorders. However, the molecular mechanisms underlying these effects remain elusive. Heterotrimeric G proteins (GPs) are divided into the following four families based on the intracellular activity of their alpha subunit (Gα): Gα(s) proteins stimulate cyclic AMP (cAMP) generation, Gα(i/o) proteins inhibit the cAMP pathway, Gα(q/11) proteins increase the intracellular Ca++ concentration and the inositol trisphosphate level, and Gα(12/13) proteins activate monomeric GP-Rho. In the present study, we assessed the effects of a fear memory procedure on the mRNA expression of the Gα subunits of all four GP families in the HP, AMY and PFC. C57BL/6 J mice were subjected to a fear conditioning (FC) procedure followed by a contextual or cued fear memory test (CTX-R and CS-R, respectively). Morphine (MOR, 1 mg/kg/ip) was injected immediately after FC to prevent the fear consolidation process. Real-time quantitative PCR was used to measure the mRNA expression levels of Gα subunits at 1 h after FC, 24 h after FC, and 1 h after the CTX-R or CS-R. In the HP, the mRNA levels of Gα(s), Gα(12) and Gα(11) were higher at 1 h after training. Gα(s) levels were slightly lower when consolidation was stabilized and after the CS-R. The mRNA levels of Gα(12) were increased at 1 h after FC, returned to control levels at 24 h after FC and increased again with the CTX-R. The increase in the Gα(11) level persisted at 24 h after FC and after CTX-R. In the AMY, no specific changes were induced by FC. In the PFC, CTX-R was accompanied by a decrease in Gα(i/o) mRNA levels; however, only Gα(i2) downregulation was prevented by MOR treatment. Hence, the FC-evoked changes in Gα mRNA expression were observed mainly in the HP and connected primarily to contextual learning. These results suggest that the activation of signaling pathways by Gα(s) and Gα(12) is required to begin the fear memory consolidation process in the HP, while signal transduction via Gα(11) is implicated in the maintenance of fear consolidation. In the PFC, the downregulation of Gα(i2) appears to be related to the contextual learning of fear.


Assuntos
Encéfalo/metabolismo , Medo , Proteínas de Ligação ao GTP/metabolismo , Memória/efeitos dos fármacos , Morfina/farmacologia , Animais , Encéfalo/efeitos dos fármacos , Condicionamento Clássico/efeitos dos fármacos , Sinais (Psicologia) , Medo/efeitos dos fármacos , Hipocampo/efeitos dos fármacos , Hipocampo/metabolismo , Masculino , Camundongos , Camundongos Endogâmicos C57BL , RNA Mensageiro/metabolismo
19.
Memory ; 27(5): 603-611, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30384799

RESUMO

Collaboration during the retrieval phase can have both negative and positive effects (referred to as collaborative inhibition and error pruning, respectively) on emotional and eyewitness memory. To further elucidate these issues, the present experiment used the Gudjonsson Suggestibility Scale to investigate the question of whether collaborative remembering reduced post-event suggestibility. Collaborative and nominal pairs listened to the GSS2, provided immediate and delayed (after 30 min) free recalls, and answered a series of leading questions before or after receiving a negative feedback about their performance. We found no evidence of collaborative inhibition in the immediate and delayed free recall tasks. Importantly, however, collaborative pairs produced less confabulated elements in the free recall tasks, were considerably less prone to give in to leading questions (both before and after receiving the negative feedback), and exhibited lower levels of Total Suggestibility, compared to both nominal and individual dyads. Taken together, these results support the conclusion that collaboration can have a beneficial influence on eyewitnesses' accuracy, by strengthening their resistance to post-event suggestibility.


Assuntos
Comportamento Cooperativo , Rememoração Mental , Sugestão , Retroalimentação Psicológica , Feminino , Humanos , Inibição Psicológica , Masculino , Fatores de Tempo , Adulto Jovem
20.
Memory ; 26(1): 42-52, 2018 01.
Artigo em Inglês | MEDLINE | ID: mdl-28436271

RESUMO

The present study examined predictions of the early-phase-elevated-attention hypothesis of the attentional boost effect (ABE), which suggests that transient increases in attention at encoding, as instantiated in the ABE paradigm, should enhance the recognition of neutral and positive items (whose encoding is mostly based on controlled processes), while having small or null effects on the recognition of negative items (whose encoding is primarily based on automatic processes). Participants were presented a sequence of negative, neutral and positive stimuli (pictures in Experiment 1, words in Experiment 2) associated to target (red) squares, distractor (green) squares or no squares (baseline condition). They were told to attend to the pictures/words and simultaneously press the spacebar of the computer when a red square appeared. In a later recognition task, stimuli associated to target squares were recognised better than stimuli associated to distractor squares, replicating the standard ABE. More importantly, we also found that: (a) the memory enhancement following target detection occurred with all types of stimuli (neutral, negative and positive) and (b) the advantage of negative stimuli over neutral stimuli was intact in the DA condition. These findings suggest that the encoding of negative stimuli depends on both controlled (attention-dependent) and automatic (attention-independent) processes.


Assuntos
Atenção , Emoções , Memória , Reconhecimento Psicológico , Adulto , Viés de Atenção , Feminino , Humanos , Masculino , Estimulação Luminosa , Adulto Jovem
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