[Morbidity reduction in preterm newborns fed with milk of their own mothers]. / Disminución de la morbilidad en neonatos pretérmino alimentados con leche de su propia madre.

In order to study the effect of feeding on the morbidity, 118 premature newborn, were followed on successive basis; 59 fed with infant term formula (F) and 59 fed with own mother's milk (LH). The patients were classified in 3 groups according to birth weight: I, < 999 g (n = 4/4); II, 1000-1499 g (n = 37/37) and III, 1500-1999 g (n = 18/18), each group F and LH having equal numbers. Growth, morbidity and clinical management were recorded. Necrotizing enterocolitis (P < 0.001), urinary tract infection (P < 0.01) and infectious diarrhea (P < 0.01) were less frequent in LH infants and as a consequence these infants needed less antimicrobial therapy (P < 0.001), nevertheless the human milk contained flora bacteria. The LH infants of group II need fewer red cell transfusions (P < 0.001) and each group was similar and only the babies < 999 g had increments of approximately 15 g/kg/day. This study highlights the importance of feeding the premature infant with own mother's milk; however, the infant growth increments were less than the expected suggesting that human milk must be fortified with proteins and minerals, considering the mothers as a true human milk bank.

Miastenia grave neonatal. Informe de un caso. / Neonatal myasthenia gravis.Report of a case

Se presenta la comunicacion de un caso de miastenia grave neonatal manejado en el Departamento de Perinatologia del Hospital de Gineco-Obstetricia Num. 2 del Centro Medico Nacional. Se hace la revision de las formas clinicas de miastenia grave, la fisiopatologia y los datos inmunologicos distintos. Se analiza la frecuencia de aparicion de los signos y sintomas clinicos las posibles complicaciones a corto y largo plazo en caso de no diagnosticarse el cuadro o no instituir la terapeutica indicada. Finalmente se revisa la literatura mundial en relacion con la patologia estudiada

[Alpha-1-antitrypsin in the newborn with idiopathic respiratory distress syndrome]. / Alfa-1-antitripsina en neonatos con síndrome de insuficiencia respiratoria idiopática.

The study included 50 newborns with (RDS) and 41 controls in relation with the plasma concentration of alpha-antitrypsin (a-l-AT) and of proteins. The blood samples were taken at 24, 72 and 120 postnatal hours. At 24 hours, in infants with IRDS 187.5 +/- 9 mg/dl of a-l-AT were shown and 4.15 +/- 0.09 g. % of total proteins, which compared with concentrations of a-l-AT and total proteins in controls of the same age, turned out significantly lower. The a-l-AT and total proteins suffered increment in their concentrations at 72 hours of life in relation to control cases in whom there was no modifications in the course of postnatal age. Among other factors, a drop in total protein was considered related to the drop in globulin fraction. The usefulness of quantification of a-l-AT for the diagnosis of IRDS, is pointed out at the end.