Mesenteric Mixed Type of Castleman Disease: A Report of a Rare Case.

Castleman disease is a rare type of lymph node hyperplasia primarily affecting the mediastinum, with mesenteric localization being extremely uncommon. It is classified into solitary and multicentric forms. In this case report, we present the case of a 46-year-old female patient in whom an incidental mesenteric mass was discovered during the workup for a ventral hernia. The mass was completely excised, and the histopathological examination confirmed the diagnosis of mixed-type Castleman disease. Surgery is the treatment of choice for localized forms of this condition, and histological examination is crucial in confirming the diagnosis.

A Solitary Abscessed Hydatid Cyst of the Buttock: A Rare Case.

The hydatid cyst is a cosmopolitan parasitic infection caused by tapeworms of the genus Echinococcus and is a major public health problem in developing countries. Solitary hydatid cysts located in the buttocks are very rare, and the unusual location of the cyst can aid in the differential diagnosis of subcutaneous masses in this area, particularly in endemic areas. In this report, we present the case of a 39-year-old man who was admitted to the emergency department with a painful, abscessed cyst in the buttock region. The cyst was completely excised, and histopathological examination confirmed the diagnosis of a hydatid cyst. Further investigations did not reveal any other locations. Although the buttock region is an extremely rare site of infection for a hydatid cyst, it should be considered in cystic lesions, especially in endemic areas.

Neuroendocrine carcinoma of the gallbladder concomitant with adenocarcinoma of the sigmoid colon: A rare case report.

INTRODUCTION AND IMPORTANCE: Neuroendocrine carcinoma of the gallbladder is rare and aggressive, its diagnosis is based on pathologic and immunohistochemical examination, currently there is no standard treatment for this tumor. Its concomitant occurrence with adenocarcinoma of the sigmoid colon is exceptional. CASE PRESENTATION: This case report describes a rare case of neuroendocrine carcinoma of the gallbladder that occurred concomitantly with sigmoid colon adenocarcinoma. The diagnosis of neuroendocrine carcinoma was established postoperatively by pathological and immunohistochemical examination. The biopsy of the colonic process confirmed the preoperative diagnosis. A laparotomy found a vesicular fundus process, peri-hilar adenopathy, metastasis of the liver segment V, and a sigmoid colon process. The patient underwent a cholecystectomy extended to segments IVb and V, with lymph node dissection and sigmoid colectomy. The postoperative follow-up was uneventful, and the length of hospitalization was seven days. The patient is currently undergoing adjuvant chemotherapy. DISCUSSION: Neuroendocrine carcinoma of the gallbladder is extremely rare, with few case reports, its occurrence concomitantly with adenocarcinoma of the sigmoid colon is exceptional. Histology and immunohistochemistry confirm the diagnosis, surgery is essential in the management of patients affected by this tumor. The presence of synchronous metastases causes doubt about their primitive, hence the primordial place of surgery and histological examination to adopt adequate management of the patients. CONCLUSION: We underline the rarity of this neuroendocrine tumor and the importance of histology and surgery in its management.

Isolated Splenic Tuberculosis in an Immunocompetent Patient: A Rare Case.

Tuberculosis (TB) is one of the top 10 causes of death worldwide and the leading cause of death from a single infectious agent. Despite early diagnosis and improvements in medical science, the incidence of the disease is still a major public health problem in developing countries. Splenic tuberculosis is quite rare and occurs mostly as a part of miliary tuberculosis in individuals with immunosuppression. Isolated splenic tuberculosis is extremely rare in immunocompetent patients. We report a case of an immunocompetent man with isolated splenic tuberculosis.