[The association of autoimmune thyroiditis with HLA-B8 in the Georgian population].

The study of distribution of HLA antigens among Georgian population in case of autoimmune thyreoiditis revealed a statistically significant association of HLA-B8 antigen with autoimmune thyreoiditis. For statistical analysis we used following criterion: relative risk, attributive risk, preventive fraction, correlation coefficient and immunogenetic correction (P). Without compatibility to these criteria, there were no associations of the HLA antigens with the diseases. Although 8 of the antigens gave relative risk more than one, but only HLA B8 gave real association with autoimmune thyreoiditis. Typing of HLA antigens of class I and class II loci was done by classic microlymphocytotoxic test. The test performed on the lymphocytes from patients with autoimmune thyreoiditis. The character of association of HLA antigens among Georgian population with Hashimoto disease differs in character from other populations that evidently can be explained by the distributional character of HLA antigens among normal Georgian population.

[Solid-phase method in determination of blood groups and rhesus factor]. / Tverdofaznyi metod opredeleniia grupp krovi i rezus-faktora.

A new method for identification of blood group and Rh factor on polystyrene plates has been developed. For blood group identification the test serum is fixed with fruglumines, for Rh factor identification antiglobulin serum is fixed with 10% gamma-globulin. Blood group and Rh factor were identified in 38 donors; the data indicate a high activity and reliability of typing test plates.

[Preparation of universal anti-rhesus sera using soluble synthetic group A and B substances]. / Poluchenie universal'nykh syvorotok antirezus s pomoshch'iu rastvorimykh sinteticheskikh gruppovykh veshchestv A i B.

Isohemagglutinins alpha and beta were neutralized by soluble synthetic group A and B substances in group ++anti-rhesus sera. The investigations conducted have shown that water-soluble polymers A and B are efficient agents for the preparation of universal ++anti-rhesus sera. The neutralizing properties of synthetic and natural group A and B substances were comparatively studied.