Assuntos
Intenção , Projetos de Pesquisa , Humanos , Análise de Intenção de Tratamento , Viés , Resultado do TratamentoAssuntos
Intenção , Projetos de Pesquisa , Humanos , Análise de Intenção de Tratamento , Viés , Resultado do TratamentoRESUMO
We present the design process and implementation of fully open-source, ultra-low noise programmable current source systems in two configurations. Although originally designed as coil drivers for Optically Pumped Magnetometers (OPMs), the device specifications make them potentially useful in a range of applications. The devices feature a bi-directional current range of ±10 and ±250 mA on three independent channels with 16-bit resolution. Both devices feature a narrow 1/f noise bandwidth of 1 Hz, enabling magnetic field manipulation for high-performance OPMs. They exhibit a low noise of 146 pA/Hz and 4.1 nA/Hz, which translates to 15 and 16 ppb/Hz noise relative to full scale.
Assuntos
Cinchona/química , Malária/história , Fitoterapia/história , Extratos Vegetais/história , Quinina/história , História do Século XVIII , História do Século XIX , História do Século XX , Humanos , Malária/prevenção & controle , Malária/terapia , Casca de Planta , Extratos Vegetais/uso terapêutico , Quinina/uso terapêuticoRESUMO
AIM: To emphasise the importance of careful observations and demonstrate that significant conditions may, on occasion, be detected during blood donation. BACKGROUND: Venepunctures, the bread and butter of blood donor services, can be difficult procedures. We describe an unusual presentation of a relatively rare disease detected during routine blood donations because of difficult venepunctures. METHODS: Case report. RESULTS: A growth hormone-secreting pituitary adenoma was diagnosed, and successfully treated, following the initial observation of hard-to-puncture skin during blood donations. CONCLUSIONS: Seemingly trivial abnormalities may prove clinically important. One presentation of acromegaly is hard-to-puncture skin.