Psicose associada à tireotoxicose: relato de caso / Psychosis associated with thyrotoxicosis: a case report

Pacientes com tireotoxicose podem cursar com alterações psiquiátricas como depressão, mania ou psicose aguda. O objetivo deste trabalho é relatar o caso de paciente com sintomatologia psiquiátrica como manifestação de hipertireoidismo. O diagnóstico correto foi feito após anamnese e exame físico e investigação laboratorial que incluiu a função tireoidiana. Foi realizada breve revisão bibliográfica sobre a ocorrência de alterações psiquiátricas associadas à tireotoxicose. O diagnóstico de doença tireoidiana deve ser considerado sempre diante de alterações classificadas como psiquiátricas agudas.

Patients with thyrotoxicosis may suffer from psychiatric disorders, such as depression, mania or acute psychosis. This paper aims at reporting on the case of a patient with psychiatric symptomatology as manifestation of hyperthyroidism. The correct diagnosis built on physical examination and anamnesis, as well as laboratory examination including thyroid function tests. A brief review of the literature is also reported to gain a better understanding of the occurrence of psychiatric disorders associated to thyrotoxicosis. As this paper shows, diagnosis of thyroid diseases should also account for acute psychiatric disorders.

Past provoking venous thrombosis risk situations on the risk of a recurrent thrombotic event: a cohort study.

OBJECTIVE: Strategies that can classify the risk for recurrent venous thrombosis are needed. Some patients may have experienced many risk situations during their life time without developing venous thrombosis (VT), while others may have experienced few of such risk factors and then develop VT idiopathically or after a single provoked risk factor. We hypothesized that those who had 'survived' many risk situations without developing VT would, after a first VT, have a low recurrence risk. METHODS: Brazilian tertiary hospital cohort was followed for an average of 30 months after anticoagulation withdrawal for a first VT. Patients with indication for indefinite anticoagulation were not included. The primary end point was objective recurrent VT. RESULTS: Recurrent VT was recorded in 7% of 378 eligible patients. Patients with a provoked first event and positive past risk situations for VT had an incidence rate of recurrence of 1.16 (95% confidence interval [CI], 0.47-2.39) per 100 patient-years. The incidence rate ratio (IRR) of this subgroup compared to patients with a provoked event without other past risk situations for VT was 1.1 (95% CI, 0.3-4.4). This IRR was 3.3 (95% CI, 1.3-8.7) in patients with an unprovoked event and positive past risk situations and 5.1 (95% CI, 1.6-16.1) in patients with an unprovoked event and no past risk situations. CONCLUSIONS: Asking a patient about past exposure of venous thrombosis risk factors long before the occurrence of a first venous thrombosis occurred, does not provide information to classify patients at lower risk for recurrence of venous thrombosis.

Causalgia após trauma por projétil de arma de fogo: relato de caso / Post-traumatic causalgia due to firearm projectiles: case report

Causalgia é um tipo de doença neurológica crônica pertencente à Síndrome Dolorosa Regional Complexa, normalmente associada ao trauma. A sintomatologia é caracterizada por dor espontânea em queimação, hiperalgesia, edema, instabilidade vasomotora, alteração da função motora e anormalidades autonômicas. É rara, pouco conhecida e envolve várias teorias acerca de sua fisiopatologia. São descritas neste trabalho as manifestações de paciente masculino, de 20 anos, atendido no Pronto Socorro do Hospital Risoleta Tolentino Neves, vítima de múltiplas lesões por projéteis de arma de fogo, que evoluiu com manifestações compatíveis com causalgia.

Causalgia is a kind of chronic neurological disorder which is part of the Complex Regional Pain Syndrome, usually associated to trauma. Its symptoms are severe burning pain, hyperalgesia, edema, abnormal vasomotor activity, impairment of motor function and autonomic dysfunction. It is a rare, poorly known disease, which involves various theories in regard to its physiopathology. We report, in this article, a clinical case of a 20-year-old male patient, who was treated in the Emergency Room of Risoleta Tolentino Neves Hospital, victim of multiple lesions by firearm projectiles and evolved with symptoms compatible to the clinical features of Causalgia.