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1.
Biom J ; 58(2): 303-19, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24962713

RESUMO

Survey data often contain measurements for variables that are semicontinuous in nature, i.e. they either take a single fixed value (we assume this is zero) or they have a continuous, often skewed, distribution on the positive real line. Standard methods for small area estimation (SAE) based on the use of linear mixed models can be inefficient for such variables. We discuss SAE techniques for semicontinuous variables under a two part random effects model that allows for the presence of excess zeros as well as the skewed nature of the nonzero values of the response variable. In particular, we first model the excess zeros via a generalized linear mixed model fitted to the probability of a nonzero, i.e. strictly positive, value being observed, and then model the response, given that it is strictly positive, using a linear mixed model fitted on the logarithmic scale. Empirical results suggest that the proposed method leads to efficient small area estimates for semicontinuous data of this type. We also propose a parametric bootstrap method to estimate the MSE of the proposed small area estimator. These bootstrap estimates of the MSE are compared to the true MSE in a simulation study.


Assuntos
Bioestatística/métodos , Modelos Lineares
3.
Stat Methods Med Res ; 24(3): 373-95, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24492792

RESUMO

A new semiparametric approach to model-based small area prediction for counts is proposed and used for estimating the average number of visits to physicians for Health Districts in Central Italy. The proposed small area predictor can be viewed as an outlier robust alternative to the more commonly used empirical plug-in predictor that is based on a Poisson generalized linear mixed model with Gaussian random effects. Results from the real data application and from a simulation experiment confirm that the proposed small area predictor has good robustness properties and in some cases can be more efficient than alternative small area approaches.


Assuntos
Pesquisas sobre Atenção à Saúde/métodos , Inquéritos Epidemiológicos/métodos , Modelos Estatísticos , Tamanho da Amostra , Idoso , Atenção à Saúde/estatística & dados numéricos , Pesquisas sobre Atenção à Saúde/estatística & dados numéricos , Nível de Saúde , Inquéritos Epidemiológicos/estatística & dados numéricos , Humanos , Itália/epidemiologia , Funções Verossimilhança , Distribuição de Poisson , Análise de Regressão , Estudos de Amostragem , Inquéritos e Questionários
4.
Stat Med ; 33(27): 4805-24, 2014 Nov 30.
Artigo em Inglês | MEDLINE | ID: mdl-25042758

RESUMO

We introduce a semi-parametric approach to ecological regression for disease mapping, based on modelling the regression M-quantiles of a negative binomial variable. The proposed method is robust to outliers in the model covariates, including those due to measurement error, and can account for both spatial heterogeneity and spatial clustering. A simulation experiment based on the well-known Scottish lip cancer data set is used to compare the M-quantile modelling approach with a disease mapping approach based on a random effects model. This suggests that the M-quantile approach leads to predicted relative risks with smaller root mean square error. The paper concludes with an illustrative application of the M-quantile approach, mapping low birth weight incidence data for English Local Authority Districts for the years 2005-2010.


Assuntos
Distribuição Binomial , Mapeamento Geográfico , Análise de Regressão , Análise Espacial , Simulação por Computador , Inglaterra , Métodos Epidemiológicos , Humanos , Recém-Nascido de Baixo Peso , Recém-Nascido , Neoplasias Labiais/epidemiologia , Método de Monte Carlo , Fatores de Risco , Escócia/epidemiologia
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