RESUMO
The presence of Chlamydia trachomatis and human papillomavirus (HPV) was evaluated by PCR technique in 189 sexually active women, between 15 and 58 years old, with cytological abnormalities in their uterine cervical epithelium and belonging to a region of Argentina with high incidence of cervical cancer. Risk factors in relation to chlamydial infection were also analyzed. Total prevalence for C. trachomatis infection was 24.9%, but there was a significant difference between prevalence in low socio-economical level (32.9%) and high or medium socio-economical level (17.7%). Total prevalence for DNA of HPV was 52.9%, but women infected with C. trachomatis showed a higher risk for viral infection than non-infected ones (OR = 2.27 / CI 95% = 1.10-4.73), with statistical significant difference (p = 0.016).(AU)
Assuntos
Adolescente , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Colo do Útero/microbiologia , Infecções por Chlamydia/epidemiologia , Chlamydia trachomatis , Papillomaviridae , Infecções por Papillomavirus/epidemiologia , Argentina/epidemiologia , Carcinoma/diagnóstico , Colo do Útero/patologia , Colo do Útero/virologia , Infecções por Chlamydia/diagnóstico , Chlamydia trachomatis/isolamento & purificação , Genótipo , Papillomaviridae/isolamento & purificação , Infecções por Papillomavirus/diagnóstico , Reação em Cadeia da Polimerase , Polimorfismo de Fragmento de Restrição , Prevalência , Fatores de Risco , Neoplasias do Colo do Útero/diagnóstico , Esfregaço VaginalRESUMO
The presence of Chlamydia trachomatis and human papillomavirus (HPV) was evaluated by PCR technique in 189 sexually active women, between 15 and 58 years old, with cytological abnormalities in their uterine cervical epithelium and belonging to a region of Argentina with high incidence of cervical cancer. Risk factors in relation to chlamydial infection were also analyzed. Total prevalence for C. trachomatis infection was 24.9%, but there was a significant difference between prevalence in low socio-economical level (32.9%) and high or medium socio-economical level (17.7%). Total prevalence for DNA of HPV was 52.9%, but women infected with C. trachomatis showed a higher risk for viral infection than non-infected ones (OR = 2.27 / CI 95% = 1.10-4.73), with statistical significant difference (p = 0.016).(AU)
Assuntos
Adolescente , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Colo do Útero/microbiologia , Infecções por Chlamydia/epidemiologia , Chlamydia trachomatis , Papillomaviridae , Infecções por Papillomavirus/epidemiologia , Argentina/epidemiologia , Carcinoma/diagnóstico , Colo do Útero/patologia , Colo do Útero/virologia , Infecções por Chlamydia/diagnóstico , Chlamydia trachomatis/isolamento & purificação , Genótipo , Papillomaviridae/isolamento & purificação , Infecções por Papillomavirus/diagnóstico , Reação em Cadeia da Polimerase , Polimorfismo de Fragmento de Restrição , Prevalência , Fatores de Risco , Neoplasias do Colo do Útero/diagnóstico , Esfregaço VaginalRESUMO
The presence of Chlamydia trachomatis and human papillomavirus (HPV) was evaluated by PCR technique in 189 sexually active women, between 15 and 58 years old, with cytological abnormalities in their uterine cervical epithelium and belonging to a region of Argentina with high incidence of cervical cancer. Risk factors in relation to chlamydial infection were also analyzed. Total prevalence for C. trachomatis infection was 24.9%, but there was a significant difference between prevalence in low socio-economical level (32.9%) and high or medium socio-economical level (17.7%). Total prevalence for DNA of HPV was 52.9%, but women infected with C. trachomatis showed a higher risk for viral infection than non-infected ones (OR = 2.27 / CI 95% = 1.10-4.73), with statistical significant difference (p = 0.016).
Assuntos
Adolescente , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Chlamydia trachomatis , Colo do Útero/microbiologia , Infecções por Chlamydia/epidemiologia , Infecções por Papillomavirus/epidemiologia , Papillomaviridae , Argentina/epidemiologia , Carcinoma/diagnóstico , Chlamydia trachomatis/isolamento & purificação , Colo do Útero/patologia , Colo do Útero/virologia , Genótipo , Infecções por Chlamydia/diagnóstico , Infecções por Papillomavirus/diagnóstico , Neoplasias do Colo do Útero/diagnóstico , Reação em Cadeia da Polimerase , Polimorfismo de Fragmento de Restrição , Prevalência , Papillomaviridae/isolamento & purificação , Fatores de Risco , Esfregaço VaginalRESUMO
Noble-gas geochemistry is an important tool for understanding planetary processes from accretion to mantle dynamics and atmospheric formation. Central to much of the modelling of such processes is the crystal-melt partitioning of noble gases during mantle melting, magma ascent and near-surface degassing. Geochemists have traditionally considered the 'inert' noble gases to be extremely incompatible elements, with almost 100 per cent extraction efficiency from the solid phase during melting processes. Previously published experimental data on partitioning between crystalline silicates and melts has, however, suggested that noble gases approach compatible behaviour, and a significant proportion should therefore remain in the mantle during melt extraction. Here we present experimental data to show that noble gases are more incompatible than previously demonstrated, but not necessarily to the extent assumed or required by geochemical models. Independent atomistic computer simulations indicate that noble gases can be considered as species of 'zero charge' incorporated at crystal lattice sites. Together with the lattice strain model, this provides a theoretical framework with which to model noble-gas geochemistry as a function of residual mantle mineralogy.
