Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Hum Psychopharmacol ; 22(2): 81-8, 2007 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17295197

RESUMO

Previous research draws parallels between ecstasy-related and age-related deficits in cognitive functioning. Age-related impairments in working memory have been attributed to a slow down in information processing speed. The present study compared 29 current ecstasy users, 10 previous users and 46 non-users on two tests measuring information processing speed and a computation span task measuring working memory. Results showed that ecstasy users performed worse than non-ecstasy users in the letter comparison task although the overall difference was not significant (p=0.089). Results from the pattern recognition task showed that current ecstasy users produced significantly more errors than the other two groups (p<0.01). When results were combined for both the letter and pattern tasks, once again current ecstasy users produced significantly more errors than non-ecstasy users (p<0.01). Working memory deficits obtained were statistically significant with both ecstasy using groups performing significantly worse than non-users on the computation span measure (p<0.01). Moreover, ANCOVA with measures of processing speed as covariates failed to eliminate the group difference in computation span (p<0.01). Therefore, it is likely the mechanism responsible for impairments in the computation span measure is not the same as that in elderly adults where processing speed generally removes most of the age-related variance. Also of relevance is the fact that the ecstasy users reported here had used a range of other drugs making it difficult to unambiguously attribute the results obtained to ecstasy use.


Assuntos
N-Metil-3,4-Metilenodioxianfetamina/administração & dosagem , Transtornos Relacionados ao Uso de Substâncias/fisiopatologia , Adulto , Anfetamina/administração & dosagem , Cannabis/química , Cocaína/administração & dosagem , Etanol/administração & dosagem , Humanos , Memória/efeitos dos fármacos , Processos Mentais/efeitos dos fármacos , Análise Multivariada , Reconhecimento Visual de Modelos/efeitos dos fármacos , Desempenho Psicomotor/efeitos dos fármacos , Reprodutibilidade dos Testes , Autoadministração , Transtornos Relacionados ao Uso de Substâncias/psicologia , Inquéritos e Questionários , Fatores de Tempo
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...