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1.
J Radiol Prot ; 34(1): 161-81, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24441764

RESUMO

A new radioactive substances regulatory regime came into effect across the UK on 1 October 2011, accompanied by Government and regulator's guidance. The legislation sets new activity thresholds for what is within its scope and for what is exempt from the permitting requirements. These thresholds are, for the first time, clearly based on the levels in the Basic Safety Standards Directive; distinguish between NORM industrial activities and practices; and are derived from different dose constraints. There are new exemption provisions for NORM, aqueous liquids and gaseous wastes.


Assuntos
Poluentes Radioativos , Resíduos Radioativos/legislação & jurisprudência , Gerenciamento de Resíduos/legislação & jurisprudência , Reino Unido
2.
J Radiol Prot ; 31(3): 309-17, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21865612

RESUMO

Over the past 50 years a comprehensive regulatory framework for radioactive substances in the UK has been progressively introduced, important initial milestones being the white paper Cmnd 884 and the Radioactive Substances Act 1960. During the 1970s and 1980s there were a succession of enquiries and white papers which developed from the growing awareness of the problems of the nuclear waste legacy. This was followed by a comprehensive policy white paper in 1995: Cm 2919. In 1990, 1993, 1995 and 2005 some aspects of the 1960 Act were updated. The most recent, and most radical, modernisation took place in 2010, when the Act was incorporated into the Environmental Permitting Regulations, in England and Wales. Currently a major review of the exemption orders and exclusion criteria under the radioactive substances legislation is close to completion, which will complete the current phase of modernisation of the regulatory framework.


Assuntos
Resíduos Radioativos/legislação & jurisprudência , Gerenciamento de Resíduos/legislação & jurisprudência , Proteção Radiológica , Reino Unido
3.
Biosci Biotechnol Biochem ; 74(9): 1760-9, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20834175

RESUMO

The status quo of flavonoid biosynthesis as it relates to flower color is reviewed together with a success in modifying flower color by genetic engineering. Flavonoids and their colored class compounds, anthocyanins, are major contributors to flower color. Many plant species synthesize limited kinds of flavonoids, and thus exhibit a limited range of flower color. Since genes regulating flavonoid biosynthesis are available, it is possible to alter flower color by overexpressing heterologous genes and/or down regulating endogenous genes. Transgenic carnations and a transgenic rose that accumulate delphinidin as a result of expressing a flavonoid 3',5'-hydroxylase gene and have novel blue hued flowers have been commercialized. Transgenic Nierembergia accumulating pelargonidin, with novel pink flowers, has also been developed. Although it is possible to generate white, yellow, and pink-flowered torenia plants from blue cultivars by genetic engineering, field trial observations indicate difficulty in obtaining stable phenotypes.


Assuntos
Flavonoides/biossíntese , Flores/genética , Engenharia Genética/métodos , Vias Biossintéticas/genética , Cor , Flavonoides/genética , Plantas Geneticamente Modificadas/genética
4.
Int J Mol Sci ; 10(12): 5350-5369, 2009 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-20054474

RESUMO

Genetically-modified, colour-altered varieties of the important cut-flower crop carnation have now been commercially available for nearly ten years. In this review we describe the manipulation of the anthocyanin biosynthesis pathway that has lead to the development of these varieties and how similar manipulations have been successfully applied to both pot plants and another cut-flower species, the rose. From this experience it is clear that down- and up-regulation of the flavonoid and anthocyanin pathway is both possible and predictable. The major commercial benefit of the application of this technology has so far been the development of novel flower colours through the development of transgenic varieties that produce, uniquely for the target species, anthocyanins derived from delphinidin. These anthocyanins are ubiquitous in nature, and occur in both ornamental plants and common food plants. Through the extensive regulatory approval processes that must occur for the commercialization of genetically modified organisms, we have accumulated considerable experimental and trial data to show the accumulation of delphinidin based anthocyanins in the transgenic plants poses no environmental or health risk.


Assuntos
Biotecnologia/métodos , Flores/genética , Engenharia Genética , Pigmentação/genética , Antocianinas/biossíntese , Dianthus/genética , Dianthus/metabolismo , Flavonoides/metabolismo , Flores/metabolismo , Plantas Geneticamente Modificadas/genética , Plantas Geneticamente Modificadas/metabolismo , Rosa/genética , Rosa/metabolismo
5.
J Psycholinguist Res ; 37(4): 259-68, 2008 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-18344001

RESUMO

Skousen's (1989, Analogical modeling of language, Kluwer Academic Publishers, Dordrecht) Analogical Model (AM) predicts behavior such as spelling pronunciation by comparing the characteristics of a test item (a given input word) to those of individual exemplars in a data set of previously encountered items. While AM and other exemplar-based models enjoy continuing success in their ability to predict what a participant's response to a given task will be, it does not yet include a widely tested mechanism for extending its predictions to other measures of interest in psycholinguistics such as response time (RT). This article reports the results of applying a formula derived in Estes (1959, in: Koch, Psychology: A study of a science, McGraw-Hill Book Co., Inc.) for approximating "mean predicted latency" in decision tasks to the alternative responses and their associated probabilities predicted by AM. The model is tested against six sets of data from previously published naming studies.


Assuntos
Vocabulário , Humanos , Estudos Prospectivos
6.
J Am Coll Health ; 56(2): 159-63, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17967762

RESUMO

UNLABELLED: College students are at high risk for human papillomavirus (HPV) infection, yet their knowledge and self-protective behaviors appear inadequate. Researchers who have measured HPV-related knowledge and behaviors in evaluating college intervention efforts pay secondary attention to black college students because this group generally represents only a small subset of samples of the broader college population. OBJECTIVE AND PARTICIPANTS: The authors' purpose in this study was to examine HPV-related knowledge and behaviors in 351 black undergraduates attending a historically black southeastern university in the spring of 2003. METHODS: Voluntary and anonymous student participation was solicited in randomly selected undergraduate classes. RESULTS: Results indicated that most students lacked HPV awareness (64%), became aware of HPV largely after infection, and gained their HPV knowledge from a health-care provider or college class. The authors performed an analysis by gender and found that women were more knowledgeable about HPV than were men. Observed HPV-related knowledge and behaviors were similar to samples of the broader US college population. CONCLUSIONS: Findings suggest a greater need for HPV intervention efforts for all college students, including those at black colleges.


Assuntos
Negro ou Afro-Americano/educação , Conhecimentos, Atitudes e Prática em Saúde , Infecções por Papillomavirus/etnologia , Estudantes/psicologia , Universidades , Adolescente , Adulto , Negro ou Afro-Americano/psicologia , Feminino , Educação em Saúde , Humanos , Masculino , Infecções por Papillomavirus/etiologia , Infecções por Papillomavirus/prevenção & controle , Setor Público , Assunção de Riscos , Fatores Sexuais , Comportamento Sexual/psicologia , Comportamento Sexual/estatística & dados numéricos , Doenças Virais Sexualmente Transmissíveis/etnologia , Doenças Virais Sexualmente Transmissíveis/etiologia , Doenças Virais Sexualmente Transmissíveis/prevenção & controle , Sudeste dos Estados Unidos/epidemiologia , Serviços de Saúde para Estudantes , Estudantes/estatística & dados numéricos , Inquéritos e Questionários
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