RESUMO
Cystic hypersecretory lesions of the breast are a spectrum of conditions ranging from cystic hypersecretory hyperplasia with atypia and invasive cystic hypersecretory carcinoma (CHC). It is a subtype of ductal carcinoma of the breast. The tumour is very infrequent and hence, extensive literature is limited. This culminates in the fact that it does not feature as part of the WHO classification of breast tumours. However, a good knowledge about its distinct pathological features can avert misdiagnosis and help differentiate CHC from other conditions. Thus far, only 22 cases of invasive CHC have been reported, of which 3 were microinvasive. Only 7 cases of axillary lymph node metastasis have been documented. We report a case of invasive CHC of the breast that was metastatic to the axilla and refractory to neoadjuvant chemotherapy. Our case report aims to add to the literature on the disease, aiming to support large-scale studies in the future in order to elaborate on its clinical and biological characteristics.
RESUMO
Inflammatory bowel disease is fast becoming a disease of the East. Of all its entities, Crohn's disease is the most diverse and debilitating due to its nature of transmural granulomatous inflammation. The clinical picture varies according to the disease location and severity. This translates to tailoring the treatment according to individual disease. The management should be predominantly medical since recurrence rates post-surgery are objectionable. But surgery, as a measure to tackle complications under cover of adequate medical and nutritional therapy, can be lifesaving. Herein, we describe a series of seven cases where surgery was crucial in the management of Crohn's disease.
