1.
Phytother Res
; 17(4): 420-1, 2003 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12722155
RESUMO
Wedelolactone (WL) and demethylwedelolactone (DWL) isolated from Eclipta alba were tested in the trypsin inhibition bioassay (in vitro). Both compounds showed potent activity. IC(50) values of WL and DWL were found to be 2.9 and 3.0 microg/mL respectively.
Assuntos
Cumarínicos/farmacologia , Eclipta , Fitoterapia , Inibidores de Proteases/farmacologia , Tripsina/efeitos dos fármacos , Animais , Galinhas , Humanos , Concentração Inibidora 50 , Óvulo/efeitos dos fármacos , Extratos Vegetais/farmacologia
2.
Phytother Res
; 16(2): 197-8, 2002 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11933129
RESUMO
Successive petroleum ether, chloroform, ethanol and water extracts, a saponin rich fraction (SRF) and bacoside A isolated from Bacopa monnieri were tested for brine shrimp lethality. Successive ethanol extracts and SRF showed potent activity. Bacoside A showed the maximum activity with a LC(50) of 38.3 microg/mL. The results confirmed the previous reports of an anticancer effect of Bacopa monnieri and suggest bacoside A as the active constituent.
