1.
J Org Chem
; 86(9): 6918-6926, 2021 05 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33852298
RESUMO
The highly regioselective N-alkylation reaction of 2-pyridones was achieved through hydrazone chemistry, especially for substrates with bulky secondary alkyl groups. Described herein is a copper-catalyzed coupling reaction of pyridone derivatives with tosylhydrazones.