Relationship between gene polymorphism of inhaled glucocorticosteroids budesonide and efficacy in asthma / 中国临床药理学与治疗学

AIM: To investigate the relationship among the rs37973 polymorphism of glucocorticoid induced transcription factor 1 (GLCCI1) gene, the rs1876828 polymorphism of corticotropin-hormone receptor 1 (CRHR1) gene, the rs28364072 polymorphism of Fc fragment of IgE receptor II (FCER2) gene and the response to inhaled corticosteroids (ICS) budesonide in patients with asthma. METHODS: 152 blood samples of patients with asthma were collected. The DNA were studied by blood samples. Fluorescence in situ hybridization method was used to detect the polymorphism of GLCCI1, CRHR1, FCER2. Lung function index of the ICS before and after treatment, such as forced vital capacity (FVC), first second forced breath volume (FEV

The application of homogenate diet and yogurt in critical ill patients / 肠外与肠内营养

Objective: To investigate the methods and result of enteral nutritional treatment using homogenate diet and yogurt in critical ill patients.Methods: Four hundreds critical ill patients in ICU were divided randomly into two groups: treatment group(homogenate diet and yogurt) and control group(homogenate diet).Results: The nutrition status of the treatment group was higher than that of the control group.The treatment group had a lower incidence of gastrointestinal complication and a better prognosis compared with those of control group.Conclusion: The homogenate diet and yogurt would improve the nutritional condition effectively,decrease the gastrointestinal complications and increase the survival rate.