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Endoscopy ; 51(6): 540-547, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-30347424

RESUMO

BACKGROUND: Endoscopic ultrasound-guided biliary drainage is an alternative to percutaneous biliary drainage in cases of malignant biliary obstruction and failure of classic endoscopic drainage by endoscopic retrograde cholangiopancreatography (ERCP). Recently, a new electrocautery-enhanced lumen-apposing metal stent (ECE-LAMS) that allows for endoscopic anastomosis (apposition stent) has become available for use in EUS-choledochoduodenostomy (EUS-CDS) and facilitates the procedure. METHODS: This was a retrospective study of all EUS-CDS procedures performed in France between April 2016 and August 2017. The primary end point was the technical and clinical success rates of EUS-CDS using an ECE-LAMS. RESULTS: 52 consecutive patients were included in the study. The etiology of distal bile duct obstruction was distal pancreatic adenocarcinoma in 43 patients (82.7 %). The technical success rate was 88.5 % (46 /52 patients), and the clinical success rate was 100 % (46/46 patients). The mean duration of the procedure was 10.2 minutes (range 1 - 90). Two patients (3.8 %) presented with short-term complications after EUS-CDS and before discharge from hospital. In univariate analyses, a small diameter of the common bile duct and not following the recommended procedure technique were significant risk factors for technical failure. Over a mean follow-up of 157 days, the median survival time without biliary complications was 135 days. CONCLUSION: EUS-CDS with an ECE-LAMS is efficacious and safe in distal malignant obstruction of the common bile duct and could be proposed as the first option in cases of ERCP failure.


Assuntos
Coledocostomia/métodos , Colestase/cirurgia , Eletrocoagulação , Endoscopia do Sistema Digestório/métodos , Ultrassonografia de Intervenção , Idoso , Idoso de 80 Anos ou mais , Colestase/etiologia , Drenagem/métodos , Feminino , França , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Pancreáticas/complicações , Punções , Estudos Retrospectivos , Stents
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