Efficient Process for the Production of Alkyl Esters.

This article reports a scalable process development for the production of alkyl esters through the esterification route by utilizing fly ash as a catalyst. The catalyst consisting of mixed oxides such as alumina, iron oxide, calcium oxide, magnesium oxide, and silica was employed for the esterification reaction without modification. The catalyst was evaluated for the conversion of feedstock containing variable amounts of free fatty acids, mono/dibasic acid, and alcohol/polyols into the corresponding alkyl esters. Three types of fly ash catalysts, viz., FS-1, FP-1, and FC-1, were chosen from three different industrial sources. Synthesis of dimethyl adipate was studied as a model reaction. FS-1 fly ash gave the highest yield of dimethyl adipate, whereas FC-1 gave a low yield of dimethyl adipate. The recyclability of FS-1 was evaluated for three cycles, and no loss of yield was observed. Furthermore, the catalyst FS-I was found to be capable of producing good yields for various esterification reactions with different substrates.

Synthesis of 2,3,4-Trisubstituted 2-Cyclopentenones via Sequential Functionalization of 2-Cyclopentenone.

The synthesis of differently substituted 2,3,4-triarylcyclopent-2-en-1-ones from 2-cyclopentenone via sequential functionalization of a novel 2,4-dibromo-3-(4-methoxyphenyl) cyclopent-2-en-1-one intermediate has been developed. The process provides access to selective arylation at C-4 and C-2 with a broader substrates scope, which includes heteroaryl and alkyl substitution at C-2.