The isolated perfused kidney: an in vitro test system for evaluation of renal tissue damage induced by high-energy shockwaves sources.

Most of our knowledge of shockwave-induced renal damage is based on animal experiments and clinical observation. We developed a tissue model using isolated porcine kidneys perfused with Berliner Blau dye in physiologic saline using a Ureteromat Perez-Castro peristaltic pump connected to the renal artery. Reproducible results were obtained under a variety of experimental conditions. Further refinements of the model might consist of interposition of tissue layers in the shockwave path or simulation of ventilatory movements.

[Demonstration of T-cell activation using synthetic polynucleotides]. / Nachweis der T-Zell aktivierenden Funktion von synthetischen Polynukleotiden

The present data show that SPN have a striking influence on thymus dependent T cells. The enhancing effect of gvh reactions on antibody formation against thymus dependent antigens give a good explanation for the antitumor effects of this substance.

[Effect of active interferonization and anti-thymocyte globulin on the growth of virus-induced hamster melanoma A-Mel-S]. / Der Einfluss einer aktiven Interferonisierung und der Einfluss von Anti-Thymozyten-Globulin auf das Wachstum des Virus induzierten Hamstermelanoms A-Mel-S

The present data show that biological and synthetic inducers of interferon are able to reduce the growth of a transplantable malignant melanoma in the Syrian hamster. The advantage of the biological inducer H-MP are that it is not toxic for humans and that a high titer of interferon can be maintained over a long period of time.

[Thermography: a method for the assessment of rejection time in skin transplants]. / Thermographie: eine Methode zur Objektivierung der Abstossungszeit von Hauttransplantaten

It is possible to register the rejection time of allografts quantitatively by the method of thermography. Results are congruent with a micromorphological state, but only partially with the macroscopic pictures.