RESUMO
INTRODUCTION: We performed a meta-analysis to evaluate the impact of nutritional potassium limitation on serum potassium change, and death in chronic kidney disease. METHODS: A systematic literature search up to October 2021 was carried out and eight studies included 92 558 subjects with chronic kidney disease at the start of the study; 41 474 of them were provided with nutritional potassium limitation and 510 084 were nonrestricted diet. RESULTS: Nutritional potassium limitation had significantly lower serum potassium change (MD, -0.33; 95% CI, -0.58 to -0.07; p = 0.01) compared to nonrestricted diet in subjects with chronic kidney disease. However, nutritional potassium limitation had no significant impact on the death (OR, 0.80; 95% CI, 0.58-1.10; p = 0.17) compared to nonrestricted diet in subjects with chronic kidney disease. CONCLUSION: Nutritional potassium limitation had significantly lower serum potassium change compared to nonrestricted diet in subjects with chronic kidney disease. Further studies are required to validate these findings.
