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1.
J Am Med Dir Assoc ; 21(9): 1346-1348, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32723534

RESUMO

In recent years, subacute care units (SCUs) have emerged as alternatives to acute hospitalization for selected emergency department (ED) patients who might benefit from a short period of inpatient stay within a less acute setting. We developed a new protocol to directly admit selected older patients from our acute hospital's (AH) ED to the SCU of a partner community hospital, making use of our ED's short-stay ward as a transit area to overcome administrative, financial, and clinical barriers. The new protocol has removed the need for intervening stays of longer than 24 hours at our AH, reduced overall length of stay across both institutions, decreased hospital admissions, and reduced the number of patient hand-offs.


Assuntos
Serviço Hospitalar de Emergência , Cuidados Semi-Intensivos , Hospitalização , Hospitais Comunitários , Humanos , Tempo de Internação , Admissão do Paciente
2.
Nat Commun ; 4: 1426, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23385571

RESUMO

Chinese tree shrews (Tupaia belangeri chinensis) possess many features valuable in animals used as experimental models in biomedical research. Currently, there are numerous attempts to employ tree shrews as models for a variety of human disorders: depression, myopia, hepatitis B and C virus infections, and hepatocellular carcinoma, to name a few. Here we present a publicly available annotated genome sequence for the Chinese tree shrew. Phylogenomic analysis of the tree shrew and other mammalians highly support its close affinity to primates. By characterizing key factors and signalling pathways in nervous and immune systems, we demonstrate that tree shrews possess both shared common and unique features, and provide a genetic basis for the use of this animal as a potential model for biomedical research.


Assuntos
Genoma/genética , Tupaia/genética , Animais , China , Variação Genética , Hepacivirus/fisiologia , Hepatite C/genética , Hepatite C/virologia , Humanos , Sistema Imunitário/metabolismo , Inativação Metabólica/genética , Camundongos , Sistema Nervoso/metabolismo , Filogenia , Análise de Sequência de DNA , Tupaia/imunologia
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