Construction of BiOCl/Ti-MOFs type-II heterojunction photocatalyst for enhanced photocatalytic performance for multiple antibiotics removal.

The increased threats to environmental and human health caused by the widespread use of antibiotics have increased the need for efficient technologies for removing antibiotic remnants from wastewater after production. Photocatalysis, which is non-toxic, highly efficient, and low energy consumption, has played a vital role in wastewater treatment among the aforementioned technologies. Therefore, a MIL-125(Ti)/BiOCl type-II heterojunction photocatalyst was fabricated using solvothermal method. Investigations remarkably revealed that the enhanced photocatalytic performance of the photocatalyst for multiple antibiotics degradation (tetracycline and ofloxacin) was attributed to the construction of a heterojunction, which inhibits carrier recombination and enhances visible-light absorption. Furthermore, the radical trapping experiments and electron spin resonance determined superoxide radicals and holes to be the main species in the photocatalytic process. Finally, we presented a potential photocatalytic mechanism that could account for the observations. Overall, this study offered guidelines for developing more photocatalysts with visible-light responses and removing multiple antibiotics from water more efficiently.

Protection of pigs against Taenia solium cysticercosis using recombinant antigen or in combination with DNA vaccine.

In the present study, we investigated the duration of protection afforded to pigs immunized in two different prime-boost regimens: one is homologus priming and boosting with a protein vaccine, and the other is priming with a DNA vaccine and boosting with the protein vaccine. Groups of pigs that received the same vaccination regimen were then challenged with Taenia solium eggs at 6, 12 or 20 weeks post-immunization (wpi), respectively. The results showed that all vaccinated pigs challenged at 6 or 12 wpi showed significant (P < 0.05) reduction in the development of cysts. When challenged at 20 wpi, pigs primed with the DNA vaccine (pcDNA3-cC1) followed by two boosters of the protein vaccine (GST-cC1) showed significant (P < 0.05) protection against the challenge of T. solium eggs, whereas pigs receiving three injections of the protein vaccine showed no significant protection compared to non-vaccinated controls (P > 0.05). Antibody isotype assays showed that DNA prime-protein boost regimen induced a predominantly IgG2 response, compared to an IgG1 biased response for the protein prime-protein boost regimen. In addition, peripheral blood mononuclear cells (PBMC) obtained from the DNA prime-protein boost group proliferated strongly in response to GST-cC1 protein, and this responsiveness persisted until 20 wpi. Taken together, our data suggest that the use of a prime-boost strategy combining DNA and protein vaccines may be better than protein alone for the longevity of protection against the challenge of T. solium eggs.