RESUMO
Objective: The objective of this study was to examine the impact of hemiplegic limb rehabilitation training on the nursing care of individuals who have experienced a stroke. Methods: Seventy-six stroke patients from Zhangjiagang Hospital of Traditional Chinese Medicine participated in a study comparing the effects of different nursing interventions. The patients were divided into 2 groups: a control that received standard nursing care and an observation group that received rehabilitation training in addition to standard care. The researchers analyzed the effects on limb movement, daily activities, muscle recovery, and nursing satisfaction between the 2 groups. Results: The nursing intervention in the observation group showed a significantly higher effectiveness rate of 94.74% compared to the control group's rate of 55.26% (P < .05). Prior to the intervention, there was no notable difference in limb movement scores between the 2 groups (P > .05). Similarly, there was no significant difference in Barthel Index scores between the 2 groups before the intervention (P > .05). However, after the intervention, the Bathel Index score in the observation group was significantly higher than that of the control group (P < .05). Conclusion: Hemiplegic limb rehabilitation training nursing care positively impacts stroke patients, improving physical mobility, muscle strength, and overall quality of life. This method should be prioritized and implemented in clinical practice.
RESUMO
The present study aimed to investigate the expression and predictive value of serum hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in patients with burns following treatment. A total of 84 patients with burns treated in Jinan City People's Hospital (Jinan, China) between June 2015 and August 2017 were selected and their clinical information was collected. The expression levels of HIF-1α and VEGF before and after treatment were detected via ELISA, and HIF-1α and VEGF levels in patients with effective and ineffective treatment were compared. The predictive values of HIF-1α and VEGF in clinical efficacy were determined using receiver operating characteristic (ROC) curves, and independent risk factors affecting treatment inefficacy were analyzed via multivariate logistic regression. It was revealed that HIF-1α decreased significantly (P<0.05) while VEGF significantly increased in patients after treatment. Patients with effective treatment presented significantly lower HIF-1α levels and higher VEGF levels compared with those with ineffective treatment. The ROC curve indicated that the area under the curve (AUC) of HIF-1α for treatment efficacy was 0.795, the 95% CI was 0.666-0.924, the specificity and sensitivity were 68.75 and 80.88%, respectively, and the Youden index was 49.63%. For VEGF, the AUC, 95% CI, specificity, sensitivity and Youden index were 0.826, 0.725-0.928, 68.75, 82.35 and 51.10% respectively. Moreover, under the joint detection of HIF-1α and VEGF, the AUC was 0.847, 95% CI was 0.746-0.947, specificity and sensitivity were 87.50 and 66.18%, respectively, with a Youden index of 53.68%. Multivariate analysis demonstrated that higher HIF-1α level, lower VEGF level and higher burn degree before treatment were independent risk factors for treatment inefficacy. HIF-1α levels decreased and VEGF levels increased in burn patients after treatment. HIF-1α and VEGF before treatment may therefore serve as predictors for treatment efficacy.
