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Ukr Biokhim Zh ; 49(4): 103-7, 1977.
Artigo em Ucraniano | MEDLINE | ID: mdl-143099

RESUMO

It is established that the activity of Na+, K+ = ATPase and Mg2+, Ca2+ = ATPase lowers significantly at the paralytic stage of the disease. At earlier stages of the disease preceding the appearance of peculiar neurological symptoms (the seventh and fourteenth days of the incubation period) a decrease of the Mg2+, Ca2+ = ATPase activity was observed in the brain and spinal cord, whereas the Na+, K+ = ATPase activity in the brain remained at the control level up to the appearance of the disease clearly developed symptoms. The Na+, K+ = ATPase activity of the brain on the fourteenth day of the incubation period corresponded to the level of the activity at the paralytic stage of the disease.


Assuntos
Adenosina Trifosfatases/metabolismo , Sistema Nervoso Central/enzimologia , Encefalomielite Autoimune Experimental/enzimologia , Animais , Encéfalo/enzimologia , Cálcio , Encefalomielite Autoimune Experimental/complicações , Cobaias , Magnésio , Paralisia/enzimologia , Paralisia/etiologia , Potássio , Sódio , Medula Espinal/enzimologia , Fatores de Tempo
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