[Ocular hypertension: results of a 10-year follow-up study]. / Oftal'mogipertenziia: rezul'taty desiatiletnego dinamicheskogo nabliudeniia.

A multifactorial mathematical analysis with a diagnosis presented as a complex number was used in assessing results of 10-year follow-up of ophthalmic hypertension subjects. When the follow-up was over, the patients were divided into three groups by the findings at clinical examination. Group I patients (37%) recovered normal ophthalmic tone, group II patients (34%) remained hypertensive and group III (29%) developed an open angle primary glaucoma. The mathematical processing of diagnostic signs permitted an accurate diagnosis and monitoring of the process.

[Retrospective analysis of the parameters of ocular hemodynamics in patients with initial open-angle glaucoma]. / Retrospektivnyi analiz pokazatelei gemodinamiki glaz u bol'nykh nachal'noi otkrytougol'noi glaukomoi.

The authors analyze ocular hemodynamics parameters in patients with ocular hypertension who were transferred to glaucoma group during ten-year follow-up. The patients who were transferred to this group were those whose hemodynamic parameters were lower than in the reference group. By the end of the follow-up period a negligible reduction of the hemodynamic parameters was observed in the 'hypertension' group and a statistically significant reduction in glaucoma patients. This lead the authors to a conclusion on the necessity of early prescription of drugs stimulating disordered ocular hemodynamics.

Surgical stimulation of the uveoscleral outflow. Experimental studies on enucleated human eyes.

Six series of experiments were performed on 45 isolated cadaver eyes. In the first series, the outflow facility of the human sclera was measured, in the others, five surgical techniques for stimulating the uveo-scleral outflow were evaluted with the help of a constant pressure perfusion technique. It was found that the scleral C-value was pressure independent and its average value was equal to 0.0036 mm3/min/mmHg per 1 cm2 (100 mm2) of scleral surface. After the implantation of a scleral strip into the supra-uveal space, the mean increase in the total C-value was 23% of its initial value, ranging from 7 to 35%. After cyclodialysis the C-value increment varied from 17% to 66%, averaging 30%. The average increase in the outflow facility amounted to 60% (range 24--96%) in those cases where implantation of the scleral strip in the suprauveal space was combined with cyclodialysis. After implantation of a scleral strip, combined with subscleral sinusotomy, the C-value increment varied from 18 to 71%, averaging 41%. After cyclodialysis combined with goniospasis, the mean increase in the outflow facility coefficient was 62% (range 43%--108%).