[The course of pregnancy induced by ovulation stimulation in patients with the hypogonadotropic form of amenorrhea]. / Techenie beremennosti, indutsirovannoi stimuliatsiei ovuliatsii u patsientok s gipogonadotropnoi formoi amenorei.

The course of 60 pregnancies induced by ovulation stimulation with pergonal (in 46 cases) and lutrelef, an LHRF agonist (in 10 cases) was followed up. The authors emphasize the importance of the first therapeutic course as a preparative one, because pregnancies occurred in only 15 and 20% of patients treated with the two drugs, respectively, after it, and 25% of them failed to develop. The major pregnancy complications were due to multiple fetuses (23.4 and 20%, respectively). Stimulated pregnancy should be regarded as a high risk one in respect of spontaneous abortions; indications for abdominal delivery should be extended in such cases.

[Evaluation of the effects of methods of suppurative-inflammatory complications prevention after cesarean section on cellular and humoral components of the immune system]. / Otsenka vliianiia na kletochnyi i gumoral'nyi komponenty immunnoi sistemy zhenshchiny nekotorykh metodov profilaktiki gnoino-vospalitel'nykh oslozhnenii posle kesareva secheniia.

The immune status of 73 pregnant women and puerperae, administered proteolysis inhibitors or common antibacterial therapy to prevent pyoseptic complications, was assessed before cesarean section and 1 and 7 days after it. The results indicate certain shifts in the immunity status of puerperae of all groups, which were the most expressed 1 day after surgery (reduced content of CD3 lymphocytes, IgG and IgA, and a marked increase of the content of C-reactive protein) and normalized by day 7 postoperation. These changes are most likely to be caused by the surgical intervention but not the infectious inflammatory process, which is proved by the absence of pyoseptic complications after prophylactic measures taken. Hence, proteolysis inhibitors, along with the traditional methods, may be recommended for the prevention of pyoseptic complications after cesarean section.

[The computer assessment of cardiotocograms during labor induction]. / Komp'iuternaia otsenka kardiotokogramm pri induktsii rodov.

IBC-3 computer-based automated system was used to analyze the cardiotocograms obtained in the course of 40 induced labors. Labor was induced by amniotomy in Group 1 parturients, by a combined method (amniotomy followed by i.v. droplet infusions of oxytocin and enzaprost) in Group 2 patients. No significant differences between the two groups were observed. Uterine contractility parameters were higher in Group 2. Clinical and computer-aided cardiotocographic investigations revealed no unfavorable effects of the before methods of labor induction on the mother, fetus, and newborn.

[Experience in the use of fetal monitor MKP-01 Nadezhda]. / Opyt primeneniia fetal'nogo monitora MKP-01 "Nadezhda".

Cardiotocograms were studied in 40 women during timely labor with the use of Nedezhda MKP-01 fetal monitor with real-time automated processing of the following parameters: fetal basal heart beat rate, amplitude and length of decelerated heart beat rate, amplitude and frequency of oscillations of heart beat rate, time of delayed deceleration minimum with respect to the peak of a uterine contraction. Developing acute fetal hypoxia was detected in 3 cases, that permitted timely abdominal deliveries to preserve the fetuses. The described device was found highly informative and valuable.

[Predicting the outcome of labor in women with contracted pelvis]. / Prognozirovanie iskhoda rodov dlia ploda u zhenshchin s anatomicheski uzkim tazom.

The authors suggest that the coefficient, representing the ratio between the sizes of the small pelvis section and fetal head section, be used for the prediction of labor outcome for the fetus in women with a contracted pelvis. When the coefficient values K1-K4 were lower than 1.32, 1.35, 0.68, and 0.79, more than 90% of the newborns developed signs of cerebral circulation disorders, this prompting the use of cesarean section for this group of pregnant women. Timely correction of the policy of labor management with due consideration for the anatomical features of the pelvis helped reduce the perinatal mortality in multigravidae to 5/1000, mainly at the expense of carrying out planned cesarean section and monitoring in labor.

[Diagnosis of disorders of the fetal status using computer-assisted cardiotocography]. / Diagnostika narushenii sostoianiia ploda v rodakh s pomoshch'iu komp'iuternoi kardiotokografii.

The diagnostic system of cardiotocogram analysis in real time scale is described, and the diagnostic data of computer cardiotocography in various periods of os dilatation presented. Analysis of correlations and regressions of the parameters reflecting disorders of the fetal status has shown that the most significant parameter in the diagnosis of fetal status abnormalities is variability from beat to beat.