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1.
Eksp Klin Farmakol ; 55(1): 35-8, 1992.
Artigo em Russo | MEDLINE | ID: mdl-1339042

RESUMO

Low-molecular heparin preparations (a Soviet sample and that manufactured by the Celsus Company) in vitro, added to bovine plasma possess a lower antifactor-II activity, less time of recalcification and partial thromboplastin time as compared to high-molecular heparin of equal concentration (mg/ml) or dose (Units/ml). After intravenous injection of low-molecular heparin preparations to animals in a dose of 50 Units/200 g bw the time of hemorrhage was far less, while anticoagulant activity was lower than in animals given the same dose of high-molecular heparin. Both injection of low-molecular and high-molecular heparin results in a rise of the intensity of non-enzymatic fibrinolysis in the animals' blood plasma.


Assuntos
Hemostasia/efeitos dos fármacos , Heparina de Baixo Peso Molecular/farmacologia , Heparina/farmacologia , Animais , Testes de Coagulação Sanguínea , Fibrinólise/efeitos dos fármacos , Heparina/administração & dosagem , Heparina de Baixo Peso Molecular/administração & dosagem , Injeções Intravenosas , Masculino , Peso Molecular , Ratos , Fatores de Tempo
2.
Sov Med ; (5): 41-3, 1991.
Artigo em Russo | MEDLINE | ID: mdl-1876920

RESUMO

Various techniques and blood separators were employed to obtain therapeutic doses of immature erythrocytes (neocytes) from blood of 18 donors. Regimens of neocyte apheresis, preparative efficiency of blood separators, morphofunctional and biophysical characteristics of neocytes obtained were compared. Neocyte apheresis shows promise for hematological patients dependent on red cells transfusion.


Assuntos
Remoção de Componentes Sanguíneos , Doadores de Sangue , Separação Celular/métodos , Transfusão de Eritrócitos , Humanos
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