[Characteristics of the metabolism and gonadal action in mice of tritium-labelled deoxycytidine]. / Osobennosti metabolizma i deistviia na gonady myshi mechennogo tritie dezoksitsitidina.

The levels of 3H-deoxycytidine binding in mice and rats were shown to depend on the amount of the carrier and the routes of administration, and the dynamics of its retention, on the dose and schedule of its administration. As estimated by the criterion of the testis mass decrease the 3H-deoxycytidine dose of 37 kBq/g is equivalent to gamma-radiation dose of 0.06 Gy. The coefficient of 3H-deoxycytidine absorption from the digestive tract of mice and rats is 2-10 times as high as that of 3H-thymidine, while both compounds administered to rats transcutaneously have the same absorption coefficients amounting to 0.02.

[Comparative study of the genetic effect of various tritium compounds in male mice]. / Sravnitel'noe izuchenie geneticheskogo éffekta razlichnykh soedinenii tritiia u samtsov myshi.

Comparative study of the genetic effect of some tritiated biogenic++ compounds and tritiated water was carried out. Reciprocal translocations induced in mice stem spermatogonia by 3H-glucose, 3H-glycine and 3H-lysine occur with similar frequency, whereas the difference in values of the absorbed doses of beta-irradiation in some cases was about two-fold. The highest genetic effect per unit of activity of 3H-nucleosides (3H-TdR and 3H-CdR) was revealed at lowest activities. The frequency of reciprocal translocations induced by 3H-TdR was twice as that induced by 3H-CdR.