Ankle-brachial index and diabetic neuropathy: study of 225 patients.

OBJECTIVE: To evaluate neuropathic pain and peripheral vascular disease in diabetics and compare this with the length of time since diagnosis in type 1, and type 2 diabetes. METHODS: A cross-sectional study with 225 diabetics chosen from their responses on the DN4 questionnaire, who were then evaluated with the ankle-brachial index (ABI), separating type 1 diabetes from type 2 diabetes. RESULTS: A higher incidence of neuropathic pain in those over 60 years of age showed an ABI > 1.3. Neuropathic pain was related to an abnormal ABI in 144 patients (64.2%). A statistically significant value was obtained in type 2 diabetes patients with more than 10 years from disease onset, 69 with altered ABI and 25 with normal ABI. There was an altered ABI (< 0.9) observed in 33% of type 1 diabetes patients and in 67% of type 2 diabetes patients. CONCLUSION: The ABI test in type 1 diabetes and type 2 diabetes patients is important even in those who are asymptomatic. A diagnosis of more than 10 years prior, regardless of the presence of neuropathic pain or ischemic signs, altered the ABI.

Ankle-brachial index and diabetic neuropathy: study of 225 patients / Index tornozelo-braquial e neuropatia diabética: estudo de 225 pacientes

ABSTRACT Objective To evaluate neuropathic pain and peripheral vascular disease in diabetics and compare this with the length of time since diagnosis in type 1, and type 2 diabetes. Methods A cross-sectional study with 225 diabetics chosen from their responses on the DN4 questionnaire, who were then evaluated with the ankle-brachial index (ABI), separating type 1 diabetes from type 2 diabetes. Results A higher incidence of neuropathic pain in those over 60 years of age showed an ABI > 1.3. Neuropathic pain was related to an abnormal ABI in 144 patients (64.2%). A statistically significant value was obtained in type 2 diabetes patients with more than 10 years from disease onset, 69 with altered ABI and 25 with normal ABI. There was an altered ABI (< 0.9) observed in 33% of type 1 diabetes patients and in 67% of type 2 diabetes patients. Conclusion The ABI test in type 1 diabetes and type 2 diabetes patients is important even in those who are asymptomatic. A diagnosis of more than 10 years prior, regardless of the presence of neuropathic pain or ischemic signs, altered the ABI.

RESUMO Objetivo Avaliar dor neuropática e doença vascular periférica em diabéticos e comparar com, tempo de diagnóstico de diabetes tipo 1(DM 1) e diabetes tipo 2(DM2). Métodos Estudo de corte transversal onde, 225 diabéticos responderam ao questionário (DN4) sendo submetidos ao índice tornozelo-braquial (ITB). Resultados predomínio de dor neuropática foi em pacientes acima de 60 anos com (DM2), com um ITB > 1,3 nesta população; assim a dor neuropática foi relacionada com o ITB anormal em 144 pacientes, total de 64,2%. Um valor estatisticamente significativo foi com (DM2).Um ITB alterado (< 0,9) em 33% no (DM 1) e em 67% (DM 2). Totalizando 132 indivíduos com alterações no ITB. Conclusão O teste ITB é útil em pacientes com DM 1 e DM 2 quando a dor neuropática é suspeita, mesmo em assintomáticos. E o tempo prolongado de diabetes (> 10 anos), independentemente da presença de dor ou sinais isquêmicos, alterou o ITB.

Manifestações neuropsiquiátricas da Síndrome de Fahr: relato de caso / Neuropsychiatric manifestations of Fahr's Syndrome: a case-report

As calcificações cerebrais são alterações relativamente comuns, podendo estar presentes em diversas condições clínicas. A Síndrome de Fahr é uma destas condições. Relatamos o caso de uma paciente com alterações do comportamento, do humor, desordens dos movimentos e crises convulsivas. Foram encontradas alterações tomográficas compatíveis com a Síndrome de Fahr e achados laboratoriais típicos do hipoparatireoidismo.

Brain calcifications are relatively common and may be present in various clinical conditions. Fahr's syndrome is one of those conditions. We report a patient with abnormal behavior, changes of mood, movement disorders and seizures. CT changes consistent with the pattern described for Fahr's Syndrome and laboratory findings typical of hypoparathyroidism were found.

Ankle-brachial index, a screening for peripheral obstructive arterial disease, and migraine - a controlled study.

BACKGROUND: Epidemiological studies support the association between migraine, especially migraine with aura, and vascular disorders. The ankle-brachial index (ABI) is largely used as a surrogate of peripheral obstructive arterial disorders (POAD). Accordingly, in this study we contrasted the ABI in individuals with migraine and in controls. METHODS: We investigated 50 migraineurs and 38 controls and obtained the ABI (ratio between the systolic arterial pressure obtained in the legs and in the arms) using digital sphygmomanometry. As per validation studies, we used the cut-off of 0.9 as the normal limit for the ABI. We adjusted for gender, use of contraceptive hormones, tabagism, and other cardiovascular risk factors. RESULTS: We found abnormal values of ABI, suggestive of mild or moderate POAD, in 31 individuals (35.2%). Mean value was 0.96 (standard deviation = 0.10). None of our patients had ABI < 0.4, which would suggest severe POAD. Mean ABI for migraineurs was 0.94 (0.11), and for controls it was 0.99 (0.09). Difference was significant (t = 2.21 and P = .022). After adjustments, ABI remained significantly associated with migraine status (P = .024). Adjustments were reasonably effective (chi(2) of Hosmer-Lemeshow = 1.06, P = .590). CONCLUSION: Our findings suggest that decreased values of ABI are more common in migraineurs than in controls. Although causality was not assessed by us, the relationship is of importance per se. Doctors should measure the ABI in individuals with migraine as an easy way to screen for cardiovascular risk.

Prospecçäo do binômio família - diabético juvenil: aspectos psicológicos / Prospection of the binomial family - diabetic juvenile patient: psychological aspects

A equipe multidisciplinar de tratamento de diabetes juvenil do Hospital do Servidor Público Municipal de Säo Paulo (HSPM), no decorrer da atuaçäo sobre o grupo, detectou modificaçöes no comportamento da família e do diabético juvenil. Com a finalidade de conhecer a profundidade e avaliar o tipo de alteraçöes que estavam se processando nesse binômio, foram efetuados inquéritos pertinentes, em 1983 e 1984. Esta massa de informaçöes foi comparada com as anotaçöes, conceito, queixas, impressöes e dados extraídos durante a convivência da equipe com os pacientes e pais. Os resultados mostraram que para o paciente, a doença constitue problema social, escolar e familiar que na maioria dos casos é negado. Este comportamento de negaçäo dos pacientes também foi detectado nos pais porém em menor grau. Uma apreciável parcela dos pacientes (37,4%) omite ser diabética, enquanto que os pais näo o fazem na esperança de que isso contribua favoravelmente no controle da doença. Embora negado, verificou-se que a doença do filho provocou em 36,9% um distanciamento do casal. Esses dados enfatizam a necessidade do tratamento do binômio paciente-família