RESUMO
In this cross-sectional study total glycosylated haemoglobin (Hb AIa+b+c) has been measured in 20 healthy non-pregnant women and in five groups of 20 healthy women at various times during pregnancy. A statistically significant decrease occurs in these minor haemoglobin fractions by about 20 weeks gestation and this reduced level is maintained throughout the rest of pregnancy. If diabetic patients are to have their control assessed during pregnancy by determination of these fractions this fact might be relevant.
Assuntos
Hemoglobina A/análise , Gravidez , Adulto , Glicemia , Estudos Transversais , Feminino , Humanos , Ferro/uso terapêuticoAssuntos
Química Clínica/história , Glicosúria/história , Cobre , História do Século XX , Humanos , Métodos , PicratosAssuntos
Glicosúria/diagnóstico , Ácido Ascórbico/urina , Reações Falso-Negativas , Feminino , Humanos , Métodos , GravidezAssuntos
Aminopirina , Glicemia/análise , Glucose Oxidase , Peroxidases , Cor , Oxirredução , Fatores de TempoAssuntos
Edema/sangue , Complicações na Gravidez/sangue , Eletroforese das Proteínas Sanguíneas , Proteínas Sanguíneas/análise , Cloretos/sangue , Anticoncepcionais Orais , Eritrócitos , Feminino , Hematócrito , Hemoglobinometria , Humanos , Concentração Osmolar , Fragilidade Osmótica , Potássio/sangue , Gravidez , Albumina Sérica/análise , Sódio/sangue , Fatores de Tempo , Ureia/sangueRESUMO
The relation of capillary to venous blood glucose concentration, whole blood to plasma values, and, where possible, the effect of pregnancy on the variables have been studied. We have not been able to show constant relations between capillary and venous blood glucose concentrations as have been implied by a W.H.O. expert committee on diabetes mellitus and the British Diabetic Association.The choice of anticoagulant was shown to have a negligible effect on the results of a single antibody-charcoal separation insulin assay method.
