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World J Urol ; 34(1): 3-11, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26497825

RESUMO

PURPOSE: Despite the fact that bladder cancer patients have the highest median age of any type of cancer, older patients with muscle invasion are often under-treated. METHODS: In this review, we report the most up to date literature on the patterns of care and treatment of older patients with muscle invasive bladder cancer. Data on under-treatment, geriatric principles, cystectomy, perioperative chemotherapy, and bladder preservation for older patients are presented and analyzed. CONCLUSION: Chronologic age should not exclude patients from curative-intent therapy. Functional age as determined by geriatric assessments and multidisciplinary evaluation can help clinicians decide on the best course of treatment for individual patients. Cystectomy, perioperative chemotherapy, and curative-intent bladder preservation are reasonable options in healthy older adults. Observation should be limited to patients with extremely poor performance status and very limited life expectancy.


Assuntos
Antineoplásicos/uso terapêutico , Carcinoma de Células de Transição/terapia , Cistectomia/métodos , Avaliação Geriátrica/métodos , Músculo Liso/patologia , Neoplasias da Bexiga Urinária/terapia , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Carcinoma de Células de Transição/patologia , Humanos , Invasividade Neoplásica , Tratamentos com Preservação do Órgão , Medição de Risco , Neoplasias da Bexiga Urinária/patologia
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