1.
Analyst
; 140(16): 5459-63, 2015 Aug 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26140547
RESUMO
We report a novel sensing method for fluorescence-labelled microRNAs (miRNAs) spotted on an all-dielectric photonic structure. Such a photonic structure provides an enhanced excitation and a directional beaming of the emitted fluorescence, resulting in a significant improvement of the overall signal collected. As a result, the Limit of Detection (LoD) is demonstrated to decrease by a factor of about 50. A compact read-out system allows a wide-field imaging-based detection, with little or no optical alignment issues, which makes this approach particularly interesting for further development for example in microarray-type bioassays.
Assuntos
Técnicas Biossensoriais/métodos , MicroRNAs/análise , Fótons , Espectrometria de Fluorescência/métodos , Fluorescência , Humanos , Limite de Detecção , MicroRNAs/genética
2.
Med Educ
; 31(1): 72, 1997 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9231129