RESUMO
IgG4-related disease is a newly described systemic autoimmune and allergic disease, characterized histologically by a fibroinflammatory response with IgG4 plasma cells. It was initially described as affecting the pancreas, but commonly involves the head and neck region as well. While a biopsy is essential for definitive diagnosis, cross sectional imaging may be the initial modality which may suggest this entity. We describe a case of pathologically proven IgG4 related disease which highlights some key radiologic features seen in this entity. Our case highlights some key radiological features of IgG4- related disease in the head and neck, with involvement of the lacrimal glands, pituitary gland and cranial nerves on CT.
Assuntos
Doença Relacionada a Imunoglobulina G4/diagnóstico , Doenças Orbitárias/diagnóstico , Humanos , Doença Relacionada a Imunoglobulina G4/complicações , Doença Relacionada a Imunoglobulina G4/diagnóstico por imagem , Doença Relacionada a Imunoglobulina G4/patologia , Aparelho Lacrimal/patologia , Masculino , Pessoa de Meia-Idade , Doenças Orbitárias/diagnóstico por imagem , Doenças Orbitárias/etiologia , Doenças Orbitárias/patologia , Tomografia Computadorizada por Raios XRESUMO
"Enlarged parietal foramina" is a congenital malformation with autosomal dominant inheritance. The condition is usually self-limiting and doesn't require any treatment. However, it may also be associated with encephalocele, vascular anomalies or may be a part of syndrome. We present a case of enlarged parietal foramina in a child and discuss its imaging findings and the associated intracranial vascular malformations.
