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Vestn Oftalmol ; 125(1): 55-7, 2009.
Artigo em Russo | MEDLINE | ID: mdl-19284105

RESUMO

There are current tendencies in the use of photodynamic therapy (PDT) in combination with intravitreal injection of long-acting corticosteroids. Kenalog was intavitreally injected in patients with abnormal myopia (4 eyes), multifocal choroiditis (3 eyes), and age-related macular degeneration (6 eyes), and idiopathic choroidal neovascularization (CNV) (1 eye) 10-14 days before PDT. All the above cases were characterized by a severe clinical course with significantly diminished visual function, and evident exudative-hemorrhagic manifestations. A 2-5-line vision increase and bleeding resorption were observed in the patients 1-2 months after PDT. The results of optical coherent tomography suggest a significant reduction or disappearance of exudative manifestations (retinal edema, detachments of the neuroepithelium or pigment epithelium). Fluorescence angiography revealed decreased or ceased dye diffusion in the CNV areas at the late stages of the study. The findings suggest the efficiency of combined therapy for CNV that can improve visual prognosis significantly in patients after PDT.


Assuntos
Neovascularização de Coroide/tratamento farmacológico , Glucocorticoides/administração & dosagem , Fotoquimioterapia/métodos , Fármacos Fotossensibilizantes/uso terapêutico , Porfirinas/uso terapêutico , Triancinolona Acetonida/administração & dosagem , Neovascularização de Coroide/diagnóstico , Quimioterapia Combinada , Angiofluoresceinografia , Seguimentos , Fundo de Olho , Glucocorticoides/uso terapêutico , Humanos , Injeções , Microscopia Acústica , Fatores de Tempo , Tomografia de Coerência Óptica , Resultado do Tratamento , Triancinolona Acetonida/uso terapêutico , Verteporfina , Corpo Vítreo
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