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J AAPOS ; 27(6): 377-378, 2023 12.
Artigo em Inglês | MEDLINE | ID: mdl-37871794

RESUMO

We report the case of a 15-year-old boy with severe inflammatory blepharitis who was being treated with a TNFα inhibitor for Crohn's disease (CD). This case shows the potential utility of a skin biopsy in distinguishing metastatic CD associated with granulomatous blepharitis from a paradoxical blepharitis induced by anti-TNFα. It also demonstrates that ustekinumab can be considered in patients with CD who cannot tolerate TNFα inhibitors because of cutaneous paradoxical reactions.


Assuntos
Doença de Crohn , Masculino , Humanos , Adolescente , Doença de Crohn/complicações , Doença de Crohn/tratamento farmacológico , Fator de Necrose Tumoral alfa , Ustekinumab , Pele/patologia , Biópsia
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