Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 6 de 6
Filtrar
1.
Dig Endosc ; 23(2): 190-4, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21429028

RESUMO

We carried out a retrospective questionnaire survey of 792 submucosal colorectal carcinoma (CRC) cases from 15 institutions affiliated with the Colorectal Endoscopic Resection Standardization Implementation Working Group in Japanese Society for Cancer of the Colon and Rectum. In these cases, endoscopic resection (ER) and surveillance was carried out without additional surgical resection. Local recurrence or metastasis was observed in 18 cases. Local submucosal recurrence was observed in 11 cases, and metastatic recurrence was observed in 13 cases. Among the 15 cases in which the depth of submucosal invasion was measured, two cases showed depth less than 1000 µm, which has other risk factors for metastasis. Metastatic recurrence was observed in the lung, liver, lymph node, bone, adrenal glands, and the brain; in some cases, metastatic recurrence was observed in multiple organs. Death due to primary disease was observed in six cases. The average interval between ER and recurrence was 19.7 ± 9.2 months. In 16 cases, recurrence was observed within 3 years after ER. Thus, validity of ER without additional surgical resection for cases with the conditions that the depth of submucosal invasion is less than 1000 µm and the histological grade is well or moderately differentiated adenocarcinoma with no lymphatic and venous involvement was proven.


Assuntos
Adenocarcinoma/cirurgia , Colonoscopia , Neoplasias Colorretais/cirurgia , Mucosa Intestinal/cirurgia , Inquéritos e Questionários , Adenocarcinoma/mortalidade , Adenocarcinoma/patologia , Idoso , Idoso de 80 Anos ou mais , Neoplasias Colorretais/mortalidade , Neoplasias Colorretais/patologia , Progressão da Doença , Feminino , Humanos , Mucosa Intestinal/patologia , Japão , Masculino , Pessoa de Meia-Idade , Invasividade Neoplásica , Recidiva Local de Neoplasia/diagnóstico , Recidiva Local de Neoplasia/mortalidade , Vigilância da População , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/mortalidade , Guias de Prática Clínica como Assunto , Prognóstico , Fatores de Risco , Sociedades Médicas , Análise de Sobrevida
2.
Dig Endosc ; 22(4): 376-80, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-21175503

RESUMO

Bleeding, perforation, and residual/local recurrence are the main complications associated with colonoscopic treatment of colorectal tumor. However, current status regarding the average incidence of these complications in Japan is not available. We conducted a questionnaire survey, prepared by the Colorectal Endoscopic Resection Standardization Implementation Working Group, Japanese Society for Cancer of the Colon and Rectum (JSCCR), to clarify the incidence of postoperative bleeding, perforation, and residual/local recurrence associated with colonoscopic treatment. The total incidence of postoperative bleeding was 1.2% and the incidence was 0.26% with hot biopsy, 1.3% with polypectomy, 1.4% with endoscopic mucosal resection (EMR), and 1.7% with endoscopic submucosal dissection (ESD). The total incidence of perforation was 0.74% (0.01% with the hot biopsy, 0.17% with polypectomy, 0.91% with EMR, and 3.3% with ESD). The total incidence of residual/local recurrence was 0.73% (0.007% with hot biopsy, 0.34% with polypectomy, 1.4% with EMR, and 2.3% with ESD). Colonoscopic examination was used as a surveillance method for detecting residual/local recurrence in all hospitals. The surveillance period differed among the hospitals; however, most of the hospitals reported a surveillance period of 3-6 months with mainly transabdominal ultrasonography and computed tomography in combination with the colonoscopic examination.


Assuntos
Colonoscopia , Neoplasias Colorretais/diagnóstico , Neoplasias Colorretais/cirurgia , Hemorragia Gastrointestinal/epidemiologia , Perfuração Intestinal/epidemiologia , Neoplasia Residual/epidemiologia , Complicações Pós-Operatórias/epidemiologia , Biópsia , Neoplasias Colorretais/epidemiologia , Endossonografia , Humanos , Incidência , Japão/epidemiologia , Recidiva , Inquéritos e Questionários , Tomografia Computadorizada por Raios X
3.
J Gastroenterol Hepatol ; 25 Suppl 1: S99-S110, 2010 May.
Artigo em Inglês | MEDLINE | ID: mdl-20586876

RESUMO

BACKGROUND AND AIMS: The aim of the study was to examine whether the change in the prevalence of Helicobacter pylori infection had influenced upper gastrointestinal diseases in a recent 17-year period. METHODS: The prevalence of H. pylori infection was examined by serum H. pylori antibody tests in the subjects undergoing annual health checks at the Social Insurance Shiga Hospital in 1998 and 2005 (142 and 242 subjects, respectively). The prevalence of H. pylori infection in 1988 was estimated by parallel translation from the prevalence in 1998. A total of 2833 records of endoscopy performed in 1988 and 2005 at Otsu Municipal Hospital were studied. The age-adjusted prevalence of peptic ulcer, gastric cancer and reflux esophagitis were compared between 1988 and 2005. RESULTS: The age-adjusted prevalence of H. pylori infection significantly decreased in 2005 compared with 1988 (70.5-52.7%). The endoscopic records of 937 and 1246 patients in 1988 and 2005, respectively, were included in the analysis. The age-adjusted prevalence of peptic ulcer significantly decreased 0.34-fold in both men and women in 2005 compared with 1988. The age-adjusted prevalence of gastric cancer significantly decreased 0.44-fold in men, but did not change in women (0.99-fold), and overall significantly decreased 0.56-fold. The age-adjusted prevalence of reflux esophagitis significantly increased 6.6-, 2.7- and 4.8-fold in men, women and total, respectively. The increase was dominant in men aged 30-69 years. CONCLUSION: Over the 17-year period, accompanying the decreasing prevalence of H. pylori infection, the age-adjusted prevalence of peptic ulcer and gastric cancer decreased, but that of reflux esophagitis increased.


Assuntos
Gastroenteropatias/epidemiologia , Infecções por Helicobacter/epidemiologia , Infecções por Helicobacter/microbiologia , Helicobacter pylori/imunologia , Adulto , Distribuição por Idade , Fatores Etários , Idoso , Anticorpos Antibacterianos/sangue , Biomarcadores/sangue , Distribuição de Qui-Quadrado , Endoscopia Gastrointestinal , Esofagite Péptica/epidemiologia , Feminino , Gastroenteropatias/diagnóstico , Infecções por Helicobacter/diagnóstico , Humanos , Japão/epidemiologia , Masculino , Pessoa de Meia-Idade , Úlcera Péptica/epidemiologia , Prevalência , Estudos Retrospectivos , Distribuição por Sexo , Fatores Sexuais , Neoplasias Gástricas/epidemiologia , Fatores de Tempo , Adulto Jovem
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...