Anthropometric cutoff points to identify lipodystrophy characteristics in people living with HIV/AIDS: an observational study / Puntos de corte antropométricos para identificar las características de la lipodistrofia en personas que viven con VIH/SIDA: un estudio observacional

Introduction: currently, there is no consensus regarding accurate and low-cost methods for diagnosing lipodystrophy in people living with HIV/ AIDS (PLWHA). The aim of this study was to propose anthropometric cutoff points for the diagnosis of lipodystrophy among PLWHA. Methods: we included 106 PLWHA (men = 65, women = 41) who are under antiretroviral therapy and have been clinically classified into either a "lipodystrophy" or "non-lipodystrophy" group. Anthropometric measurements included 19 regions of body perimeters and 6 skinfold thickness measures. The Youden index was used to establish anthropometric cutoff points for the diagnosis of lipodystrophy, using the mean values of the anthropometric data (referred to as "original") along with the "Z index" (ZI) values, which were adjusted by the "Phantom Strategy." The cutoff points were proposed when "original" anthropometric measurements and ZI values had a statistical significance of p < 0.01 and an area under the curve (AUC) higher than 70%. The size effect was assessed to verify the influence of lipodystrophy on each anthropometric measure. Results: our data analysis proposes sex-specific cutoff points for the diagnosis of lipodystrophy in PLWHA - 17 points using the "original" anthropometric measurements, and 20 using the ZI values (average effect size between 1.0 and 1.1, and AUC = 76.7% and 78%). Conclusions: our study proposes accurate cutoff points for the diagnosis of lipodystrophy using "original" anthropometric measurements and ZI values adjusted by the "Phantom Strategy." Our findings support the use of anthropometric measurements as a simplified method for diagnosing lipodystrophy and monitoring body composition alterations in people living with HIV/AIDS

Introducción: no existe consenso con respecto a métodos precisos y de bajo coste para diagnosticar la lipodistrofia en personas que viven con VIH/SIDA (PVVS). El objetivo de este estudio es proponer puntos de corte antropométricos para el diagnóstico de lipodistrofia entre las PVVS. Métodos: se incluyeron 106 PVVS (hombres = 65, mujeres = 41) en tratamiento antirretroviral que se clasificaron clínicamente en dos grupos de "lipodistrofia" o "no lipodistrofia". Las mediciones antropométricas incluyeron 19 regiones de parámetros corporales y 6 medidas de pliegues cutáneos. El índice de Youden se utilizó para establecer puntos de corte antropométricos para el diagnóstico de lipodistrofia utilizando la media de los datos antropométricos (denominados "originales") junto con los valores del "índice Z" (IZ), que fueron ajustados por la "estrategia Phantom". Los puntos de corte se propusieron cuando las mediciones antropométricas "originales" y los valores de IZ fueron estadísticamente significativos con un valor p < 0,01 y un área bajo la curva (AUC) superior al 70%. Se evaluó el tamaño del efecto para verificar la influencia de la lipodistrofia en cada medida antropométrica. Resultados: se propusieron puntos de corte específicos según el sexo para el diagnóstico de lipodistrofia en PVVS: 17 puntos usando las medidas antropométricas "originales" y 20 usando los valores de IZ (tamaño del efecto promedio entre 1.0 y 1.1, y AUC = 76.7% y 78%). Conclusiones: se propusieron puntos de corte antropométricos para el diagnóstico de lipodistrofia. Las mediciones antropométricas son un método simplificado para diagnosticar y monitorear los cambios de composición corporal en las PVVS

Anthropometric cutoff points to identify lipodystrophy characteristics in people living with HIV/AIDS: an observational study.

INTRODUCTION: Introduction: currently, there is no consensus regarding accurate and low-cost methods for diagnosing lipodystrophy in people living with HIV/AIDS (PLWHA). The aim of this study was to propose anthropometric cutoff points for the diagnosis of lipodystrophy among PLWHA. Methods: we included 106 PLWHA (men = 65, women = 41) who are under antiretroviral therapy and have been clinically classified into either a "lipodystrophy" or "non-lipodystrophy" group. Anthropometric measurements included 19 regions of body perimeters and 6 skinfold thickness measures. The Youden index was used to establish anthropometric cutoff points for the diagnosis of lipodystrophy, using the mean values of the anthropometric data (referred to as "original") along with the "Z index" (ZI) values, which were adjusted by the "Phantom Strategy." The cutoff points were proposed when "original" anthropometric measurements and ZI values had a statistical significance of p < 0.01 and an area under the curve (AUC) higher than 70%. The size effect was assessed to verify the influence of lipodystrophy on each anthropometric measure. Results: our data analysis proposes sex-specific cutoff points for the diagnosis of lipodystrophy in PLWHA - 17 points using the "original" anthropometric measurements, and 20 using the ZI values (average effect size between 1.0 and 1.1, and AUC = 76.7% and 78%). Conclusions: our study proposes accurate cutoff points for the diagnosis of lipodystrophy using "original" anthropometric measurements and ZI values adjusted by the "Phantom Strategy." Our findings support the use of anthropometric measurements as a simplified method for diagnosing lipodystrophy and monitoring body composition alterations in people living with HIV/AIDS.

INTRODUCCIÓN: Introducción: no existe consenso con respecto a métodos precisos y de bajo coste para diagnosticar la lipodistrofia en personas que viven con VIH/SIDA (PVVS). El objetivo de este estudio es proponer puntos de corte antropométricos para el diagnóstico de lipodistrofia entre las PVVS. Métodos: se incluyeron 106 PVVS (hombres = 65, mujeres = 41) en tratamiento antirretroviral que se clasificaron clínicamente en dos grupos de "lipodistrofia" o "no lipodistrofia". Las mediciones antropométricas incluyeron 19 regiones de parámetros corporales y 6 medidas de pliegues cutáneos. El índice de Youden se utilizó para establecer puntos de corte antropométricos para el diagnóstico de lipodistrofia utilizando la media de los datos antropométricos (denominados "originales") junto con los valores del "índice Z" (IZ), que fueron ajustados por la "estrategia Phantom". Los puntos de corte se propusieron cuando las mediciones antropométricas "originales" y los valores de IZ fueron estadísticamente significativos con un valor p < 0,01 y un área bajo la curva (AUC) superior al 70%. Se evaluó el tamaño del efecto para verificar la influencia de la lipodistrofia en cada medida antropométrica. Resultados: se propusieron puntos de corte específicos según el sexo para el diagnóstico de lipodistrofia en PVVS: 17 puntos usando las medidas antropométricas "originales" y 20 usando los valores de IZ (tamaño del efecto promedio entre 1.0 y 1.1, y AUC = 76.7% y 78%). Conclusiones: se propusieron puntos de corte antropométricos para el diagnóstico de lipodistrofia. Las mediciones antropométricas son un método simplificado para diagnosticar y monitorear los cambios de composición corporal en las PVVS.

Un análisis crítico sobre las recomendaciones de actividad física en España / A critical analysis of physical activity recommendations in Spain

Objetivo: Identificar los documentos oficiales de las comunidades autónomas en España que contengan recomendaciones sobre actividad física, para evaluar el grado de conformidad con las recomendaciones sobre actividad física para la salud de la Organización Mundial de la Salud (OMS).MétodosSe realizó un análisis de contenido sobre 55 documentos de las consejerías de sanidad de los distintos gobiernos autonómicos que contienen recomendaciones sobre actividad física.ResultadosEl 84% de las comunidades autónomas en España hacen algún tipo de recomendación sobre actividad física aeróbica y el 37% sobre fortalecimiento muscular. Sin embargo, las que tienen documentos en consonancia con los criterios de la OMS son: actividad física aeróbica (n=11, 58%), personas adultas (n=10, 53%), personas mayores (n=5, 26%), infancia/adolescentes (n=1, 5%); fortalecimiento muscular, personas adultas (n=6, 32%), personas mayores (n=3, 16%), infancia/adolescentes (n=1, 5%); equilibrio (n=5, 26%); al menos 10 minutos continuados de actividad física (n=6, 32%); recomiendan hasta 300 minutos semanales (n=10, 53%); intensidad de la actividad física (n=2, 11%).ConclusionesLas recomendaciones hacen referencia a la actividad física aeróbica y apenas tienen en cuenta el fortalecimiento muscular. Una comunidad autónoma se ajusta a las recomendaciones de la OMS. Las comunidades con mayores índices de envejecimiento y mayor porcentaje de infancia/adolescentes casi no hacen recomendaciones sobre actividad física de acuerdo con las directrices de la OMS (AU)

Objective: To identify official documents with recommendations on physical activity published by theautonomous regions of Spain with the goal of evaluating their compliance with the physical activityrecommendations of the World Health Organization (WHO).Methods: We conducted a content analysis of 55 documents of the ministries of health of several regionalgovernments containing recommendations on physical activity.Results: Eighty-four percent of the autonomous regions in Spain made recommendations on aerobicphysical activity and 37% made recommendations on strength training. However, the number of documents consistent with theWHO criteria was as follows: aerobic activity (n = 11, 58%), adults (n = 10, 53%),the elderly (n = 5, 26%), children/adolescents (n = 1, 5%); strength training, adults (n = 6, 32%), the elderly(n = 3, 16%), children/adolescents (n = 1, 5%); balance (n = 5, 26%); at least 10minutes continuous physicalactivity (n = 6, 32%); recommendation of up to 300minutes per week (n = 10, 53%); intensity of physicalactivity (n = 2, 11%).Conclusions: The recommendations of the autonomous regions tend to focus on aerobic physical activityand to under-represent strength training. Moreover, only one autonomous region conforms to the WHOrecommendations for physical activity. The regions with higher rates of population aging and a higherpercentage of children and adolescents fail to make recommendations on physical activity consistentwith the WHO guidelines (AU)

[A critical analysis of physical activity recommendations in Spain]. / Un análisis crítico sobre las recomendaciones de actividad física en España.

OBJECTIVE: To identify official documents with recommendations on physical activity published by the autonomous regions of Spain with the goal of evaluating their compliance with the physical activity recommendations of the World Health Organization (WHO). METHODS: We conducted a content analysis of 55 documents of the ministries of health of several regional governments containing recommendations on physical activity. RESULTS: Eighty-four percent of the autonomous regions in Spain made recommendations on aerobic physical activity and 37% made recommendations on strength training. However, the number of documents consistent with the WHO criteria was as follows: aerobic activity (n=11, 58%), adults (n=10, 53%), the elderly (n=5, 26%), children/adolescents (n=1, 5%); strength training, adults (n=6, 32%), the elderly (n=3, 16%), children/adolescents (n=1, 5%); balance (n=5, 26%); at least 10minutes continuous physical activity (n=6, 32%); recommendation of up to 300minutes per week (n=10, 53%); intensity of physical activity (n=2, 11%). CONCLUSIONS: The recommendations of the autonomous regions tend to focus on aerobic physical activity and to under-represent strength training. Moreover, only one autonomous region conforms to the WHO recommendations for physical activity. The regions with higher rates of population aging and a higher percentage of children and adolescents fail to make recommendations on physical activity consistent with the WHO guidelines.